Allele Dmel\Dlc90F^EP3634

General Information
Symbol	Dmel\Dlc90F^EP3634	Species	D. melanogaster
Name		FlyBase ID	FBal0097091
Feature type	allele	Associated gene	Dmel\Dlc90F

Map ( GBrowse )	Untitled Document
Allele class
Mutagen	P-element activity
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2013_03
FB2013_02
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Nature of the Allele
Allele class
Mutagen	P-element activity (Caggese, 1999.5.14, Gene Disruption Project members, 2001-, Caggese et al., 2001)
Mutations Mapped to the Genome

Type Location Additional Notes References transposable element insertion site 3R:14,124,978..14,124,978 (Caggese, 1999.5.14, Zhu et al., 2005, Gene Disruption Project members, 2001-, Caggese et al., 2001)
Associated Sequence Data
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name

UniProtKB/Swiss-Prot
UniProtKB/TrEMBL

Progenitor genotype
Nature of the lesion	Statement Reference Insertion of P{EP} into the 5'UTR of Dlc90F, in reverse orientation. (Caggese et al., 2001) P{EP} is present at position 1671-1672, within the Dlc90F transcription unit. (Caggese, 1999.5.14)
Caused by insertion	P{EP}Dlc90F^EP3634 (Caggese, 1999.5.14, Zhu et al., 2005, Gene Disruption Project members, 2001-, Caggese et al., 2001)
Cytology
Phenotypic Data
Phenotypic Class
	male semi-sterile \| recessive, with Scer\GAL4[-]: (Caggese et al., 2001) viable, with Scer\GAL4[-]: (Caggese et al., 2001)
Phenotype Manifest In
	spermatozoon, with Scer\GAL4[-]: (Caggese et al., 2001)
Detailed Description
	Statement Reference Sperm of mutant males is non-motile. (Caggese et al., 2001)
External Data
Linkouts
Interactions
	Show the genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Enhancer of
Statement Reference Dlc90F^EP3634, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF is an enhancer of visible phenotype of Pvr^{Scer\UAS.T:λ\cI-DD}, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF (Zhu et al., 2005) Dlc90F^EP3634, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF is an enhancer of visible phenotype of Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF, btl::Egfr^{Scer\UAS.T:λ\cI-DD} (Zhu et al., 2005) Dlc90F^EP3634, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF is an enhancer of visible phenotype of Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF, btl^{Scer\UAS.T:λ\cI-DD}, stumps^{Scer\UAS.T:Zzzz\FLAG} (Zhu et al., 2005)
NOT Enhancer of
Statement Reference Dlc90F^EP3634, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF is a non-enhancer of visible phenotype of Cdc42^L89.Scer\UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF (Zhu et al., 2005) Dlc90F^EP3634, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF is a non-enhancer of visible phenotype of Rac1^N17.Scer\UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF (Zhu et al., 2005)
NOT Suppressor of
Statement Reference Dlc90F^EP3634, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF is a non-suppressor of visible phenotype of Cdc42^L89.Scer\UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF (Zhu et al., 2005) Dlc90F^EP3634, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF is a non-suppressor of visible phenotype of Rac1^N17.Scer\UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF (Zhu et al., 2005)
Phenotype Manifest In
Enhancer of
Statement Reference Dlc90F^EP3634, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF is an enhancer of eye phenotype of Pvr^{Scer\UAS.T:λ\cI-DD}, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF (Zhu et al., 2005) Dlc90F^EP3634, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF is an enhancer of eye phenotype of Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF, btl::Egfr^{Scer\UAS.T:λ\cI-DD} (Zhu et al., 2005) Dlc90F^EP3634, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF is an enhancer of eye phenotype of Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF, btl^{Scer\UAS.T:λ\cI-DD}, stumps^{Scer\UAS.T:Zzzz\FLAG} (Zhu et al., 2005)
NOT Enhancer of
Statement Reference Dlc90F^EP3634/Scer\GAL4[-] is a non-enhancer of embryonic/larval dorsal branch phenotype of stumps^ems7 (Zhu et al., 2005)
NOT Suppressor of
Statement Reference Dlc90F^EP3634/Scer\GAL4[-] is a non-suppressor of embryonic/larval dorsal branch phenotype of stumps^ems7 (Zhu et al., 2005)
Additional Comments
Genetic Interactions
Statement Reference
Xenogenetic Interactions
Statement Reference
Complementation & Rescue Data
Fails to complement	Dlc90F⁰⁵⁰⁸⁹ (Caggese et al., 2001) Dlc90F^05090b (Caggese et al., 2001)
Comments
Stocks ( 0 )

Notes on Origin
Discoverer

Comments
	Remobilization experiments show that excision of the P{EP} can be accompanied by reversion of the mutant sterility phenotype. (Caggese et al., 2001)
External Crossreferences & Linkouts
Other Crossreferences

Linkouts

Synonyms & Secondary IDs ( 2 )
Reported As
Symbol Synonym	Dlc90F^EP3634 Tctex^EP3634
Name Synonym
Secondary FlyBase IDs

References ( 4 )
Research paper	Zhu et al., 2005, Genetics 170(2): 767--777 A screen for genes that influence fibroblast growth factor signal transduction in Drosophila. [FBrf0187664] Caggese et al., 2001, Mol. Genet. Genomics 265(3): 436--444 dtctex-1, the Drosophila melanogaster homolog of a putative murine t-complex distorter encoding a dynein light chain, is required for production of functional sperm. [FBrf0137026]
Personal communication to FlyBase	Gene Disruption Project members, 2001-, (Computer file) (Computer file) [FBrf0132177] Caggese, 1999.5.14, Helping FlyBase: Tctex. Helping FlyBase: Tctex. [FBrf0108508]

Allele Dmel\Dlc90FEP3634

Allele Dmel\Dlc90F^EP3634