Expression of B-H2 2.2kb cDNA is governed by UAS regulatory sequences.
visible, with Scer\GAL4ap-md544
visible, with Scer\GAL4ey.PB
eye, with Scer\GAL4ey.PB
leg, with Scer\GAL4ap-md544
morphogenetic furrow, with Scer\GAL4dpp.blk1
photoreceptor cell, with Scer\GAL4dpp.blk1
ventral thoracic disc, with Scer\GAL4dpp.blk1
When B-H2Scer\UAS.cSa is driven by Scer\GAL4lz-gal4 in the eye disc, furrow migration is blocked and photoreceptor differentiation is eliminated.
Expression of B-H2Scer\UAS.cSa under the control of Scer\GAL4ey.PB results in deletion of the eye.
Expression of B-H2Scer\UAS.cSa under the control of Scer\GAL4dpp.blk1 blocks furrow formation in the eye disc.
Overexpression of B-H2Scer\UAS.cSa under the control of Scer\GAL4dpp.blk1 results in ectopic fold formation in the leg disc. The formation of the endogenous central fold is interrupted. Overexpression of B-H2Scer\UAS.cSa under the control of Scer\GAL4ap-md544 gives similar leg phenotypes to those seen when B-H1Scer\UAS.cSa is expressed under the control of Scer\GAL4ap-md544.
B-H2UAS.cSa/Scer\GAL4lz-gal4 partially rescues Df(1)B
Scer\GAL4B-H1.B4.5.B-H2.S8/B-H2UAS.cSa partially rescues Df(1)BH2
Scer\GAL4B-H1.B4.5.B-H2.S8-driven expression of B-H2Scer\UAS.cSa rescues the microchaetae phenotype but not the PS macrochaetae phenotype of Df(1)BH2.