|Feature type||allele||Associated gene||Dmel\dome|
|Also Known As||l(1)G0441, dome441|
|Map ( GBrowse )||
|Allele class||loss of function allele|
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|Nature of the Allele|
|Mutations Mapped to the Genome|
|Associated Sequence Data|
|Nature of the lesion|
|Caused by insertion|
|Phenotype Manifest In|
Homozygous embryos have a posterior spiracle defect. Embryos derived from females containing homozygous germ-line clones die with segmentation defects. Both paternally rescued and non-rescued embryos show a consistent deletion of the 5th abdominal segment and the posterior midventral part of the 4th abdominal segment. Additional defects in the thoracic segments and head and tail regions are seen in paternally non-rescued embryos. Paternally rescued embryos derived from females containing homozygous germ-line clones form a defective tracheal system with several disruptions in the main trunk and many branches.
Mosaic egg chambers in which the border cells are domeG0441 show a lack of or defective border cell migration. In some mosaic egg chambers the border cell clusters are not formed or contain less cells than normal. In mosaic border cell clusters, the wild-type cells usually migrate normally or ahead of the domeG0441 cells.
Lethality occurs during the embryonic stage and the first larval instar.
The shape of the posterior spiracles is affected in mutants.
|Phenotype Manifest In|
domeG0441/dome[+] is a suppressor | partially of eye phenotype of Scer\GAL4GMR.PF/Scer\GAL4GMR.PF, osScer\UAS.cCa
|Complementation & Rescue Data|
|Stocks ( 1 )|
|Notes on Origin|
Mobilisation of the P-element reverts both the lethality and posterior spiracle phenotype.
|External Crossreferences & Linkouts|
|Synonyms & Secondary IDs ( 5 )|
|Secondary FlyBase IDs|
|References ( 7 )|
|Personal communication to FlyBase|