trichome & abdominal tergite (with stanE59)
The hexagonal packing of intervein cells, which usually occurs between wing development stage P2B (when the first morphological signs of veins appear (FBrf0005070), and the middle of P2C (before hair formation (FBrf0005070)) is partially disrupted in stan3/stan3 flies.
Relatively strong polarity phenotype in the adult cuticle. Wing hairs show a stereotypical abnormal polarity pattern of the fz/in class. Homozygotes show relatively few multiple hair cells, similar to fz, dsh and pk mutants. During morphogenesis in pupal wings stan prehairs form at a relatively central location on the apical cells surface, as opposed to at the distal-most vertex as is characteristic of wild type cells. Somatic clones in the wing show cell autonomous wing hair polarity defects.
stan3/stan3 is a suppressor of abnormal planar polarity | somatic clone | cell non-autonomous phenotype of fz15
stan3/stan3 is a suppressor of abnormal planar polarity | somatic clone phenotype of fz15
stanE59/stan3 is a suppressor of abnormal planar polarity phenotype of Scer\GAL4ptc-559.1, fzUAS.cSa
dsunspecified, stan3 has abnormal planar polarity phenotype
dsunspecified, stan3 has trichome & abdominal tergite phenotype
dsunspecified, stan3 has chaeta & abdominal tergite phenotype
The reversal of cell polarity that is seen in cells posterior to clones in the anterior compartment of the dorsal epidermis of the adult abdomen (in the tergite) where the clones are expressing dsecto.Scer\UAS under the control of Scer\GAL4αTub84B.PL is still seen if the clones are induced in a stan- background (the cells within the clone are stanE59/stanE59 while the cells surrounding the clone are stan3/stanE59).
Clones of cells in the anterior compartment of the dorsal epidermis of the adult abdomen (in the tergite) that are expressing fzScer\UAS.cUa under the control of Scer\GAL4αTub84B.PL in a stan- background (the cells within the clone are stanE59/stanE59 while the cells surrounding the clone are stan3/stanE59) do not change the cell polarity of the stan3/stanE59 cells surrounding the clone.
Clones of cells in the anterior compartment of the dorsal epidermis of the adult abdomen (in the tergite) that are co-expressing stanScer\UAS.cUa and fzScer\UAS.cUa under the control of Scer\GAL4αTub84B.PL in a stan- background (the cells within the clone are stanE59/stanE59 while the cells surrounding the clone are stan3/stanE59) do not change the cell polarity of the stan3/stanE59 cells surrounding the clone.
The reversal of cell polarity that is seen in cells anterior to clones in the anterior compartment of the dorsal epidermis of the adult abdomen (in the tergite) where the clones are expressing ftScer\UAS.cMa under the control of Scer\GAL4αTub84B.PL is still seen if the clones are induced in a stan- background (the cells within the clone are stanE59/stanE59 while the cells surrounding the clone are stan3/stanE59).
Clones of cells in the anterior compartment of the dorsal epidermis of the adult abdomen (in the tergite) that are expressing fjScer\UAS.cZa under the control of Scer\GAL4αTub84B.PL in a stan- background (the cells within the clone are stanE59/stanE59 while the cells surrounding the clone are stan3/stanE59) result in a reversal of cell polarity in cells anterior to the clone (hairs in front of the clone point forwards), as occurs in clones induced in a wild-type background.
The reversal of cell polarity that is seen in cells posterior to clones in the anterior compartment of the dorsal epidermis of the adult abdomen (in the tergite) where the clones are expressing dsecto.Scer\UAS under the control of Scer\GAL4αTub84B.PL is still seen if the clones are induced in a fzunspecified stan- background (cells within the clone are stanE59/stanE59 while the cells surrounding the clone are stan3/stanE59).
The reversal of cell polarity that is seen in cells anterior to clones in the anterior compartment of the dorsal epidermis of the adult abdomen (in the tergite) where the clones are expressing ftScer\UAS.cMa under the control of Scer\GAL4αTub84B.PL is still seen if the clones are induced in a fzunspecified stan- background (cells within the clone are stanE59/stanE59 while the cells surrounding the clone are stan3/stanE59).
Hair and bristle polarity is randomised throughout the tergite in dsunspecified stan3/stanE59 double mutant flies.
The reversal of cell polarity phenotype that is seen in cells posterior to clones in the anterior compartment of the dorsal epidermis of the adult abdomen (in the tergite) where the clones are doubly mutant for ptc16 and Df(2R)enE is still seen if the clones are induced in a stan3/stanE59 background, as occurs in clones induced a wild-type background.
The reversal of cell polarity phenotype that is seen in cells posterior to clones in the anterior compartment of the dorsal epidermis of the adult abdomen (in the tergite) where the clones are doubly mutant for ptc16 and Df(2R)enE is not seen if the clones are induced in a dsunspecified stan3/stanE59 double mutant background instead of a wild-type background.
A stan3/stan3 background blocks planar repolarisation both inside and outside fz15 homozygous clones in the abdomen.
stanE59/stan3 suppresses the planar repolarisation in the adult abdomen caused by fzScer\UAS.cSa; Scer\GAL4ptc-559.1.
The domineering non-autonomy of the fz23 clone phenotype is largely, but not completely, suppressed by stan3. stan3 completely blocks the ability of a gradient of fz expression to reorganize wing hair polarity. stan3 does not block the ability of fzhs.PP to form multiple hairs, it rather enhances the fzhs.PP multiple hair phenotype slightly.
Strong hypomorph.