Allele Dmel\H^Scer\UAS.cGb

General Information
Symbol	Dmel\H^Scer\UAS.cGb	Species	D. melanogaster
Name	Saccharomyces cerevisiae UAS construct a of Giebel	FlyBase ID	FBal0100424
Feature type	allele	Associated gene	Dmel\H

Allele class
Mutagen	in vitro construct - regulatory fusion
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Nature of the Allele
Allele class
Mutagen	in vitro construct - regulatory fusion (Giebel, 1999)
Mutations Mapped to the Genome

Type Location Additional Notes References
Associated Sequence Data
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name

UniProtKB/Swiss-Prot
UniProtKB/TrEMBL

Progenitor genotype
Nature of the lesion	Statement Reference Construct: The H coding region is driven by Scer\UAS regulatory sequences. (Giebel, 1999)
Carried in construct	P{UAS-H.Gb} (Giebel, 1999)
Cytology
Phenotypic Data
Phenotypic Class

Phenotype Manifest In
	embryonic/larval somatic muscle, with Scer\GAL4^da.G32 (Giebel, 1999) embryonic/larval somatic muscle, with Scer\GAL4^how-24B (Giebel, 1999) muscle founder cell, with Scer\GAL4^da.G32 (Giebel, 1999) muscle founder cell, with Scer\GAL4^how-24B (Giebel, 1999) peripheral nervous system, with Scer\GAL4^da.G32 (Giebel, 1999)
Detailed Description
	Statement Reference Expression of H^Scer\UAS.cGb driven by Scer\GAL4^da.G32 or Scer\GAL4^how-24B leads to a slight increase in number of muscle founder cells. This correlates with an increase in the number of differentiated muscle fibres. H^Scer\UAS.cGb driven by Scer\GAL4^da.G32 also leads to a weakly hyperplasic nervous system. (Giebel, 1999)
External Data
Linkouts
Interactions
	Show the genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Suppressor of
Statement Reference H^Scer\UAS.cGb, Scer\GAL4^da.G32 is a suppressor of central nervous system phenotype of N^{int.SH.Scer\UAS}, Scer\GAL4^da.G32 (Giebel, 1999) H^Scer\UAS.cGb, Scer\GAL4^da.G32 is a suppressor of embryonic/larval somatic muscle phenotype of N^{int.SH.Scer\UAS}, Scer\GAL4^da.G32 (Giebel, 1999) H^Scer\UAS.cGb, Scer\GAL4^da.G32 is a suppressor of muscle fiber phenotype of N^{int.SH.Scer\UAS}, Scer\GAL4^da.G32 (Giebel, 1999) H^Scer\UAS.cGb, Scer\GAL4^da.G32 is a suppressor of muscle founder cell phenotype of N^{int.SH.Scer\UAS}, Scer\GAL4^da.G32 (Giebel, 1999) H^Scer\UAS.cGb, Scer\GAL4^da.G32 is a suppressor of peripheral nervous system phenotype of N^{int.SH.Scer\UAS}, Scer\GAL4^da.G32 (Giebel, 1999) H^Scer\UAS.cGb, Scer\GAL4^how-24B/Scer\GAL4^how-24B is a suppressor of embryonic/larval somatic muscle phenotype of N^{int.SH.Scer\UAS}, Scer\GAL4^how-24B/Scer\GAL4^how-24B (Giebel, 1999) H^Scer\UAS.cGb, Scer\GAL4^how-24B/Scer\GAL4^how-24B is a suppressor of muscle fiber phenotype of N^{int.SH.Scer\UAS}, Scer\GAL4^how-24B/Scer\GAL4^how-24B (Giebel, 1999) H^Scer\UAS.cGb, Scer\GAL4^how-24B/Scer\GAL4^how-24B is a suppressor of muscle founder cell phenotype of N^{int.SH.Scer\UAS}, Scer\GAL4^how-24B/Scer\GAL4^how-24B (Giebel, 1999)
Additional Comments
Genetic Interactions
Statement Reference Co-expression of H^Scer\UAS.cGb and N^{int.SH.Scer\UAS} driven by Scer\GAL4^da.G32 or Scer\GAL4^how-24B produces embryos with fewer muscle founder cells than wild-type, but more than seen in embryos with N^{int.SH.Scer\UAS} alone (driven by Scer\GAL4^da.G32 or Scer\GAL4^how-24B) alone. Also well differentiated muscles are found, in contrast to N^{int.SH.Scer\UAS} alone. Co-expression of H^Scer\UAS.cGb and N^{int.SH.Scer\UAS} driven by Scer\GAL4^da.G32 CNS and some PNS structures are seen to differentiate in contrast to N^{int.SH.Scer\UAS} alone (driven by Scer\GAL4^da.G32). (Giebel, 1999)
Xenogenetic Interactions
Statement Reference
Complementation & Rescue Data
Comments
Stocks ( 0 )

Notes on Origin
Discoverer

External Crossreferences & Linkouts
Other Crossreferences

Linkouts

Synonyms & Secondary IDs ( 2 )
Reported As
Symbol Synonym	H^Scer\UAS.cGb
Name Synonym	Saccharomyces cerevisiae UAS construct a of Giebel (Giebel, 1999)
Secondary FlyBase IDs

References ( 1 )
Research paper	Giebel, 1999, Mech. Dev. 86(1-2): 137--145 The Notch signaling pathway is required to specify muscle progenitor cells in Drosophila. [FBrf0111372]

Allele Dmel\HScer\UAS.cGb

Allele Dmel\H^Scer\UAS.cGb