FlyBase Allele Report: Dmel\Ntf-2[G0428]

General Information

Symbol

Dmel\Ntf-2^G0428

Species

D. melanogaster

Name

FlyBase ID

FBal0098094

Feature type

allele

Associated gene

Dmel\Ntf-2

Associated Insertion(s)

P{lacW}Ntf-2^G0428

Carried in Construct

Key Links

Genomic Maps

JBrowse

Allele class

Mutagen

P-element activity

Nature of the Allele

Allele class

Mutagen

P-element activity

(Schäfer et al., 1999.6.15)

Progenitor genotype

Associated Insertion(s)

P{lacW}Ntf-2^G0428

Cytology

Description

P{lacW} is inserted 5 bases upstream of the annotated Ntf-2 transcription start site.

(Bhattacharya and Steward, 2002)

Allele components

Component

Use(s)

Inserted element

P{lacW}

enhancer trap

Encoded product / tool

lacZ

reporter enzyme

Tagged with

Tag:NLS(P)

nuclear protein localization tag

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

transposable_element_insertion_site

X:21,035,503..21,035,689 [+]

(Bhattacharya and Steward, 2002, Peter et al., 2002, Schäfer et al., 1999.6.15)

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

AJ427033

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

lethal | recessive

(Schäfer et al., 1999.6.15)

lethal - all die before end of larval stage | recessive

(Bhattacharya and Steward, 2002)

lethal - all die during embryonic stage

(Peter et al., 2002)

some die during embryonic stage

(Peter et al., 2002)

some die during third instar larval stage | recessive

(Bhattacharya and Steward, 2002)

Phenotype Manifest In

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Rescued by

Ntf-2^G0428 is rescued by Scer\GAL4^arm.PS/Ntf-2^UASp.GFP

(Bhattacharya and Steward, 2002)

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

Bloomington

11913

w^67c23 P{lacW}Ntf-2^G0428/FM7c, sn⁺

Notes on Origin

Discoverer

Comments

P{lacW} not verified as causing the lethality.

(Schäfer et al., 1999.6.15)

Excision of the P-element is accompanied by reversion of the mutant phenotype.

(Bhattacharya and Steward, 2002)

External Crossreferences and Linkouts ( 1 )

Crossreferences

GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.

AJ427033

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

Ntf-2^G0428

l(1)G0428

(Peter et al., 2002)

l(1)G0428^G0428

(Schäfer et al., 1999.6.15)

Name Synonyms

Secondary FlyBase IDs

References (3)

Report Sections

Open Close