Allele Dmel\kcc^Ad-4

General Information
Symbol	Dmel\kcc^Ad-4	Species	D. melanogaster
Name		FlyBase ID	FBal0098080
Feature type	allele	Associated gene	Dmel\kcc

Allele class
Mutagen	ethyl methanesulfonate
Recent Updates
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FB2013_03
FB2013_02
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Nature of the Allele
Allele class
Mutagen	ethyl methanesulfonate (Reed, 1992, Wharton et al., 1999)
Mutations Mapped to the Genome

Type Location Additional Notes References
Associated Sequence Data
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name

UniProtKB/Swiss-Prot
UniProtKB/TrEMBL

Progenitor genotype
Nature of the lesion	Statement Reference
Cytology
Phenotypic Data
Phenotypic Class
	bang sensitive (with kcc^DHS1) (Hekmat-Scafe et al., 2006) bang sensitive (with kcc^ML1) (Hekmat-Scafe et al., 2006) lethal (with kcc^EY08304) (Hekmat-Scafe et al., 2006) lethal (with kcc^P20-180) (Hekmat-Scafe et al., 2006) lethal \| recessive (Reed, 1992, Hekmat-Scafe et al., 2006)
Phenotype Manifest In

Detailed Description
	Statement Reference kcc[Ad-4]/kcc[DHS1] adults have a low penetrance (15%) bang sensitive phenotype. This phenotype is seen at a higher penetrance (34%) in kcc[Ad-4]/kcc[ML1] adults. (Hekmat-Scafe et al., 2006)
External Data
Linkouts
Interactions
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement Reference
Xenogenetic Interactions
Statement Reference
Complementation & Rescue Data
Comments
Stocks ( 2 )
Bloomington	5207 dp^ov1 cn¹ bw¹ kcc^Ad-4/SM6a
Kyoto	108098 dp^ov1 cn¹ bw¹ kcc^Ad-4/SM6a
Notes on Origin
Discoverer

External Crossreferences & Linkouts
Other Crossreferences

Linkouts

Synonyms & Secondary IDs ( 5 )
Reported As
Symbol Synonym	kcc^Ad-4 l(2)60A-C^Ad-4 l(2)60A-C^Ad4 (Hekmat-Scafe et al., 2006) l(2)Ad-4 (Reed, 1992) unnamed (Wharton et al., 1999)
Name Synonym
Secondary FlyBase IDs

References ( 4 )
Research paper	Hekmat-Scafe et al., 2006, J. Neurosci. 26(35): 8943--8954 Mutations in the K+/Cl- cotransporter gene kazachoc (kcc) increase seizure susceptibility in Drosophila. [FBrf0192588] Wharton et al., 1999, Genetics 152(2): 629--640 Genetic analysis of the bone morphogenetic protein-related gene, gbb, identifies multiple requirements during Drosophila development. [FBrf0109147]
Personal communication to FlyBase	Bloomington Drosophila Stock Center, 1999.6.22, Wharton 59F8;60A7 complementation groups. Wharton 59F8;60A7 complementation groups. [FBrf0108611]
Thesis	Reed, 1992, Ph.D. Thesis, University of Cambridge, England: 292pp The genetic analysis of endoreduplication in Drosophila melanogaster. [FBrf0064297]

Allele Dmel\kccAd-4

Allele Dmel\kcc^Ad-4