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General Information
Symbol
Dmel\E(spl)mα-BFMUAS.cAa
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct a of Apidianakis
FlyBase ID
FBal0101270
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
UAS-mα
Key Links
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference

The complete E(spl)mα-BFM cDNA is under the control of UASt sequences.

Allele components
Product class / Tool use(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In

dorsal row & sensory mother cell, with Scer\GAL4ap-md544

macrochaeta & scutum, with Scer\GAL4pnr-MD237

microchaeta & scutum, with Scer\GAL4pnr-MD237

Detailed Description
Statement
Reference

Expression of Scer\UAS.cAa under the control of Scer\GAL4ey.PB has no effect on either eye or antenna disc development.

Expression of Scer\UAS.cAa when driven by Scer\GAL4bi-omb-Gal4 in the wing disc leads to an increase in the numbers of sensory organ precursors seen.

Flies with Scer\UAS.cAa under the control of Scer\GAL4ptc-559.1, Scer\GAL4sca-T3, Scer\GAL4455.2, Scer\GAL4pnr-MD237 or Scer\GAL4ap-md544, show duplications of sensillum campaniformium, macrochaetae and microchaetae in their normal locations that are frequently tufted together. No effects are seen in the wing. Flies with Scer\UAS.cAa under the control of Scer\GAL4pnr-MD237, show multiplication of all chaetae between the two dorsocentral rows. Flies with Scer\UAS.cAa under the control of Scer\GAL432B or Scer\GAL4bi-md653 showed no wing pattern aberrations. Scer\UAS.cAa, when driven by Scer\GAL4ap-md544, creates clusters of wing margin sensory organ precursors (SOPs) in their normal locations in the dorsal row, where there would only be single SOPs in wild-type. The N/numb mediated asymmetric divisions in the SOP lineage are not affected. When Scer\UAS.cAa is driven by Scer\GAL4pnr-MD237 the duplications of the SOPs is accompanied by the equivalent duplication of their descendents, i.e the trichogen cell and tormogen cell, and the thecogen cell and its associated eo neuron, equal numbers of each being seen.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Enhanced by
NOT Enhanced by
Statement
Reference
NOT suppressed by
Statement
Reference
NOT Suppressor of
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference

Scer\UAS.cAa driven by Scer\GAL4455.2 cannot restore scutellar bristles to E(spl)Scer\UAS.cLa, HLHmδScer\UAS.cdCa or HLHmγScer\UAS.cLa. The presence of N264-40 enhances the supernumerary scutellar bristle phenotype seen in flies with Scer\UAS.cAa driven by Scer\GAL4455.2. The presence of NAx-1 or Dp(1;2)N+ reduces the number of supernumerary scutellar bristles seen in flies with Scer\UAS.cAa driven by Scer\GAL4455.2, though the number seen is still significantly higher than wild-type. The presence of Df(3R)grob32.2 enhances the supernumerary scutellar bristle phenotype seen in flies with Scer\UAS.cAa driven by Scer\GAL4455.2.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (1)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (4)
Reported As
Symbol Synonym
E(spl)mα-BFMScer\UAS.cAa
E(spl)mα-BFMUAS.cAa
Scer\UAS.cAa
Name Synonyms
Saccharomyces cerevisiae UAS construct a of Apidianakis
Secondary FlyBase IDs
    References (7)