Allele Scer\GAL4^fat

General Information
Symbol	Scer\GAL4^fat	Species	S. cerevisiae
Name		FlyBase ID	FBal0098822
Feature type	allele	Associated gene	Scer\GAL4

Allele class
Mutagen	P-element activity
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Nature of the Allele
Allele class
Mutagen	P-element activity (Maxton-Kuchenmeister et al., 1999)
Mutations Mapped to the Genome

Type Location Additional Notes References
Associated Sequence Data
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name

UniProtKB/Swiss-Prot
UniProtKB/TrEMBL

Progenitor genotype
Nature of the lesion	Statement Reference
Caused by insertion	P{GAL4}fat (Maxton-Kuchenmeister et al., 1999, Missirlis et al., 2006, Lind et al., 2006, Palanker et al., 2009, Hader et al., 2003, Scott et al., 2004, Scott et al., 2004, Gronke et al., 2003, Gronke, 2003, Gronke et al., 2005, Beller et al., 2006, Hennig et al., 2006, Wang et al., 2011, Shchedrina et al., 2009, Birner-Gruenberger et al., 2012, Scott et al., 2007, Arsham and Neufeld, 2009, Grönke et al., 2007, Liu et al., 2009, Kohyama-Koganeya et al., 2008, Grönke et al., 2009, Ballard et al., 2010, Wiklund et al., 2009, Beller et al., 2010, Zou et al., 2011, Lee et al., 2011, Missirlis et al., 2003, Rynes et al., 2012, Zhao et al., 2012)
Cytology
Phenotypic Data
Phenotypic Class
	lethal \| pupal stage, with adp^Scer\UAS.cHa (Hader et al., 2003) lethal \| pupal stage \| heat sensitive, with Aven^GD9098 (Zou et al., 2011) stress response defective, with Lsd-1^{dsRNA.Scer\UAS.cBa} (Beller et al., 2010) viable, with Irp-1A^Scer\UAS.cLa (Lind et al., 2006) viable, with Irp-1B^Scer\UAS.cLa (Lind et al., 2006)
Phenotype Manifest In
	adult fat body, with bmm^Scer\UAS.cGa (Gronke et al., 2005) adult fat body, with bmm^{Scer\UAS.T:Avic\GFP-EGFP} (Gronke et al., 2005) embryonic/larval fat body, with adp^Scer\UAS.cHa (Hader et al., 2003) embryonic/larval oenocyte, with InR^{K1409A.Scer\UAS} (Kohyama-Koganeya et al., 2008) fat body, with Atg5^{dsRNA.Scer\UAS} (Scott et al., 2004) fat body, with gbb^{dsRNA.Scer\UAS.cBa} (Ballard et al., 2010) fat body, with Lsd-2^Scer\UAS.cGa (Gronke et al., 2003) lipid droplet, with Akh^Scer\UAS.cLa (Grönke et al., 2007) lipid particle, with Lsd-1^{dsRNA.Scer\UAS.cBa} (Beller et al., 2010)
Detailed Description
	Statement Reference
External Data
Linkouts
Interactions
	Show the genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Suppressor of
Statement Reference Scer\GAL4^fat/Hsap\ATF3^{Scer\UAS.T:Zzzz\FLAG} is a suppressor \| partially of lethal phenotype of Atf3⁷⁶ (Rynes et al., 2012)
NOT Suppressor of
Statement Reference Scer\GAL4^fat/Hsap\PLIN1^Scer\UAS.cBa is a non-suppressor of large body phenotype of Lsd-1¹ (Beller et al., 2010)
Phenotype Manifest In
Suppressed by
Statement Reference Scer\GAL4^fat, bmm^Scer\UAS.cGa has phenotype, suppressible \| partially by Lsd-2^Scer\UAS.cGa, Scer\GAL4^fat (Gronke et al., 2005, Gronke et al., 2005)
Suppressor of
Statement Reference Lsd-2^Scer\UAS.cGa, Scer\GAL4^fat is a suppressor \| partially of phenotype of Scer\GAL4^fat, bmm^Scer\UAS.cGa (Gronke et al., 2005, Gronke et al., 2005) Scer\GAL4^fat/Hsap\ATF3^{Scer\UAS.T:Zzzz\FLAG} is a suppressor \| partially of lipid particle phenotype of Atf3⁷⁶ (Rynes et al., 2012)
NOT Suppressor of
Statement Reference Scer\GAL4^fat/Akh^Scer\UAS.cLa is a non-suppressor of lipid droplet phenotype of AkhR¹ (Grönke et al., 2007) Scer\GAL4^fat/Hsap\PLIN1^Scer\UAS.cBa is a non-suppressor of lipid particle phenotype of Lsd-1¹ (Beller et al., 2010)
Additional Comments
Genetic Interactions
Statement Reference
Xenogenetic Interactions
Statement Reference
Complementation & Rescue Data
Rescues	Scer\GAL4^fat/cu^{RC.Scer\UAS.T:Avic\GFP-EGFP} rescues cu³ (Grönke et al., 2009) Scer\GAL4^fat/gbb^Scer\UAS.cKa rescues gbb¹ (Ballard et al., 2010) Scer\GAL4^fat/Hnf4^Scer\UAS.cPa rescues Hnf4^Δ17/Hnf4^Δ33 (Palanker et al., 2009) Scer\GAL4^fat/Lsd-1^Scer\UAS.cBa rescues Lsd-1¹ (Beller et al., 2010) Scer\GAL4^fat/Lsd-2^Scer\UAS.cGa rescues Lsd-2^KG00149 (Gronke et al., 2003) Sik3^{Scer\UAS.T:Ivir\HA1}/Scer\GAL4^fat rescues Sik3⁴⁸ (Wang et al., 2011)
Fails to rescue	Scer\GAL4^fat/Sik3^{4A.Scer\UAS.T:Ivir\HA1} fails to rescue Sik3⁴⁸ (Wang et al., 2011) Scer\GAL4^fat/Sik3^{K70M.Scer\UAS.T:Ivir\HA1} fails to rescue Sik3⁴⁸ (Wang et al., 2011) Scer\GAL4^fat/Sik3^{T196A.Scer\UAS.T:Ivir\HA1} fails to rescue Sik3⁴⁸ (Wang et al., 2011)
Comments
Stocks ( 0 )

Notes on Origin
Discoverer

External Crossreferences & Linkouts
Other Crossreferences

Linkouts

Synonyms & Secondary IDs ( 2 )
Reported As
Symbol Synonym	fat body specific Gal4 driver (Gronke et al., 2003) Scer\GAL4^fat
Name Synonym
Secondary FlyBase IDs

References ( 30 )

Generate a list of	All references relating to this allele ( 30 )

List References by type	Research paper ( 26 ) Supplementary material ( 4 )
Recent research papers ( 6 )
	Birner-Gruenberger et al., 2012, Insect Biochem. Mol. Biol. 42(3): 220--229 Functional fat body proteomics and gene targeting reveal in vivo functions of Drosophila melanogaster α-Esterase-7. [FBrf0217320] Rynes et al., 2012, Mol. Cell. Biol. 32(19): 3949--3962 Activating transcription factor 3 regulates immune and metabolic homeostasis. [FBrf0219385] Zhao et al., 2012, J. Clin. Invest. 122(7): 2417--2427 Regulation of lipogenesis by cyclin-dependent kinase 8-mediated control of SREBP-1. [FBrf0218723] Lee et al., 2011, Dev. Biol. 356(2): 588--597 UVRAG is required for organ rotation by regulating Notch endocytosis in Drosophila. [FBrf0214470] Wang et al., 2011, Cell 145(4): 596--606 A hormone-dependent module regulating energy balance. [FBrf0213699] Zou et al., 2011, Cell Cycle 10(6): 989--998 Identification of dAven, a Drosophila melanogaster ortholog of the cell cycle regulator Aven. [FBrf0213442] Show all research papers ...

Allele Scer\GAL4fat

Allele Scer\GAL4^fat