FB2025_01 , released February 20, 2025
Allele: Dmel\Su(dx)32
Open Close
General Information
Symbol
Dmel\Su(dx)32
Species
D. melanogaster
Name
FlyBase ID
FBal0098291
Feature type
allele
Associated gene
Dmel\Su(dx)
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Progenitor genotype
    Cytology
    Description

    Rearrangement within the Su(dx) coding region.

    (Cornell et al., 1999)
    Mutations Mapped to the Genome
    Curation Data
    Type
    Location
    Additional Notes
    References
    sequence_variant
    2L:2,041,212..2,042,195 [+]
    Linked to:
    PstI-PstI restriction fragment
    Comment:

    rearrangement detected in PstI fragment;position of restriction fragment on reference sequence inferred by FlyBase curator

    (Cornell et al., 1999)
    Variant Molecular Consequences
    Associated Sequence Data
    DDBJ / EMBL / GenBank
    DNA sequence
    Protein sequence
     
    UniProtKB/Swiss-Prot
      UniProtKB/TrEMBL
        Expression Data
        Reporter Expression
        Additional Information
        Statement
        Reference
         
        Marker for
        Reflects expression of
        Reporter construct used in assay
        Human Disease Associations
        Disease Ontology (DO) Annotations
        Models Based on Experimental Evidence ( 0 )
        Disease
        Evidence
        References
        Modifiers Based on Experimental Evidence ( 0 )
        Disease
        Interaction
        References
        Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
         
        Disease-implicated variant(s)
         
        Phenotypic Data
        Phenotypic Class
        Phenotype Manifest In
        Detailed Description
        Statement
        Reference

        Shows a recessive forked cross-vein phenotype at 25oC. Heterozygotes with Df(2L)Su(dx)-7 eclose at 29oC with a wing vein gap phenotype.

        (Cornell et al., 1999)
        External Data
        Interactions
        Show genetic interaction network for Enhancers & Suppressors
        Phenotypic Class
        Enhancer of
        Statement
        Reference

        Su(dx)[+]/Su(dx)32 is an enhancer of chemical sensitive | adult stage phenotype of Otud6C183A

        (Villa et al., 2024)

        Su(dx)[+]/Su(dx)32 is an enhancer of increased mortality | adult stage phenotype of Otud6C183A

        (Villa et al., 2024)
        Other
        Phenotype Manifest In
        Additional Comments
        Genetic Interactions
        Statement
        Reference

        Rescues the lethality of Nnd-1 dxS1M/Y; Su(dx)sp/+ flies. Nnd-1/+, Su(dx)sp/Su(dx)32 shows a longitudinal vein gap phenotype.

        (Cornell et al., 1999)
        Xenogenetic Interactions
        Statement
        Reference
        Complementation and Rescue Data
        Fails to complement

        Su(dx)sp

        (Cornell et al., 1999)
        Rescued by

        Su(dx)32 is rescued by Su(dx)UAS.cCa/Scer\GAL4Bx-MS1096

        (Cornell et al., 1999)
        Comments
        Images (0)
        Mutant
        Wild-type
        Stocks (1)
        Notes on Origin
        Discoverer

        Separable from: a second site temperature-dependent lethality.

        (Cornell et al., 1999)
        External Crossreferences and Linkouts ( 0 )
        Synonyms and Secondary IDs (1)
        Reported As
        Symbol Synonym
        Su(dx)32
        (Villa et al., 2024, Ribot et al., 2022, Zhu et al., 2017, Shimizu et al., 2014, Djiane et al., 2011)
        Name Synonyms
        Secondary FlyBase IDs
          References (6)