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General Information
Symbol
Mmus\Cd8aUAS.cLa.EGFP
Species
M. musculus
Name
FlyBase ID
FBal0097215
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
UAS-mCD8-GFP, UAS-mCD8::GFP, UAS-CD8-GFP, UAS-mCD8GFP, UAS-CD8GFP, mCD8-GFP, UAS-CD8::GFP, mCD8::GFP, CD8-GFP, UAS-mCD8:GFP
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference
Coding region for Mmus\Cd8a is fused in frame, at its 3' end to EGFP, and expression of the fusion protein is governed by UASt regulatory sequences.
Allele components
Product class / Tool use(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference
Expression of Mmus\Cd8aScer\UAS.T:Avic\GFP in photoreceptors under the control of Scer\GAL4GMR.PF produces electroretinogram depolarisation amplitudes that are similar to controls.
Expression of Mmus\Cd8aScer\UAS.T:Avic\GFP under the control of Scer\GAL4CY2 in the follicle cells does not result in a mutant chorion phenotype.
Expression of Mmus\Cd8aScer\UAS.T:Avic\GFP under the control of Scer\GAL4C96 does not result in any wing defects. Expression of Mmus\Cd8aScer\UAS.T:Avic\GFP under the control of Scer\GAL4hs.2sev or Scer\GAL4GMR.PF does not have any effect on the eye. Animals expressing Mmus\Cd8aScer\UAS.T:Avic\GFP under the control of Scer\GAL4pnr-MD237 show wild type bristle formation.
Causes no toxicity throughout a cell's life.
External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Transgenic flies that express Scer\GAL4e33C>Mmus\Cd8aScer\UAS.T:Avic\GFP in asrij9 mutants show complete suppression of premature plasmatocyte differentiation.
The arrhythmicity caused by expression of G-sα60AQ215L.Scer\UAS in LN[[v]] neurons under the control of Scer\GAL4P0.5.Pdf in constant darkness is not suppressed by co-expression of Mmus\Cd8aScer\UAS.T:Avic\GFP.
Expression of Mmus\Cd8aScer\UAS.T:Avic\GFP with Hsap\CHMP2BIntron5.Scer\UAS does not affect the severity of the rough eye phenotype (both under the control of Scer\GAL4GMR.PF).
Co-expression of Mmus\Cd8aScer\UAS.T:Avic\GFP does not enhance the reduction in electroretinogram depolarisation amplitude seen when Zzzz\CAGQ48.Scer\UAS.T:Hsap\MYC,T:Zzzz\FLAG is expressed in photoreceptors under the control of Scer\GAL4GMR.PF.
The border follicle cell migration defect seen in egg chambers expressing PvrDN.Scer\UAS under the control of Scer\GAL4slbo.2.6 is not suppressed by coexpression of Mmus\Cd8aScer\UAS.T:Avic\GFP. The border follicle cell migration defect seen in egg chambers expressing Rac1N17.Scer\UAS under the control of Scer\GAL4slbo.2.6 is not suppressed by coexpression of Mmus\Cd8aScer\UAS.T:Avic\GFP.
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (101)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (5)
Reported As
Symbol Synonym
Mmus\Cd8aScer\UAS.T:Avic\GFP
Mmus\Cd8aUAS.cLa.EGFP
Mus\Cd8aScer\UAS.T:Avic\GFP
UAS-mCD8-GFP
Name Synonyms
Secondary FlyBase IDs
    References (927)