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General Information
Symbol
Dmel\trcS066917a
Species
D. melanogaster
Name
FlyBase ID
FBal0100048
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
trc7, 0669/17, trcP
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference
P{lacW} insertion in the first intron.
Insertion components
P{lacW}trcS066917a
Product class / Tool use(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference
Mutant cells in trcS066917a large clones in the pupal wing often have an irregular shape, and their average cross-sectional area is ~1.6-fold larger than control neighboring cells. Hair morphogenesis is delayed in the trcS066917a mutant cells. trcS066917a mutants show a multiple wing hair phenotype. Expression of trcS292A.Scer\UAS under the control of Scer\GAL4ap-md544 in a trcS066917a/+ background enhances the multiple wing hair phenotype seen when trcS066917a is expressed in a wild-type background.
Homozygous second instar larvae have many split denticles per segment.
Hemizygous flies have branched arista laterals.
Homozygous clones have a multiple wing hair phenotype (5.74 hairs/cell).
Mutant cells in homozygous clones in the wing show a strong multiple hair cell phenotype. The number of hairs per cell varies between different clones from an average of 3.5 hairs per cell to more than 7 hairs per cell. Mutant cells in pupal wings have on average a weaker phenotype than clones in adult wings. A substantial number of cells in the clone in pupal wings do not have a multiple wing hair phenotype, in contrast to adult wings. When a wing cell produces a single hair in pupal clones, the hair appears to be the same length as neighbouring wild-type hairs. Only mutant cells show the multiple hair phenotype in pupal wings containing homozygous clones.
External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Suppressed by
Statement
Reference
Other
Statement
Reference
fry1/fry[+], matse03077, trc[+]/trcS066917a has visible | dominant phenotype
Phenotype Manifest In
Suppressed by
Other
Statement
Reference
Additional Comments
Genetic Interactions
Statement
Reference
fry1 trcS066917a matse03077 triple heterozygotes have a weak multiple wing hair phenotype in 40% of wings. The split denticle phenotype of matse03077 trcS066917a double mutant second instar larvae is no more severe than the split denticle phenotype of each single mutant.
trcS066917a fry1 double mutant clones do not have a stronger multiple wing hair phenotype (5.37 hairs/cell) than either single mutant.
Xenogenetic Interactions
Statement
Reference
Expression of Hsap\NDRG1Scer\UAS.cHa under the control of Scer\GAL4Act5C.PI rescues both the lethality and the multiple wing hair phenotype of trcS066917a mutants.
Complementation and Rescue Data
Images (0)
Mutant
Wild-type
Stocks (1)
Notes on Origin
Discoverer
Comments
Comments
Excision of the P{lacW} element can result in reversion of the phenotype.
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (6)
Reported As
Name Synonyms
Secondary FlyBase IDs
    References (9)