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General Information
Symbol
Dmel\chifETBE3
Species
D. melanogaster
Name
FlyBase ID
FBal0101473
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Mutagen
    Nature of the Allele
    Mutagen
    Mutations Mapped to the Genome
     
    Type
    Location
    Additional Notes
    References
    Associated Sequence Data
    DNA sequence
    Protein sequence
     
     
    Cytology
    Nature of the lesion
    Statement
    Reference

    Deletion of approximately 6kb extending distally from the P{lacW}chifk08106h insertion, removing most of the open reading frame. Part of the P{lacW} element (position 9271 to 10698, numbering according to FBmc0000231) is still present.

    Expression Data
    Reporter Expression
    Additional Information
    Statement
    Reference
     
    Marker for
    Reflects expression of
    Reporter construct used in assay
    Human Disease Associations
    Disease Ontology (DO) Annotations
    Models Based on Experimental Evidence ( 0 )
    Disease
    Evidence
    References
    Modifiers Based on Experimental Evidence ( 0 )
    Disease
    Interaction
    References
    Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
     
    Disease-implicated variant(s)
     
    Phenotypic Data
    Phenotypic Class
    Phenotype Manifest In
    Detailed Description
    Statement
    Reference

    chifETBE3 follicle cell clones either fail to show the expected gene amplification (BrdU-positive foci) normally observed in controls or present picnotic nuclei.

    BrdU incorporation is not observed in homozygous chifETBE3 egg chamber clones in amplification stage follicle cells, whereas endocycle stage DNA replication continues, albeit with some differences in timing compared to surrounding wild type cells.

    External Data
    Interactions
    Show genetic interaction network for Enhancers & Suppressors
    Phenotypic Class
    Phenotype Manifest In
    Additional Comments
    Genetic Interactions
    Statement
    Reference
    Xenogenetic Interactions
    Statement
    Reference
    Complementation and Rescue Data
    Fails to complement
    Comments
    Images (0)
    Mutant
    Wild-type
    Stocks (0)
    Notes on Origin
    Discoverer
    External Crossreferences and Linkouts ( 0 )
    Synonyms and Secondary IDs (2)
    Reported As
    Name Synonyms
    Secondary FlyBase IDs
      References (3)