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General Information
Symbol
Dmel\MoeG0415
Species
D. melanogaster
Name
FlyBase ID
FBal0100274
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference
Insertion components
P{lacW}MoeG0415
Product class / Tool use(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference
Hemizygous third instar larvae have gaps in the laminar plexus. Abnormally thick axons bundles that project into the medulla and have abnormal wandering projections are seen. The growth cones in the medulla are enlarged and often overlap with each other.
60% of embryos from MoeEP1652/MoeG0415 mothers lack germ cells. In MoeEP1652/MoeG0415 oocytes, the actin cytoskeleton is detached from the cortex. Only 1% of embryos from MoeG0415/MoeGT193, mothers lack germ cells.
External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Partially rescued by
Comments
Expression of MoeK.Scer\UAS.T:Hsap\MYC under the control of Scer\GAL4elav.PU rescues the R2-R5 axon targeting defects seen in MoeG0415 hemizygotes in 55% of cases.
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
Comments
Comments
P{lacW} not verified as causing the lethality.
External Crossreferences and Linkouts ( 1 )
Crossreferences
GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.
Synonyms and Secondary IDs (6)
Reported As
Symbol Synonym
Name Synonyms
Secondary FlyBase IDs
    References (6)