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General Information
Symbol
Dmel\PTP-ERXE-2776
Species
D. melanogaster
Name
FlyBase ID
FBal0098355
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Mutations Mapped to the Genome
     
    Type
    Location
    Additional Notes
    References
    Associated Sequence Data
    DNA sequence
    Protein sequence
     
     
    Progenitor genotype
    Cytology
    Nature of the lesion
    Statement
    Reference
    Inversion breakpoint in the catalytic domain of PTP-ER.
    Caused by aberration
    Expression Data
    Reporter Expression
    Additional Information
    Statement
    Reference
     
    Marker for
    Reflects expression of
    Reporter construct used in assay
    Human Disease Associations
    Disease Ontology (DO) Annotations
    Models Based on Experimental Evidence ( 0 )
    Disease
    Evidence
    References
    Modifiers Based on Experimental Evidence ( 0 )
    Disease
    Interaction
    References
    Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
     
    Phenotypic Data
    Phenotypic Class
    Phenotype Manifest In
    Detailed Description
    Statement
    Reference
    Displays a very mild eye roughness due to the recruitment of ectopic R7 cells when hemizygous with a deficiency for the 57F--58A region.
    External Data
    Interactions
    Show genetic interaction network for Enhancers & Suppressors
    Phenotypic Class
    Enhancer of
    Statement
    Reference
    Suppressor of
    Statement
    Reference
    Phenotype Manifest In
    Enhanced by
    Enhancer of
    Suppressor of
    Statement
    Reference
    Additional Comments
    Genetic Interactions
    Statement
    Reference
    PTP-ERXE-3022/PTP-ERXE-2776 do not show synthetic lethality when placed in an alphS-331 homozygous background, however, a significant increase of extra R7 cells is observed compared to the respective single homozygotes.
    Enhancer of the Ras85DV12.sev rough eye phenotype. Heterozygous PTP-ERXE-2776 suppresses the rough eyes and loss of photoreceptor cells seen in either hemizygous Dsor1XS520, hemizygous phl12 or homozygous ksrS-548.
    Xenogenetic Interactions
    Statement
    Reference
    The neuronal degeneration phenotype and decreased survival of animals expressing Hsap\HDQ93.ex1p.Scer\UAS under the control of Scer\GAL4elav-C155 is partially suppressed in a PTP-ERXE-2776/+ background.
    Complementation and Rescue Data
    Comments
    Images (0)
    Mutant
    Wild-type
    Stocks (1)
    Notes on Origin
    Discoverer
    External Crossreferences and Linkouts ( 0 )
    Synonyms and Secondary IDs (1)
    Reported As
    Symbol Synonym
    Name Synonyms
    Secondary FlyBase IDs
      References (3)