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General Information
Symbol
Dmel\sensE1
Species
D. melanogaster
Name
FlyBase ID
FBal0098024
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Nature of the Allele
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

When somatic clones of sensE2/sensE1 in the eye are made in a Minute background, normally constructed ommatidia containing photoreceptors mutant for sens can only form if the R8 photoreceptor had at least one functional copy of sens. Large patches of mutant ommatidia are readily recovered in adults. These clones are disorganised and of variable size. The number of ommatidia and the spacing between them is not changed from the surrounding wild-type tissue. However all ommatidia have a striking similarity: they do not contain a discernable R8 or R7 photoreceptors.

Heterozygotes do not show a loss of wing margin phenotype.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Suppressed by
Enhancer of
Statement
Reference

sensE1/sensm1 is an enhancer of scutellar bristle | heat sensitive phenotype of sc1

sensE1/sensm2 is an enhancer of scutellar bristle | heat sensitive phenotype of sc1

sensE1/sensm1m2 is an enhancer of scutellar bristle | heat sensitive phenotype of sc1

Suppressor of
Statement
Reference

sensE1 is a suppressor | somatic clone of axon & photoreceptor cell R7 | somatic clone phenotype of Nf-YC40

sensE1/sens[+] is a suppressor | partially of macrochaeta & wing | ectopic phenotype of Mmus\Neurog1bato.UAS, Scer\GAL4dpp.blk1

sensE1/sens[+] is a suppressor | partially of macrochaeta & wing | ectopic phenotype of Mmus\Atoh1UAS.cQa, Scer\GAL4cv-c-C5/Scer\GAL4C5

Additional Comments
Genetic Interactions
Statement
Reference

The mis-targeting of Nf-YC40 R7 neurons to the M3 layer of the medulla is completely suppressed by sensE1.

The addition of rox63 suppresses the photoreceptor cell R8 phenotype seen in sensE2/sensE1 somatic clones.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (6)
Reported As
Name Synonyms
Secondary FlyBase IDs
    References (12)