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General Information
Symbol
Dmel\aosUAS.cMa
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct a of Michelson
FlyBase ID
FBal0098779
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
UAS-Argos, UAS-aos
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference

UAS regulatory sequences drive expression of aos.

Allele components
Product class / Tool use(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Overexpression of aosScer\UAS.cMa under the control of Scer\GAL4Bx-MS1096 results in variable loss of dorsal longitudinal wing veins including L3.

Expression of aosScer\UAS.cMa using Scer\GAL4Bx-MS1096 results in an abnormally small wing with missing veins.

Flies expressing argosScer\UAS.cMa under the control of Scer\GAL4dpp.blk1 lack crossveins and have a gap in vein L3.

Expression of argosScer\UAS.cMa under the control of Scer\GAL4Bx-MS1096 results in wing vein loss and a small wing phenotype.

Expression of argosScer\UAS.cMa under the control of Scer\GAL41151 does not affect founder cell formation of patterning.

Expression of argosScer\UAS.cMa in border cells, driven by Scer\GAL4slbo.2.6 does not affect the formation of the egg chamber apical cap or the migration of the border cell cluster to the oocyte.

Expression of two copies of argosScer\UAS.cMa under the control of Scer\GAL4en-e16E results in wings which lack vein L4 and both crossveins. Expression of one copy of argosScer\UAS.cMa under the control of Scer\GAL4en-e16E results in a milder wing vein loss phenotype.

When argosScer\UAS.cMa is driven by Scer\GAL4hs.PB and heatshocked between 14 and 15 hours after puparium formation, a severe reduction is seen in numbers of antennal glia.

argosScer\UAS.cMa with Scer\GAL4pnr-MD237, Scer\GAL4426 or Scer\GAL4Gug-AGiR does not affect wing disc development. argosScer\UAS.cMa with Scer\GAL4ap-md544 or Scer\GAL4tsh-md621 causes severe reduction in notum tissue in the 3rd instar wing disc; however, no transformation of notum to wing fate is observed in these discs. argosScer\UAS.cMa; Scer\GAL4Ubx-lac1-Gal4adults exhibit wing duplication in the posterior compartment and partial loss of notum and/or hinge. Occasionally pharate adults die within the pupal case, with severe loss of notum tissue. In larvae of this genotype, the wing discs show altered morphology, particularly overgrowth in the posterior hinge and mesonotum. Marker analysis indicates formation a new wing pouch complete with the DV boundary, and that pattern duplication is associated with loss of notum, confirming notum/hinge-to-wing transformations.

Flies expressing argosScer\UAS.cMa under the control of Scer\GAL4Dll-md23 lack the pretarsus (including the claw). Tarsal segment 5 is reduced.

Shows a rough eye phenotype when crossed to an (unspecified) eye disk Scer\GAL4 driver.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Enhanced by
Statement
Reference

Scer\GAL4Bx-MS1096, aosUAS.cMa has visible phenotype, enhanceable by E-2g[+]/ebi2g1

Scer\GAL4Bx-MS1096, aosUAS.cMa has visible phenotype, enhanceable by E-3c77/E-3c7[+]

Scer\GAL4Bx-MS1096, aosUAS.cMa has visible phenotype, enhanceable by RpL38[+]/RpL382b1

Scer\GAL4Bx-MS1096, aosUAS.cMa has visible phenotype, enhanceable by RpL38[+]/RpL382b2

Scer\GAL4Bx-MS1096, aosUAS.cMa has visible phenotype, enhanceable by RpL52d1/RpL5[+]

Scer\GAL4Bx-MS1096, aosUAS.cMa has visible phenotype, enhanceable by RpL52d2/RpL5[+]

Scer\GAL4Bx-MS1096, aosUAS.cMa has visible phenotype, enhanceable by lep3c5/lep[+]

Scer\GAL4Bx-MS1096, aosUAS.cMa has visible phenotype, enhanceable by E-2g[+]/ebi2g2

Scer\GAL4Bx-MS1096, aosUAS.cMa has visible phenotype, enhanceable by lep3c6/lep[+]

Scer\GAL4Bx-MS1096, aosUAS.cMa has visible phenotype, enhanceable by ncm2a2/ncm[+]

Scer\GAL4Bx-MS1096, aosUAS.cMa has visible phenotype, enhanceable by pix3c2/pix[+]

Scer\GAL4Bx-MS1096, aosUAS.cMa has visible phenotype, enhanceable by pix3c3/pix[+]

Scer\GAL4Bx-MS1096, aosUAS.cMa has visible phenotype, enhanceable by prp8[+]/Prp82e1

Scer\GAL4Bx-MS1096, aosUAS.cMa has visible phenotype, enhanceable by Prp82e2/prp8[+]

Scer\GAL4Bx-MS1096, aosUAS.cMa has visible phenotype, enhanceable by ncm[+]/ncm2a1

Scer\GAL4Bx-MS1096, aosUAS.cMa has visible phenotype, enhanceable by E-3c1[+]/E-3c11

Scer\GAL4Bx-MS1096, aosUAS.cMa has visible phenotype, enhanceable by E-3c4[+]/E-3c44

NOT Enhanced by
Statement
Reference

Scer\GAL4Bx-MS1096, aosUAS.cMa has size defective phenotype, non-enhanceable by ebi[+]/ebiP7

Suppressed by
NOT suppressed by
Statement
Reference
Suppressor of
Statement
Reference
Other
Statement
Reference
Phenotype Manifest In
Enhanced by
Statement
Reference

Scer\GAL4Bx-MS1096, aosUAS.cMa has wing vein phenotype, enhanceable by ebiE90/ebi[+]

Scer\GAL4Bx-MS1096, aosUAS.cMa has wing vein phenotype, enhanceable by ebi[+]/ebiCC3

Scer\GAL4Bx-MS1096, aosUAS.cMa has wing vein phenotype, enhanceable by ebi[+]/ebiE4

Scer\GAL4Bx-MS1096, aosUAS.cMa has wing vein phenotype, enhanceable by ebiΔ1/ebi[+]

Scer\GAL4Bx-MS1096, aosUAS.cMa has wing phenotype, enhanceable by E-3c4[+]/E-3c44

Scer\GAL4Bx-MS1096, aosUAS.cMa has wing phenotype, enhanceable by E-3c77/E-3c7[+]

Scer\GAL4Bx-MS1096, aosUAS.cMa has wing phenotype, enhanceable by RpL38[+]/RpL382b1

Scer\GAL4Bx-MS1096, aosUAS.cMa has wing phenotype, enhanceable by E-2g[+]/ebi2g1

Scer\GAL4Bx-MS1096, aosUAS.cMa has wing phenotype, enhanceable by RpL38[+]/RpL382b2

Scer\GAL4Bx-MS1096, aosUAS.cMa has wing phenotype, enhanceable by RpL52d1/RpL5[+]

Scer\GAL4Bx-MS1096, aosUAS.cMa has wing phenotype, enhanceable by RpL52d2/RpL5[+]

Scer\GAL4Bx-MS1096, aosUAS.cMa has wing phenotype, enhanceable by lep3c5/lep[+]

Scer\GAL4Bx-MS1096, aosUAS.cMa has wing phenotype, enhanceable by lep3c6/lep[+]

Scer\GAL4Bx-MS1096, aosUAS.cMa has wing phenotype, enhanceable by ncm2a2/ncm[+]

Scer\GAL4Bx-MS1096, aosUAS.cMa has wing phenotype, enhanceable by pix3c2/pix[+]

Scer\GAL4Bx-MS1096, aosUAS.cMa has wing phenotype, enhanceable by pix3c3/pix[+]

Scer\GAL4Bx-MS1096, aosUAS.cMa has wing phenotype, enhanceable by prp8[+]/Prp82e1

Scer\GAL4Bx-MS1096, aosUAS.cMa has wing phenotype, enhanceable by Prp82e2/prp8[+]

Scer\GAL4Bx-MS1096, aosUAS.cMa has wing phenotype, enhanceable by E-2g[+]/ebi2g2

Scer\GAL4Bx-MS1096, aosUAS.cMa has wing phenotype, enhanceable by ncm[+]/ncm2a1

Scer\GAL4Bx-MS1096, aosUAS.cMa has wing vein phenotype, enhanceable by E-3c1[+]/E-3c11

Scer\GAL4Bx-MS1096, aosUAS.cMa has wing phenotype, enhanceable by E-3c1[+]/E-3c11

NOT Enhanced by
Statement
Reference

Scer\GAL4Bx-MS1096, aosUAS.cMa has wing vein phenotype, non-enhanceable by ebi[+]/ebik16213

Scer\GAL4Bx-MS1096, aosUAS.cMa has wing vein phenotype, non-enhanceable by ebi[+]/ebiWKS-24

Scer\GAL4Bx-MS1096, aosUAS.cMa has wing vein phenotype, non-enhanceable by ebi[+]/ebiP7

Scer\GAL4Bx-MS1096, aosUAS.cMa has wing vein phenotype, non-enhanceable by E-3c4[+]/E-3c44

Scer\GAL4Bx-MS1096, aosUAS.cMa has wing vein phenotype, non-enhanceable by E-3c77/E-3c7[+]

Scer\GAL4Bx-MS1096, aosUAS.cMa has wing vein phenotype, non-enhanceable by RpL38[+]/RpL382b1

Scer\GAL4Bx-MS1096, aosUAS.cMa has wing vein phenotype, non-enhanceable by RpL38[+]/RpL382b2

Scer\GAL4Bx-MS1096, aosUAS.cMa has wing vein phenotype, non-enhanceable by RpL52d1/RpL5[+]

Scer\GAL4Bx-MS1096, aosUAS.cMa has wing vein phenotype, non-enhanceable by RpL52d2/RpL5[+]

Scer\GAL4Bx-MS1096, aosUAS.cMa has wing vein phenotype, non-enhanceable by lep3c5/lep[+]

Scer\GAL4Bx-MS1096, aosUAS.cMa has wing vein phenotype, non-enhanceable by lep3c6/lep[+]

Scer\GAL4Bx-MS1096, aosUAS.cMa has wing vein phenotype, non-enhanceable by ncm2a2/ncm[+]

Scer\GAL4Bx-MS1096, aosUAS.cMa has wing vein phenotype, non-enhanceable by pix3c2/pix[+]

Scer\GAL4Bx-MS1096, aosUAS.cMa has wing vein phenotype, non-enhanceable by pix3c3/pix[+]

Scer\GAL4Bx-MS1096, aosUAS.cMa has wing vein phenotype, non-enhanceable by prp8[+]/Prp82e1

Scer\GAL4Bx-MS1096, aosUAS.cMa has wing vein phenotype, non-enhanceable by Prp82e2/prp8[+]

Scer\GAL4Bx-MS1096, aosUAS.cMa has wing vein phenotype, non-enhanceable by ncm[+]/ncm2a1

Suppressed by
NOT suppressed by
Statement
Reference
Suppressor of
Other
Statement
Reference
Additional Comments
Genetic Interactions
Statement
Reference

Overexpression of aosScer\UAS.cMa under the control of Scer\GAL4Bx-MS1096 in homozygous pk30 mutants induces partial loss of longitudinal wing veins. The discontinuity in hair and ridge orientation maps to the site of the L3 vein.

Heterozygosity for ebi2g2, ebiE90, ebiCC3, ebi2g1, ebiCCS-8, ebiE4, ebiΔ1 or ebiW418X enhances the small wing and wing vein loss phenotypes induced by Scer\GAL4Bx-MS1096-mediated expression of aosScer\UAS.cMa.

Expression of argosScer\UAS.cMa completely suppresses the haltere-to-wing transformation of Ubxlac1-GAL4/+ flies.

Co-expression of Socs44AScer\UAS.cRa partially suppresses the loss of wing vein phenotype that is seen in flies expressing two copies of argosScer\UAS.cMa under the control of Scer\GAL4en-e16E; the posterior crossvein and the most proximal and distal parts of wing vein L4 are restored.

Co-expression of one copy of Socs44AScer\UAS.cRa and one copy of argosScer\UAS.cMa under the control of Scer\GAL4en-e16E results in an almost wild-type wing.

The severity of the wing vein loss phenotype caused by expression of argosScer\UAS.cMa under the control of Scer\GAL4en-e16E is enhanced by Df(2R)CA53/+, but is not affected by Df(2R)Drlrv18/+.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (2)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (4)
Reported As
Symbol Synonym
aosScer\UAS.cMa
aosUAS.cMa
argosScer\UAS.cMa
Name Synonyms
Saccharomyces cerevisiae UAS construct a of Michelson
Secondary FlyBase IDs
    References (15)