Open Close
General Information
Symbol
Dmel\MycP1
Species
D. melanogaster
Name
FlyBase ID
FBal0100371
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
dmycP1
Nature of the Allele
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference

Internal deletion of the P{P-Sal} element.

Insertion components
P{P-Sal-ΔP1}MycP1
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Approximately 23% of dmP0 homozygous females survive to adulthood, compared with 51% of sibling dm1/Y males.

Irradiation of mutant eye discs with 5 or 10 Gy results in fewer apoptotic cells than irradiation of wild-type discs, although irradiation of eye discs with 50 Gy results in a high number of apoptotic cells in both wild-type and mutant discs.

Homozygous pupae are more sensitive to X rays than wild type or heterozygous sibling controls.

Oogenesis in dmP1 homozygous females is arrested between stages 10 and 11.

Stronger phenotype than dmP0. Thin and shortened bristles. Small body size. Size of wing cells, wing width and wing length are reduced. Number of wing cells may also be reduced. Developmental rate is reduced and flies occasionally have small, roughened eyes. Dissociated wing disc cells are reduced in size compared to wild type. Twin spot analysis of mutant clones shows that dm mutant cells grow very poorly, particularly in the posterior compartment of the wing disc.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Suppressed by
Statement
Reference

MycP1 has lethal | female limited phenotype, suppressible | partially by scsisB-1

MycP1 has lethal | female limited phenotype, suppressible | partially by run3

NOT suppressed by
Statement
Reference

MycP1 has size defective phenotype, non-suppressible by agounspecified

Suppressor of
Statement
Reference

MycP1 is a suppressor | partially of viable phenotype of SxlfP7B0

Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference

Approximately 84% of sisAunspecified dmP1 trans-heterozygous female offspring from dmP1 fathers mated to sisAunspecified mothers survive.

Approximately 76% of scsisB-1 dmP1 trans-heterozygous female offspring from dmP1 fathers mated to scsisB-1 mothers survive.

Approximately 89% of run3 dmP1 trans-heterozygous female offspring from dmP1 fathers mated to run3 mothers survive.

Females trans-heterozygous for SxlfP7B0 and dmP1 are approximately two-thirds as viable as their dmP1/+ siblings.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
Comments
Comments

Alleles can be ranked in a phenotypic series. Going from weakest to strongest phenotype: dm1 < dmP0 < dmP1.

External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (4)
Reported As
Name Synonyms
Secondary FlyBase IDs
    References (7)