Allele Scer\GAL4^sca-P309

General Information
Symbol	Scer\GAL4^sca-P309	Species	S. cerevisiae
Name		FlyBase ID	FBal0097122
Feature type	allele	Associated gene	Scer\GAL4

Allele class
Mutagen
Recent Updates
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FB2013_03
FB2013_02
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Nature of the Allele
Allele class
Mutagen
Mutations Mapped to the Genome

Type Location Additional Notes References
Associated Sequence Data
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name

UniProtKB/Swiss-Prot
UniProtKB/TrEMBL

Progenitor genotype
Nature of the lesion	Statement Reference
Caused by insertion	P{GAL4}sca^P309 (Reddy and Rodrigues, 1999, Yu et al., 2005, Kanuka et al., 2005, Kanuka et al., 2005, Cai et al., 2003, Yu et al., 2000, Jhaveri et al., 2000, Reddy et al., 1999, Buescher et al., 2004, Sen et al., 2003, Kuranaga et al., 2006, Ishida et al., 2012, Koto et al., 2009, Ayyub et al., 2005)
Cytology
Phenotypic Data
Phenotypic Class
	cell polarity defective, with Gαi^Scer\UAS.cCa (Cai et al., 2003) cell polarity defective, with insc^Scer\UAS.cKa (Cai et al., 2003) increased cell number, with Cul-5^EP3390 (Ayyub et al., 2005) visible, with BacA\p35^Scer\UAS.cHa (Kanuka et al., 2005) visible, with Cul-5^EP3390 (Ayyub et al., 2005) visible, with Iap2^Scer\UAS.cIa (Kanuka et al., 2005) visible, with N^{int.SH.Scer\UAS} (Reddy and Rodrigues, 1999) visible, with Nc^{C318G.Scer\UAS} (Kanuka et al., 2005) visible, with Nc^{dsRNA.Scer\UAS} (Kanuka et al., 2005) visible, with pros^Scer\UAS.cMa (Reddy and Rodrigues, 1999) visible, with sgg^{D235G.D300G.Scer\UAS.T:Hsap\MYC} (Kanuka et al., 2005) visible, with sgg^{dsRNA.10.Scer\UAS} (Kanuka et al., 2005) visible, with sgg^{dsRNA.46.Scer\UAS} (Kanuka et al., 2005) visible, with th^Scer\UAS.cHa (Kanuka et al., 2005)
Phenotype Manifest In
	antenna, with N^DN.Scer\UAS (Sen et al., 2003) antenna, with numb^Scer\UAS.cWa (Sen et al., 2003) antenna, with pros^Scer\UAS.cMa (Sen et al., 2003) antennal segment 3 sensillum, with rst^Scer\UAS.cSa (Reddy et al., 1999) denticle \| ectopic, with mid^Scer\UAS.cBa (Buescher et al., 2004) embryonic/larval cuticle, with mid^Scer\UAS.cBa (Buescher et al., 2004) eo neuron \| supernumerary, with Nc^{C318G.Scer\UAS} (Kanuka et al., 2005) external sensory organ precursor cell IIa, with Cul-5^EP3390 (Ayyub et al., 2005) external sensory organ precursor cell IIb \| supernumerary, with Cul-5^EP3390 (Ayyub et al., 2005) fascicle & antennal segment 3, with N^DN.Scer\UAS (Sen et al., 2003) fascicle & antennal segment 3, with numb^Scer\UAS.cWa (Sen et al., 2003) glial cell & antennal segment 3 \| ectopic, with N^DN.Scer\UAS (Sen et al., 2003) glial cell & antennal segment 3 \| ectopic, with numb^Scer\UAS.cWa (Sen et al., 2003) macrochaeta, with Cul-5^EP3390 (Ayyub et al., 2005) macrochaeta, with ik2^{dsRNA.Scer\UAS} (Koto et al., 2009) macrochaeta, with sgg^{10.Scer\UAS.T:Hsap\MYC} (Kanuka et al., 2005) macrochaeta, with sgg^{ΔN300.Scer\UAS.T:Hsap\MYC} (Kanuka et al., 2005) macrochaeta \| supernumerary, with BacA\p35^Scer\UAS.cHa (Kanuka et al., 2005) macrochaeta \| supernumerary, with Iap2^Scer\UAS.cIa (Kanuka et al., 2005) macrochaeta \| supernumerary, with ik2^Scer\UAS.cKa (Kuranaga et al., 2006) macrochaeta \| supernumerary, with Nc^{C318G.Scer\UAS} (Kanuka et al., 2005) macrochaeta \| supernumerary, with Nc^{dsRNA.Scer\UAS} (Kanuka et al., 2005) macrochaeta \| supernumerary, with sgg^{D235G.D300G.Scer\UAS.T:Hsap\MYC} (Kanuka et al., 2005) macrochaeta \| supernumerary, with sgg^{dsRNA.10.Scer\UAS} (Kanuka et al., 2005) macrochaeta \| supernumerary, with sgg^{dsRNA.46.Scer\UAS} (Kanuka et al., 2005) macrochaeta \| supernumerary, with th^Scer\UAS.cHa (Kanuka et al., 2005) mechanosensory chaeta \| supernumerary, with ct^Scer\UAS.cLa (Jhaveri et al., 2000) microchaeta & antennal segment 3, with N^DN.Scer\UAS (Sen et al., 2003) microchaeta & antennal segment 3, with numb^Scer\UAS.cWa (Sen et al., 2003) microchaeta & antennal segment 3, with pros^Scer\UAS.cMa (Sen et al., 2003) neuroblast, with Gαi^Scer\UAS.cCa (Yu et al., 2003, Cai et al., 2003) neuroblast \| P-stage, with insc^Scer\UAS.cKa (Cai et al., 2003) sacculus, with rst^Scer\UAS.cSa (Reddy et al., 1999) scutum & external sensory organ & tormogen cell, with pros^Scer\UAS.cMa (Reddy and Rodrigues, 1999) scutum & external sensory organ & trichogen cell, with pros^Scer\UAS.cMa (Reddy and Rodrigues, 1999) sensillum basiconicum, with Egfr^DN.Scer\UAS (Jhaveri et al., 2000) sensillum coeloconicum \| ectopic, with Egfr^DN.Scer\UAS (Jhaveri et al., 2000) sensillum trichodeum, with Egfr^DN.Scer\UAS (Jhaveri et al., 2000) sensillum trichodeum of antennal segment 3, with rst^Scer\UAS.cSa (Reddy et al., 1999) sensory mother cell, with sgg^{10.Scer\UAS.T:Hsap\MYC} (Kanuka et al., 2005) sensory mother cell, with sgg^{ΔN300.Scer\UAS.T:Hsap\MYC} (Kanuka et al., 2005) sensory mother cell \| supernumerary, with ik2^Scer\UAS.cKa (Kuranaga et al., 2006) sensory mother cell \| supernumerary, with Nc^{C318G.Scer\UAS} (Kanuka et al., 2005) sensory mother cell \| supernumerary, with sgg^{D235G.D300G.Scer\UAS.T:Hsap\MYC} (Kanuka et al., 2005) sensory mother cell \| supernumerary, with th^{Scer\UAS.T:Zzzz\FLAG} (Kuranaga et al., 2006) sensory organ cell \| supernumerary, with Cul-5^EP3390 (Ayyub et al., 2005) spindle pole centrosome & astral microtubule, with Gαi^Scer\UAS.cCa (Yu et al., 2003) thecogen cell \| supernumerary, with Nc^{C318G.Scer\UAS} (Kanuka et al., 2005) tormogen cell, with N^{int.SH.Scer\UAS} (Reddy and Rodrigues, 1999) tormogen cell & antennal segment 3 \| conditional ts, with N^{int.SH.Scer\UAS} (Sen et al., 2003) tormogen cell & antennal segment 3 \| ectopic \| conditional ts, with N^{int.SH.Scer\UAS} (Sen et al., 2003) trichogen cell, with N^{int.SH.Scer\UAS} (Reddy and Rodrigues, 1999) trichogen cell & antennal segment 3 \| conditional ts, with N^{int.SH.Scer\UAS} (Sen et al., 2003) trichogen cell & antennal segment 3 \| ectopic \| conditional ts, with N^{int.SH.Scer\UAS} (Sen et al., 2003) ventral nerve cord primordium, with insc^Scer\UAS.cKa (Cai et al., 2003)
Detailed Description
	Statement Reference
External Data
Linkouts
Interactions
	Show the genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Suppressed by
Statement Reference Gαi^Scer\UAS.cCa, Scer\GAL4^sca-P309 has cell polarity defective phenotype, suppressible \| maternal effect \| partially by raps^P89 (Cai et al., 2003) Gαi^Scer\UAS.cCa, Scer\GAL4^sca-P309 has cell polarity defective phenotype, suppressible \| partially by raps[+]/raps^P89 (Cai et al., 2003)
Phenotype Manifest In
Enhanced by
Statement Reference Nc^{C318G.Scer\UAS}, Scer\GAL4^sca-P309 has macrochaeta \| supernumerary phenotype, enhanceable by sgg³² (Kanuka et al., 2005) Scer\GAL4^sca-P309, ik2^{dsRNA.Scer\UAS} has macrochaeta phenotype, enhanceable by Nc^{C318G.Scer\UAS.T:Avic\GFP-EGFP}, Scer\GAL4^sca-P309 (Koto et al., 2009, Koto et al., 2009) Scer\GAL4^sca-P309, ik2^{dsRNA.Scer\UAS} has macrochaeta phenotype, enhanceable by th^{Scer\UAS.T:Zzzz\FLAG}/Scer\GAL4^sca-P309 (Koto et al., 2009, Koto et al., 2009)
Suppressed by
Statement Reference Gαi^Scer\UAS.cCa, Scer\GAL4^sca-P309 has neuroblast phenotype, suppressible \| maternal effect \| partially by raps^P89 (Cai et al., 2003) Gαi^Scer\UAS.cCa, Scer\GAL4^sca-P309 has neuroblast phenotype, suppressible \| partially by raps[+]/raps^P89 (Cai et al., 2003) Gαi^Scer\UAS.cCa, Scer\GAL4^sca-P309 has spindle pole centrosome phenotype, suppressible by raps^unspecified (Yu et al., 2003) Nc^{C318G.Scer\UAS}, Scer\GAL4^sca-P309 has macrochaeta \| supernumerary phenotype, suppressible by wg^Sp-1 (Kanuka et al., 2005)
Enhancer of
Statement Reference Nc^{C318G.Scer\UAS.T:Avic\GFP-EGFP}, Scer\GAL4^sca-P309 is an enhancer of macrochaeta phenotype of Scer\GAL4^sca-P309, ik2^{dsRNA.Scer\UAS} (Koto et al., 2009, Koto et al., 2009) th^{Scer\UAS.T:Zzzz\FLAG}/Scer\GAL4^sca-P309 is an enhancer of macrochaeta phenotype of Scer\GAL4^sca-P309, ik2^{dsRNA.Scer\UAS} (Koto et al., 2009, Koto et al., 2009)
Additional Comments
Genetic Interactions
Statement Reference
Xenogenetic Interactions
Statement Reference
Complementation & Rescue Data
Rescues	raps^Scer\UAS.cYa/Scer\GAL4^sca-P309 rescues raps^P62 (Yu et al., 2000) raps^Scer\UAS.cYa/Scer\GAL4^sca-P309 rescues raps^P89 (Yu et al., 2000) Scer\GAL4^sca-P309/mid^Scer\UAS.cBa rescues mid^GA174 (Buescher et al., 2004)
Comments
Stocks ( 0 )

Notes on Origin
Discoverer

External Crossreferences & Linkouts
Other Crossreferences

Linkouts

Synonyms & Secondary IDs ( 2 )
Reported As
Symbol Synonym	GAL4^P309 (Reddy and Rodrigues, 1999) Scer\GAL4^sca-P309
Name Synonym
Secondary FlyBase IDs

References ( 15 )
Research paper	Ishida et al., 2012, PLoS ONE 7(2): e30265 Prevention of Apoptosis by Mitochondrial Phosphatase PGAM5 in the Mushroom Body Is Crucial for Heat Shock Resistance in Drosophila melanogaster. [FBrf0217492] Koto et al., 2009, J. Cell Biol. 187(2): 219--231 Temporal regulation of Drosophila IAP1 determines caspase functions in sensory organ development. [FBrf0209002] Kuranaga et al., 2006, Cell 126(3): 583--596 Drosophila IKK-related kinase regulates nonapoptotic function of caspases, via degradation of IAPs. [FBrf0194448] Ayyub et al., 2005, Dev. Dyn. 232(3): 865--875 Cullin-5 plays multiple roles in cell fate specification and synapse formation during Drosophila development. [FBrf0183913] Kanuka et al., 2005, EMBO J. 24(21): 3793--3806 Drosophila caspase transduces Shaggy/GSK-3beta kinase activity in neural precursor development. [FBrf0190361] Yu et al., 2005, Genes Dev. 19(11): 1341--1353 Locomotion defects, together with Pins, regulates heterotrimeric G-protein signaling during Drosophila neuroblast asymmetric divisions. [FBrf0187602] Buescher et al., 2004, Curr. Biol. 14(19): 1694--1702 Drosophila T box proteins break the symmetry of hedgehog-dependent activation of wingless. [FBrf0180065] Cai et al., 2003, Cell 112(1): 51--62 Apical complex genes control mitotic spindle geometry and relative size of daughter cells in Drosophila neuroblast and pI asymmetric divisions. [FBrf0155600] Sen et al., 2003, Dev. Biol. 254(1): 79--92 Combinatorial expression of Prospero, Seven-up, and Elav identifies progenitor cell types during sense-organ differentiation in the Drosophila antenna. [FBrf0158845] Yu et al., 2003, J. Cell Biol. 162(4): 623--633 Distinct roles of Galphai and Gbeta13F subunits of the heterotrimeric G protein complex in the mediation of Drosophila neuroblast asymmetric divisions. [FBrf0162191] Jhaveri et al., 2000, Mech. Dev. 99(1-2): 101--111 Sense organ identity in the Drosophila antenna is specified by the expression of the proneural gene atonal. [FBrf0131324] Yu et al., 2000, Cell 100(4): 399--409 Analysis of partner of inscuteable, a novel player of Drosophila asymmetric divisions, reveals two distinct steps in inscuteable apical localization. [FBrf0125333] Reddy and Rodrigues, 1999, Development 126(10): 2083--2092 Sibling cell fate in the Drosophila adult external sense organ lineage is specified by prospero function, which is regulated by Numb and Notch. [FBrf0108429] Reddy et al., 1999, Dev. Genes Evol. 209(10): 581--591 Irregular chiasm-C-roughest, a member of the immunoglobulin superfamily, affects sense organ spacing on the Drosophila antenna by influencing the positioning of founder cells on the disc ectoderm. [FBrf0112065]
Supplementary material	Kanuka et al., 2005, EMBO J. 24(21): Drosophila caspase transduces Shaggy/GSK-3beta kinase activity in neural precursor development. [FBrf0191762]

Allele Scer\GAL4sca-P309

Allele Scer\GAL4^sca-P309