FB2025_01 , released February 20, 2025
Allele: Dmel\GstS106253
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General Information
Symbol
Dmel\GstS106253
Species
D. melanogaster
Name
FlyBase ID
FBal0101656
Feature type
allele
Associated gene
Dmel\GstS1
Associated Insertion(s)
P{PZ}GstS106253
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
P-element activity
(Fernandez-Funez et al., 2000, Spradling, 1999.12.9, Spradling et al., 1999)
Progenitor genotype
Associated Insertion(s)
P{PZ}GstS106253
Cytology
Description
Allele components
Component
Use(s)
Inserted element
P{PZ}
Encoded product / tool
lacZ
Tagged with
Tag:NLS(P)
Mutations Mapped to the Genome
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 1 )
      Disease
      Interaction
      References
      exacerbates  olivopontocerebellar atrophy
      modeled by Hsap\ATXN182Q.UAS
      (Branco et al., 2008)
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      No obvious phenotype.

      (Spradling et al., 1999)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Enhancer of
      NOT Enhancer of
      Statement
      Reference

      GstS1[+]/GstS106253 is a non-enhancer of retina phenotype of Hsap\HTT128Q.1-336.UAS, Scer\GAL4GMR.PU

      (Branco et al., 2008)
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference

      One copy of GstS106253 does not enhance the retinal phenotype seen when Hsap\HTT128Q.1-336.Scer\UAS is expressed under the control of Scer\GAL4GMR.PU.

      One copy of GstS106253 enhances the retinal phenotype seen when Hsap\ATXN182Q.Scer\UAS is expressed under the control of Scer\GAL4GMR.PU.

      (Branco et al., 2008)
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer

      Separable from: l(2)0625306253. The lethality of the "l(2)06253" chromosome (caused by l(2)0625306253) is separable from the P{PZ}GstS106253 insertion.

      (Spradling, 1999.12.9)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      Gst206253
      (Fernandez-Funez et al., 2000)
      GstS106253
      n(2)06253
      (Spradling, 1999.12.9, Spradling et al., 1999)
      Name Synonyms
      Secondary FlyBase IDs
        References (4)