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General Information
Symbol
Dmel\tgo5
Species
D. melanogaster
Name
FlyBase ID
FBal0098639
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Allele class
Mutagen
    Nature of the Allele
    Mutagen
    Mutations Mapped to the Genome
     
    Type
    Location
    Additional Notes
    References
    point mutation
    Nucleotide change:

    C9018281T

    Reported nucleotide change:

    C?T

    Amino acid change:

    Q468term | tgo-PA; Q468term | tgo-PB

    Reported amino acid change:

    Q468term

    Associated Sequence Data
    DNA sequence
    Protein sequence
     
     
    Progenitor genotype
    Cytology
    Nature of the lesion
    Statement
    Reference

    Nucleotide substitution: C1737T.

    Amino acid replacement: Q468term.

    Nucleotide substitution: A3049G.

    Expression Data
    Reporter Expression
    Additional Information
    Statement
    Reference
     
    Marker for
    Reflects expression of
    Reporter construct used in assay
    Human Disease Associations
    Disease Ontology (DO) Annotations
    Models Based on Experimental Evidence ( 0 )
    Disease
    Evidence
    References
    Modifiers Based on Experimental Evidence ( 0 )
    Disease
    Interaction
    References
    Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
     
    Phenotypic Data
    Phenotypic Class
    Phenotype Manifest In
    Detailed Description
    Statement
    Reference

    tgo5 clones (generated using the MARCM technique) of the ddaD and ddaC neurons do not show any obvious dendritic defects.

    Mutant embryos have tracheal defects.

    Close to a null allele. Homozygous clones have no effect in the proximal antennal segments (segments 1 and 2). Clones transform the distal part of antennal segment 3, the basal cylinder and arista to a tarsus that is deleted for most of its segments. Arista-claw intermediates are often present, and the identity of the proximal part of antennal segment 3 is unaffected. Homozygous clones in the distal part of the leg often show pattern deletions that include the second through fourth tarsal segments. Clones in the proximal part of the leg have no effect. Homozygous clones in the maxillary palps result in distal deletions. Homozygous clones in the wing hinge region cause the wing to be held out away from the body. Homozygous clones show a strong reduction in bristle size. Homozygous clones in the proboscis, vibrissae, dorsal head, dorsal thorax, wings and abdomen appear normal, with the exception of a reduction in bristle size.

    External Data
    Interactions
    Show genetic interaction network for Enhancers & Suppressors
    Phenotypic Class
    Phenotype Manifest In
    Suppressor of
    Statement
    Reference
    Other
    Additional Comments
    Genetic Interactions
    Statement
    Reference

    Dominant enhancer of the Df(3R)ss-D114.4/+ weak antenna to tarsus transformation phenotype. The antennae from Df(3R)ss-D114.4/tgo5 heterozygotes have a swelling at the base of the arista and bracted bristles on the basal cylinder and the distal part of antennal segment 3.

    Xenogenetic Interactions
    Statement
    Reference
    Complementation and Rescue Data
    Images (0)
    Mutant
    Wild-type
    Stocks (1)
    Notes on Origin
    Discoverer

    Selected as: a dominant enhancer of the Df(3R)ss-D114.4/+ weak antenna to tarsus transformation phenotype.

    External Crossreferences and Linkouts ( 0 )
    Synonyms and Secondary IDs (1)
    Reported As
    Name Synonyms
    Secondary FlyBase IDs
      References (8)