E177K | Khc-PA
Reported base location of mutation is relative to noncoding strand.
Amino acid replacement: E177K.
Nucleotide substitution: G849A.
Revision of data reported in FBrf0111813.
lethal | recessive
lethal - all die before end of larval stage (with Df(2R)Jp6)
some die during third instar larval stage (with Df(2R)Jp6)
Khc19/Khc27 larvae show reduced flux of both neurosecretory dense core vesicles and mitochondria along the axons compared to wild type.
Hemizygotes do not survive to adulthood.