FB2025_01 , released February 20, 2025
Allele: Dmel\RelE23
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General Information
Symbol
Dmel\RelE23
Species
D. melanogaster
Name
FlyBase ID
FBal0101570
Feature type
allele
Associated gene
Dmel\Rel
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
Delta2-3 transposase
(Hedengren et al., 1999)
Progenitor genotype
RelL3141a
(Hedengren, 1999.9.14, Hedengren et al., 1999)
Cytology
Description

Precise excision of the P{lacW} element.

(Hedengren et al., 1999)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      RelE23 flies generally survive injection with E.cloacae β12 (injection with approximately 2 x 105 bacteria per fly), as do wild-type flies. Larvae show an efficient encapsulation reaction when infested with the parasitoid wasp L.boulardi. Total hemocyte cell number and morphology appears normal and the lymph glands are also not visibly affected.

      (Hedengren et al., 1999)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      NOT Suppressor of
      Phenotype Manifest In
      Other
      Statement
      Reference

      Df(2L)J4, RelE23 has salivary gland phenotype

      (Lehmann et al., 2002)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      The enhanced pathogen resistance phenotype of flies expressing PGRP-LEScer\UAS.T:Zzzz\FLAG driven by Scer\GAL4S106-GS is not suppressed by RelE23.

      (Libert et al., 2006)

      18% of RelE23/Df(2L)J4 mutant pupae have intact salivary glands at 16 hours after puparium formation. 18% of animals have no salivary glands, and 64% have degrading salivary glands.

      (Lehmann et al., 2002)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 1 )
      Crossreferences
      GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      E23
      (Lehmann et al., 2002)
      Rel23
      (Libert et al., 2006)
      RelE23
      Name Synonyms
      Secondary FlyBase IDs
        References (4)