Allele Dmel\Hsrω^neo55

General Information
Symbol	Dmel\Hsrω^neo55	Species	D. melanogaster
Name		FlyBase ID	FBal0101635
Feature type	allele	Associated gene	Dmel\Hsrω

Map ( GBrowse )	Untitled Document
Allele class
Mutagen	P-element activity
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Nature of the Allele
Allele class
Mutagen	P-element activity (Cooley et al., 1988)
Mutations Mapped to the Genome

Type Location Additional Notes References transposable element insertion site 3R:17,122,223..17,122,223 (Cooley et al., 1988, Fernandez-Funez et al., 2000)
Associated Sequence Data
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name

UniProtKB/Swiss-Prot
UniProtKB/TrEMBL

Progenitor genotype
Nature of the lesion	Statement Reference The P{hsneo} insertion is 240bp upstream of the putative ATG start codon. (Fernandez-Funez et al., 2000)
Caused by insertion	P{hsneo}Hsrω^neo55 (Cooley et al., 1988, Fernandez-Funez et al., 2000)
Cytology
Phenotypic Data
Phenotypic Class

Phenotype Manifest In

Detailed Description
	Statement Reference Expression of Hsrω^neo55 under the control of Scer\GAL4^GMR.PF does not result in a rough eye phenotype. (Shulman and Feany, 2003)
External Data
Linkouts
Interactions
	Show the genetic interaction network for Enhancers & Suppressors
Phenotypic Class
NOT Enhancer of
Statement Reference Hsrω^neo55 is a non-enhancer of visible phenotype of Hsap\MAPT^{V337M.Scer\UAS}, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF (Shulman and Feany, 2003)
NOT Suppressor of
Statement Reference Hsrω^neo55 is a non-suppressor of visible phenotype of Hsap\MAPT^{V337M.Scer\UAS}, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF (Shulman and Feany, 2003)
Phenotype Manifest In
Enhancer of
Statement Reference Hsrω^neo55 is an enhancer of eye phenotype of Hsap\ATXN1^82Q.Scer\UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF (Fernandez-Funez et al., 2000) Hsrω^neo55 is an enhancer of retina phenotype of Hsap\ATXN1^82Q.Scer\UAS, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF (Fernandez-Funez et al., 2000)
NOT Enhancer of
Statement Reference Hsrω^neo55 is a non-enhancer of eye phenotype of Hsap\MAPT^{V337M.Scer\UAS}, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF (Shulman and Feany, 2003)
NOT Suppressor of
Statement Reference Hsrω^neo55 is a non-suppressor of eye phenotype of Hsap\MAPT^{V337M.Scer\UAS}, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF (Shulman and Feany, 2003)
Additional Comments
Genetic Interactions
Statement Reference
Xenogenetic Interactions
Statement Reference The rough eye phenotype caused by expression of Hsap\MAPT^{V337M.Scer\UAS} under the control of Scer\GAL4^GMR.PF is not modified if the flies are also carrying Hsrω^neo55. (Shulman and Feany, 2003)
Complementation & Rescue Data
Comments
Stocks ( 0 )

Notes on Origin
Discoverer
	The lethality of the "l(3)neo55" chromosome is separable from the P{hsneo}Hsrω^neo55 insertion. Separable from: l(3)neo55¹. (Cooley et al., 1988)
External Crossreferences & Linkouts
Other Crossreferences

Linkouts

Synonyms & Secondary IDs ( 3 )
Reported As
Symbol Synonym	Hsrω^neo55 l(3)neo55 (Shulman and Feany, 2003) v(3)neo55 (Beaton, 1999.12.12)
Name Synonym
Secondary FlyBase IDs

References ( 5 )
Research paper	Shulman and Feany, 2003, Genetics 165(3): 1233--1242 Genetic modifiers of tauopathy in Drosophila. [FBrf0167629] Fernandez-Funez et al., 2000, Nature 408(6808): 101--106 Identification of genes that modify ataxin-1-induced neurodegeneration. [FBrf0131287] Cooley et al., 1988, Science 239: 1121--1128 Insertional mutagenesis of the Drosophila genome with single P-elements. [FBrf0049003]
Personal communication to FlyBase	Beaton, 1999.12.12, Alleles of the lines in the P-element paper. Alleles of the lines in the P-element paper. [FBrf0125032] BDGP Project Members, 1994-1999, BDGP Project Members, 1994-1999, Berkeley Drosophila Genome Project. (Computer file) BDGP Project Members, 1994-1999, Berkeley Drosophila Genome Project. (Computer file) [FBrf0067338]

Allele Dmel\Hsrωneo55

Allele Dmel\Hsrω^neo55