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General Information
Symbol
Dmel\sensE58
Species
D. melanogaster
Name
FlyBase ID
FBal0098020
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Nature of the Allele
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference

Scer\UAS regulatory sequences drive expression of sens sequences which include the sens 3'UTR.

Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In

abdominal dorsal multidendritic neuron ddaE & dendrite

dorsal multidendritic neuron ddaE & dendrite

Detailed Description
Statement
Reference

In sensE58 mutants, one of the dorsal class I neurons is missing in most hemisegments. In the remaining class I neurons, dendrites overextend dorsally and the arbors of ddaD and ddaE neurons are often mixed.

Heterozygotes do not show a loss of wing margin phenotype.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Suppressor of
Statement
Reference

sensE58/sens[+] is a suppressor | partially of visible phenotype of mir-9aJ22

Phenotype Manifest In
Suppressor of
Statement
Reference
Additional Comments
Genetic Interactions
Statement
Reference

Heterozygosity for sensE58 partially suppresses the supernumerary thoracic sensory bristle phenotype of individuals expressing Rbfox1dsRNA.Scer\UAS under the control of Scer\GAL4sca-109-68.

The presence of the sensE58/+ mutation partially rescues the supernumerary bristle phenotype of TBPHQ367X/TBPHQ367X mutants.

One copy of sensE58 substantially rescues the wing margin defects of mir-9aJ22 homozygotes; about 30% of the double mutant flies have wings that are indistinguishable from wild type, while others lack only a small part of the posterior margin. The bristles on the anterior wing margin resemble wild type in the double mutant flies.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Images (0)
Mutant
Wild-type
Stocks (2)
Notes on Origin
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (6)
Reported As
Name Synonyms
Secondary FlyBase IDs
    References (8)