FB2025_01 , released February 20, 2025
Allele: Dmel\CCT6G0057
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General Information
Symbol
Dmel\CCT6G0057
Species
D. melanogaster
Name
FlyBase ID
FBal0096841
Feature type
allele
Associated gene
Dmel\CCT6
Associated Insertion(s)
P{lacW}CCT6G0057
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
P-element activity
(Schäfer et al., 1999.3.29)
Progenitor genotype
Associated Insertion(s)
P{lacW}CCT6G0057
Cytology
Description
Allele components
Component
Use(s)
Inserted element
P{lacW}
Encoded product / tool
lacZ
Tagged with
Tag:NLS(P)
Mutations Mapped to the Genome
Curation Data
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
AJ426932
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Lethality occurs during the third larval instar.

      (Peter et al., 2002)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Half of the embryos from females triple heterozygous for CCT6G0057, Df(2L)Exel6034 and Df(3R)Exel6191 display a delay in furrow formation compared to controls.

      The proportion of embryos displaying a delay in furrow formation increases from 25% observed for embryos derived from Fmr13/Df(3R)Exel6265 females to 75% observed for embryos from females that are also heterozygous for Df(2L)Exel6034.

      (Monzo et al., 2010)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      Comments
      Comments

      P{lacW} not verified as causing the lethality.

      (Schäfer et al., 1999.3.29)
      External Crossreferences and Linkouts ( 1 )
      Crossreferences
      GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.
      Synonyms and Secondary IDs (7)
      Reported As
      Symbol Synonym
      CCT6G0057
      P(cct6)
      (Monzo et al., 2010)
      Tcp-1zeta[G0057]
      (Monzo et al., 2010)
      Tcp-1ζG0057
      l(1)G0022G0057
      l(1)G0057
      (Peter et al., 2002)
      l(1)G0057G0057
      (Schäfer et al., 1999.3.29, Schäfer et al., 1999.6.15)
      Name Synonyms
      Secondary FlyBase IDs
        References (5)