A Database of Drosophila Genes & Genomes

FB2008_07, released August 8, 2008
 

Allele Mmus\Cd8aScer\UAS.T:Avic\GFP

General Information
SymbolMmus\Cd8aScer\UAS.T:Avic\GFPSpeciesM. musculus
NameFlyBase IDFBal0097215
Feature typealleleCreated / Updated2006-08-20/2006-08-20
Associated geneMmus\Cd8a
Allele class
Mutagenin vitro construct | regulatory fusionin vitro construct | coding region fusion
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Allele class
Mutagen
Mapped Features and Mutations
Type
Symbol & Location
Additional Notes
References
 
 
 
 
Associated Sequence Data
DDBJ /
EMBL /
GenBank
DNA sequence
Protein sequence
Name
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Progenitor genotype
      Nature of the lesion
      Statement
      Reference
      Construct: Coding region for Mmus\Cd8a is fused in frame, at its 3' end to Avic\GFP (F64L, S65T), and expression of the fusion protein is governed by Scer\UAS regulatory sequences.
      Assay mode
      Carried in construct
      (Denholm et al., 2005, Renault et al., 2004, Wang et al., 2004, Pielage et al., 2006, Millard et al., 2007, Bianco et al., 2007, Fei et al., 2002, Ditch et al., 2005, Apitz et al., 2005, Benton et al., 2007, Murakami et al., 2007, Sanchez-Soriano and Prokop, 2005, Orihara-Ono et al., 2005, Ramaekers et al., 2005, Rawson et al., 2005, Chen et al., 2005, Tsuda et al., 2005, Fishilevich and Vosshall, 2005, Bello et al., 2003, Hummel et al., 2003, Murthy et al., 2003, Van Doren et al., 2003, Hsiung et al., 2005, Maurel-Zaffran et al., 2001, Grueber et al., 2002, Fishilevich et al., 2005, Mirth et al., 2005, Fan et al., 2005, Nern et al., 2005, Rodriguez Moncalvo and Campos, 2005, Sanchez-Soriano et al., 2005, Sykes and Condron, 2005, Lee et al., 1999, Brown et al., 2006, Kueppers et al., 2003, Monier et al., 2005, Zheng et al., 2006, Scott et al., 2003, Sokol and Ambros, 2005, Wang et al., 2002, Jefferis et al., 2001, Sugimura et al., 2003, Hewes et al., 2003, Wong et al., 2002, Marin et al., 2002, Cole et al., 2005, Cohen et al., 2002, Wang and Struhl, 2005, Pascual and Preat, 2001, Landgraf et al., 2003, Williams and Truman, 2005, Subramanian et al., 2003, Jefferis et al., 2002, Leyssen et al., 2005, Watts et al., 2003, Manoli et al., 2005, Kimura et al., 2005, Li and Gao, 2003, Malpel et al., 2002, Kuo et al., 2005, Fabrizio et al., 2003, Masuda-Nakagawa et al., 2005, Kurusu et al., 2002, Inoshita and Tanimura, 2006, Goldstein, 2005, Billuart et al., 2001, Dobritsa et al., 2003, Cenci and Gould, 2005, Kim et al., 2006, Friedman and Perrimon, 2006, Mandal et al., 2007, Krzemien et al., 2007, Ebacher et al., 2007, Nicolas and Preat, 2005, Zhu et al., 2006, Kobayashi et al., 2006, Behan et al., 2002, Reuter et al., 2003, Ang et al., 2003, Komiyama et al., 2003, Rulifson et al., 2002, Hrdlicka et al., 2002, Presente et al., 2002, Moore et al., 2002, Duffy, 2002, Sweeney et al., 2002, Martinez-Campos et al., 2004, Williams and Shepherd, 2002, Lohr et al., 2002, Geisbrecht and Montell, 2004, Rulifson et al., 2002, Ng et al., 2002, Baker et al., 2004, Comas et al., 2004, Alvarado et al., 2004, Morales et al., 2002, Lee and Park, 2004, Nicolai et al., 2003, Zhu and Luo, 2004, Hummel and Zipursky, 2004, Rolls et al., 2003, Kango-Singh et al., 2002, Neves et al., 2004, Dubruille et al., 2002, Ponzielli et al., 2002, Moore et al., 2004, Brumby and Richardson, 2003, Gendre et al., 2004, Dearborn and Kunes, 2004, Lee et al., 2003, Canamasas et al., 2003, Xu et al., 2002, Kuppers-Munther et al., 2004, Acebes et al., 2004, Rival et al., 2004, Awasaki and Ito, 2004, Watts et al., 2004, Boquet et al., 2000, Tanaka et al., 2004, Jefferis et al., 2004, Ye et al., 2004, Voas and Rebay, 2003, Chyb et al., 2003, De Joussineau et al., 2003, Wilson et al., 2004, Kiger et al., 2000, Scott et al., 2001, Lee et al., 2000, Williams et al., 2000, Martini et al., 2000, Tonning et al., 2005, Bai et al., 2000, Sung and Robinow, 2000, Lee et al., 2000, Luo et al., 1999, Lee and Luo, 1999, Lee et al., 2005, Rosenzweig et al., 2005, Marin et al., 2005, Ting et al., 2005, Sinenko et al., 2004, Kim and Rulifson, 2004, Rival et al., 2004, Pascual et al., 2005, Taillebourg et al., 2005, Xu et al., 2004, Liu et al., 2000, Kuzin et al., 2005, Kuzin et al., 2005, Carhan et al., 2004, Davidson et al., 2005, Thorne et al., 2004, Yang and Kunes, 2004, Ng and Luo, 2004, Larsson et al., 2004, Lee and Treisman, 2004, Tayler et al., 2004, Adam and Montell, 2004, Truman et al., 2004, Shandala et al., 2004, Apitz et al., 2004, Pan et al., 2004, Wojtowicz et al., 2004, Emoto et al., 2004, Hitier et al., 2001, Winter et al., 2001, Fujioka et al., 2003, Eldar et al., 2003, Somers and Saint, 2003, Han et al., 2003, Sarpal et al., 2003, Peng et al., 2003, Justice et al., 2003, Schubiger et al., 2003, Grueber et al., 2003, Jenkins et al., 2003, Rawson, 2005, Long et al., 2006, Pitman et al., 2006, Choe et al., 2006, Choi et al., 2006, Parker, 2006, Bello et al., 2006, Bernard et al., 2006, Shang et al., 2007, McDonald et al., 2006, Jones et al., 2006, Khodosh et al., 2006, Whited et al., 2007, Yu et al., 2005, Betschinger et al., 2006, Chen et al., 2006, Mathews et al., 2006, Wang et al., 2006, Jafar-Nejad et al., 2006, Kim et al., 2006, Lalevee et al., 2006, Keene et al., 2006, Soller et al., 2006, Chotard et al., 2005, Lee et al., 2006, Mahr and Aberle, 2006, Komiyama, 2007, Ashraf et al., 2006, Ang et al., 2006, Parrish et al., 2006, Gregory et al., 2007, Berdnik et al., 2006, Komiyama et al., 2004, Goldman et al., 2005, Kreher et al., 2005, Arya et al., 2006, Basto et al., 2006, Augustin et al., 2007, Wang and Struhl, 2004, Sweeney et al., 2006, Bazigoui et al., 2007, Boyle et al., 2006, Ward et al., 2006, Girard et al., 2006, Srahna et al., 2006, Li et al., 2006, Benton et al., 2006, Fayyazuddin et al., 2006, D'Alterio et al., 2005, Larsen et al., 2006, Kurtovic et al., 2007, Hyun et al., 2006, Thomas and van Meyel, 2007, Bello et al., 2007, Williams and Truman, 2004, Jefferis et al., 2007, Jones et al., 2007, Lin et al., 2007, Zhu et al., 2005, Mehren and Griffith, 2004, Sugimura et al., 2004, Li et al., 2004, Honjo and Furukubo-Tokunaga, 2005, Wilson and Laurent, 2005, Roegiers et al., 2005, Assa-Kunik et al., 2007, Benton et al., 2007, Liu et al., 2007, Grieder et al., 2007, Friggi-Grelin et al., 2006, Schnorrer et al., 2007)
      Tagged with
      (Lee and Luo, 1999, Lee et al., 1999, Luo et al., 1999, Lee et al., 2000, Sung and Robinow, 2000, Martini et al., 2000, Boquet et al., 2000, Kiger et al., 2000, Liu et al., 2000, Williams et al., 2000, Bai et al., 2000, Lee et al., 2000, Scott et al., 2001, Winter et al., 2001, Hitier et al., 2001, Billuart et al., 2001, Maurel-Zaffran et al., 2001, Pascual and Preat, 2001, Jefferis et al., 2001, Jefferis et al., 2002, Malpel et al., 2002, Kurusu et al., 2002, Wang et al., 2002, Wong et al., 2002, Marin et al., 2002, Cohen et al., 2002, Sweeney et al., 2002, Grueber et al., 2002, Morales et al., 2002, Rulifson et al., 2002, Ng et al., 2002, Williams and Shepherd, 2002, Rulifson et al., 2002, Behan et al., 2002, Xu et al., 2002, Ponzielli et al., 2002, Dubruille et al., 2002, Kango-Singh et al., 2002, Lohr et al., 2002, Moore et al., 2002, Duffy, 2002, Presente et al., 2002, Hrdlicka et al., 2002, Komiyama et al., 2003, Reuter et al., 2003, Ang et al., 2003, Bello et al., 2003, Hummel et al., 2003, Murthy et al., 2003, Grueber et al., 2003, Justice et al., 2003, Somers and Saint, 2003, Van Doren et al., 2003, Kueppers et al., 2003, Scott et al., 2003, Sugimura et al., 2003, Dobritsa et al., 2003, Fabrizio et al., 2003, Landgraf et al., 2003, Li and Gao, 2003, Subramanian et al., 2003, Watts et al., 2003, Jenkins et al., 2003, Schubiger et al., 2003, Peng et al., 2003, Han et al., 2003, Sarpal et al., 2003, Eldar et al., 2003, Fujioka et al., 2003, Lee et al., 2003, Jefferis et al., 2004, Gendre et al., 2004, Brumby and Richardson, 2003, Voas and Rebay, 2003, Rolls et al., 2003, Zelhof and Hardy, 2004, Nicolai et al., 2003, De Joussineau et al., 2003, Chyb et al., 2003, Wilson et al., 2004, Canamasas et al., 2003, Ye et al., 2004, Tanaka et al., 2004, Rival et al., 2004, Awasaki and Ito, 2004, Watts et al., 2004, Acebes et al., 2004, Kuppers-Munther et al., 2004, Dearborn and Kunes, 2004, Moore et al., 2004, Neves et al., 2004, Zhu and Luo, 2004, Hummel and Zipursky, 2004, Lee and Park, 2004, Alvarado et al., 2004, Comas et al., 2004, Baker et al., 2004, Geisbrecht and Montell, 2004, Martinez-Campos et al., 2004, Thorne et al., 2004, Xu et al., 2004, Rival et al., 2004, Kim and Rulifson, 2004, Sinenko et al., 2004, Wojtowicz et al., 2004, Emoto et al., 2004, Sykes et al., 2004, Pan et al., 2004, Apitz et al., 2004, Shandala et al., 2004, Truman et al., 2004, Tayler et al., 2004, Adam and Montell, 2004, Lee and Treisman, 2004, Larsson et al., 2004, Ng and Luo, 2004, Yang and Kunes, 2004, Carhan et al., 2004, Davidson et al., 2005, Kuzin et al., 2005, Kuzin et al., 2005, Pascual et al., 2005, Taillebourg et al., 2005, Marin et al., 2005, Ting et al., 2005, Rosenzweig et al., 2005, Lee et al., 2005, Tsuda et al., 2005, Fishilevich and Vosshall, 2005, Ramaekers et al., 2005, Rawson et al., 2005, Chen et al., 2005, Orihara-Ono et al., 2005, Cenci and Gould, 2005, Denholm et al., 2005, Ditch et al., 2005, Wang and Struhl, 2005, Williams and Truman, 2005, Leyssen et al., 2005, Cole et al., 2005, Manoli et al., 2005, Nern et al., 2005, Hsiung et al., 2005, Fishilevich et al., 2005, Mirth et al., 2005, Fan et al., 2005, Rodriguez Moncalvo and Campos, 2005, Sanchez-Soriano et al., 2005, Sykes and Condron, 2005, Brown et al., 2006, Monier et al., 2005, Zheng et al., 2006, Sokol and Ambros, 2005, Kimura et al., 2005, Kuo et al., 2005, Masuda-Nakagawa et al., 2005, Inoshita and Tanimura, 2006, Goldstein, 2005, Rawson, 2005)
      Cytology
      hide Phenotypic Data
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      hide Detailed Description
      Statement
      Reference
      Causes no toxicity throughout a cell's life.
      Expression of Mmus\Cd8aScer\UAS.T:Avic\GFP under the control of Scer\GAL4C96 does not result in any wing defects. Expression of Mmus\Cd8aScer\UAS.T:Avic\GFP under the control of Scer\GAL4hs.2sev or Scer\GAL4GMR.PF does not have any effect on the eye. Animals expressing Mmus\Cd8aScer\UAS.T:Avic\GFP under the control of Scer\GAL4pnr-MD237 show wild type bristle formation.
      Expression of Mmus\Cd8aScer\UAS.T:Avic\GFP under the control of Scer\GAL4CY2 in the follicle cells does not result in a mutant chorion phenotype.
      hide Interactions
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      hideNOT Suppressor of
      Statement
      Reference
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      Statement
      Reference
      hide Xenogenetic Interactions
      Statement
      Reference
      The border follicle cell migration defect seen in egg chambers expressing PvrDN.Scer\UAS under the control of Scer\GAL4slbo.2.6 is not suppressed by coexpression of Mmus\Cd8aScer\UAS.T:Avic\GFP. The border follicle cell migration defect seen in egg chambers expressing Rac1N17.Scer\UAS under the control of Scer\GAL4slbo.2.6 is not suppressed by coexpression of Mmus\Cd8aScer\UAS.T:Avic\GFP.
      hide Complementation & Rescue Data
      Comments
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      Bloomington
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      Discoverer
      hide Synonyms & Secondary IDs ( 3 )
      Reported As
      Symbol Synonym
      Mmus\Cd8aScer\UAS.T:Avic\GFP
       
      Mus\Cd8aScer\UAS.T:Avic\GFP
       
      UAS-mCD8-GFP
      Name Synonym
      Secondary FlyBase IDs
        hide References ( 251 )
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        hide Recent research papers ( 66 )
        Assa-Kunik et al., 2007, Development 134(6): 1161--1169
        Drosophila follicle cells are patterned by multiple levels of Notch signaling and antagonism between the Notch and JAK/STAT pathways. [FBrf0195377]
        Augustin et al., 2007, J. Neurosci. 27(1): 111--123
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        Bello et al., 2007, Development 134(6): 1091--1099
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        Bianco et al., 2007, Nature 448(7151): 362--365
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        Ebacher et al., 2007, Fly 1(2): 86--94
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        Jefferis et al., 2007, Cell 128(6): 1187--1203
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        Jones et al., 2007, Nature 445(7123): 86--90
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        Komiyama, 2007, Cell 128(2): 399--410
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        Kurtovic et al., 2007, Nature 446(7135): 542--546
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        Lin et al., 2007, Cell 128(6): 1205--1217
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        Liu et al., 2007, Nature 450(7167): 294--298
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        Thomas and van Meyel, 2007, Development 134(3): 591--600
        The glycosyltransferase Fringe promotes Delta-Notch signaling between neurons and glia, and is required for subtype-specific glial gene expression. [FBrf0192828]
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        Ashraf et al., 2006, Cell 124(1): 191--205
        Synaptic protein synthesis associated with memory is regulated by the RISC pathway in Drosophila. [FBrf0189896]
        Basto et al., 2006, Cell 125(4): 1375--1386
        Flies without centrioles. [FBrf0193251]
        Bello et al., 2006, Development 133(14): 2639--2648
        The brain tumor gene negatively regulates neural progenitor cell proliferation in the larval central brain of Drosophila. [FBrf0194745]
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        Bernard et al., 2006, Dev. Biol. 295(1): 164--177
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        Choi et al., 2006, Development 133(11): 2223--2232
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        Inoshita and Tanimura, 2006, Proc. Natl. Acad. Sci. USA 103(4): 1094--1099
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        Lee et al., 2006, Proc. Natl. Acad. Sci. USA 103(33): 12580--12585
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        Li et al., 2006, Genes Dev. 20(20): 2793--2805
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        Mahr and Aberle, 2006, Gene Expression Patterns 6(3): 299--309
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        McDonald et al., 2006, Dev. Biol. 296(1): 94--103
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        A signaling network for patterning of neuronal connectivity in the Drosophila brain. [FBrf0192599]
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        Zheng et al., 2006, EMBO J. 25(3): 615--627
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        Zhu et al., 2006, Cell 127(2): 409--422
        Gradients of the Drosophila Chinmo BTB-zinc finger protein govern neuronal temporal identity. [FBrf0194848]
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