FB2025_01 , released February 20, 2025
Allele: Dmel\nejG0350
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General Information
Symbol
Dmel\nejG0350
Species
D. melanogaster
Name
FlyBase ID
FBal0100311
Feature type
allele
Associated gene
Dmel\nej
Associated Insertion(s)
P{lacW}nejG0350
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
P-element activity
(Schäfer et al., 1999.8.12)
Progenitor genotype
Associated Insertion(s)
P{lacW}nejG0350
Cytology
Description
Allele components
Component
Use(s)
Inserted element
P{lacW}
Encoded product / tool
lacZ
Tagged with
Tag:NLS(P)
Mutations Mapped to the Genome
Curation Data
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
AJ426814
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      nejG0350/+ adults expressing Hsap\HOXA9::Hsap\NUP98WT.UAS under the control of Scer\GAL4ey.PH show ectopic wing-like structures in the dorsal-anterior part of the eye.

      (Gavory et al., 2021)

      Mutants show defects in destruction of the larval salivary glands, having persistant larval salivary glands at the pupal stage.

      (Wang et al., 2008)

      Mutants show developmental arrest soon after the prepupal-pupal transition. 70% of mutant pupae have persistent larval salivary glands. These glands do not show any morphological signs of tissue breakdown, showing tight cellular association at 13.5 and 16 hours after puparium formation.

      (Yin et al., 2007)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Enhancer of
      Phenotype Manifest In
      Enhancer of
      Statement
      Reference

      nej[+]/nejG0350 is an enhancer of eye phenotype of Hsap\HOXA9::Hsap\NUP98WT.UAS, Scer\GAL4ey.PH

      (Gavory et al., 2021)
      Other
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Fails to complement

      nejQ7

      (Yin et al., 2007)
      Partially rescued by

      nejG0350 is partially rescued by nejUAS.cYa/Scer\GAL4Sgs3.PD

      (Yin et al., 2007)
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      Comments
      Comments

      P{lacW} not verified as causing the lethality.

      (Schäfer et al., 1999.8.12)
      External Crossreferences and Linkouts ( 1 )
      Crossreferences
      GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.
      Synonyms and Secondary IDs (4)
      Reported As
      Symbol Synonym
      CBPG0350
      (Yin et al., 2007)
      l(1)G0350
      (Wang et al., 2008, Peter et al., 2002)
      l(1)G0350G0350
      nejG0350
      (Gavory et al., 2021)
      Name Synonyms
      Secondary FlyBase IDs
        References (5)