Allele Dmel\nos^{627.αTub84B.UTR.T:Ivir\HA1}

General Information
Symbol	Dmel\nos^{627.αTub84B.UTR.T:Ivir\HA1}	Species	D. melanogaster
Name		FlyBase ID	FBal0102446
Feature type	allele	Associated gene	Dmel\nos

Allele class
Mutagen	ethyl methanesulfonate
Recent Updates
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FB2013_03
FB2013_02
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Nature of the Allele
Allele class
Mutagen	ethyl methanesulfonate (Arrizabalaga and Lehmann, 1999)
Mutations Mapped to the Genome

Type Location Additional Notes References
Associated Sequence Data
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name

UniProtKB/Swiss-Prot
UniProtKB/TrEMBL

Progenitor genotype	nos^{αTub84B.UTR.T:Ivir\HA1} (Arrizabalaga and Lehmann, 1999)
Nature of the lesion	Statement Reference Nucleotide substitution: G1934A. Amino acid replacement: R351Q. The number of the base mutated corresponds to the numbering given for the genomic sequence of nos in FBrf0053387, with one correction: an extra three bases (AGA) have been found between bases 1410 and 1411, replacing His 201 with Gln and Ile. (Arrizabalaga and Lehmann, 1999)
Carried in construct	P{nos^{627.αTub84B.UTR.T:Ivir\HA1}} (Arrizabalaga and Lehmann, 1999)
Tagged with	T:Ivir\HA1 (Arrizabalaga and Lehmann, 1999) T:Zzzz\FLAG (Mutsuddi et al., 2005)
Cytology
Phenotypic Data
Phenotypic Class
	female fertile (Arrizabalaga and Lehmann, 1999)
Phenotype Manifest In

Detailed Description
	Statement Reference
External Data
Linkouts
Interactions
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement Reference
Xenogenetic Interactions
Statement Reference
Complementation & Rescue Data
Fails to rescue	nos^{627.αTub84B.UTR.T:Ivir\HA1} fails to rescue nos¹⁸ (Arrizabalaga and Lehmann, 1999) nos^{627.αTub84B.UTR.T:Ivir\HA1} fails to rescue nos¹⁸/Df(3R)Dl-X43 (Arrizabalaga and Lehmann, 1999)
Comments	Fails to rescue the abdominal phenotype of embryos derived from nos¹⁸ females. Fails to rescue the oogenesis defects of embryos derived from nos¹⁸/Df(3R)Dl-X43 females. (Arrizabalaga and Lehmann, 1999)
Stocks ( 0 )

Notes on Origin
Discoverer
	Selected as: a mutation that reverts the female sterile phenotype of flies carrying nos^{αTub84B.UTR.T:Ivir\HA1}. (Arrizabalaga and Lehmann, 1999)
External Crossreferences & Linkouts
Other Crossreferences

Linkouts

Synonyms & Secondary IDs ( 2 )
Reported As
Symbol Synonym	nos^{627.αTub84B.UTR.T:Ivir\HA1} nos⁶²⁷ (Arrizabalaga and Lehmann, 1999)
Name Synonym
Secondary FlyBase IDs

References ( 2 )
Research paper	Mutsuddi et al., 2005, Genetics 170(2): 687--695 Using Drosophila to decipher how mutations associated with human branchio-oto-renal syndrome and optical defects compromise the protein tyrosine phosphatase and transcriptional functions of eyes absent. [FBrf0188574] Arrizabalaga and Lehmann, 1999, Genetics 153(4): 1825--1838 A selective screen reveals discrete functional domains in Drosophila nanos. [FBrf0122951]

Allele Dmel\nos627.αTub84B.UTR.T:Ivir\HA1

Allele Dmel\nos^{627.αTub84B.UTR.T:Ivir\HA1}