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General Information
Symbol
Dmel\Pi3K21BUAS.Δ.Tag:HA
Species
D. melanogaster
Name
FlyBase ID
FBal0100421
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
UAS-Δp60
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Carried in construct
Cytology
Nature of the lesion
Statement
Reference

Deletion of amino acids 466-558.

Allele components
Product class / Tool use(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Migration of about a fifth of ganglionic tracheal branches stalls in stage 16 Pi3K21BScer\UAS.Δ.T:Ivir\HA1; Scer\GAL4bs-23.26 embryos.

Caspase activation in cells posterior to the furrow in eye discs is only slightly reduced by Pi3K92EScer\UAS.T:Hsap\MYC; Scer\GAL4GMR.PF.

Expression of Pi3K21BScer\UAS.Δ.T:Ivir\HA1 under the control of Scer\GAL4Act5C.PP or Scer\GAL4Adh.PF inhibits larval growth. Clones of cells expressing Pi3K21BScer\UAS.Δ.T:Ivir\HA1 under the control of Scer\GAL4Act5C.PP in the salivary glands and fat body are greatly reduced in size and have much smaller nuclei with far less DNA than adjacent control cells. Expression of Pi3K21BScer\UAS.Δ.T:Ivir\HA1 under the control of Scer\GAL4Adh.PF, Scer\GAL4en-e16E or Scer\GAL4Act5C.PP has no effect on viability under starvation conditions.

Pi3K21BScer\UAS.Δ.T:Ivir\HA1 clones in the wing disc (driven by Scer\GAL4Act5C.PP) show a reduced cell size and delays in G1 progression. Clones have very few cells compared to controls.

When expression is driven is imaginal disc cells by Scer\GAL4Act5C.PP the size of the cells is reduced (as measured by FSC (forward scatter)). Cells are reduced in size in both G1 and S+G2. Overexpression of Pi3K21BScer\UAS.T:Ivir\HA1 or Pi3K21BScer\UAS.Δ.T:Ivir\HA1 is sufficient to reduce the rate of increase of cell number.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
Pi3K21BScer\UAS.Δ.T:Ivir\HA1
Pi3K21BUAS.Δ.Tag:HA
Name Synonyms
Secondary FlyBase IDs
    References (11)