Allele Dmel\iab-4¹⁶⁶

General Information
Symbol	Dmel\iab-4¹⁶⁶	Species	D. melanogaster
Name		FlyBase ID	FBal0102679
Feature type	allele	Associated gene	Dmel\iab-4

Allele class
Mutagen	X ray
Recent Updates
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FB2013_03
FB2013_02
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Nature of the Allele
Allele class
Mutagen	X ray (Karch et al., 1985)
Mutations Mapped to the Genome

Type Location Additional Notes References
Associated Sequence Data
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name

UniProtKB/Swiss-Prot
UniProtKB/TrEMBL

Progenitor genotype	Abd-B^Mcp-1
Nature of the lesion	Statement Reference Break lies in the iab-4 transcription unit. (Cumberledge et al., 1990) Lesion mapped to: 76-83 kb. (Karch et al., 1985)
Caused by aberration	In(3LR)iab4¹⁶⁶ (Cumberledge et al., 1990, Karch et al., 1985, )
Cytology
Phenotypic Data
Phenotypic Class
	viable (Jijakli and Ghysen, 1992)
Phenotype Manifest In
	gonad \| precursor (Boyle and DiNardo, 1995, Warrior, 1994) pole cell (Boyle and DiNardo, 1995)
Detailed Description
	Statement Reference Gonadal precursors do not coalesce into a gonad. Pole cells are released from the stalled gonadal precursors and are scattered throughout the embryo. (Boyle and DiNardo, 1995) Defective in gonad assembly. (Warrior, 1994)
External Data
Linkouts
Interactions
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement Reference
Xenogenetic Interactions
Statement Reference
Complementation & Rescue Data
Comments
Stocks ( 0 )

Notes on Origin
Discoverer	von der Ahe. J. Von Der Ahe.
	Induced with: abd-A^iab4-166. (Cumberledge et al., 1990)
Comments
	Mutations in iab-4 have effects on the abd-A transcription unit, so such mutations are considered to be simultaneously mutant for iab-4 and abd-A.
External Crossreferences & Linkouts
Other Crossreferences

Linkouts

Synonyms & Secondary IDs ( 4 )
Reported As
Symbol Synonym	iab4¹⁶⁶ (Eberhart and Wasserman, 1995, ) iab-4¹⁶⁶ iab4^31166.1 Mcp^rev31166.1
Name Synonym
Secondary FlyBase IDs

References ( 6 )
Research paper	Boyle and DiNardo, 1995, Development 121(6): 1815--1825 Specification, migration and assembly of the somatic cells of the Drosophila gonad. [FBrf0078101] Eberhart and Wasserman, 1995, Development 121(10): 3477--3486 The pelota locus encodes a protein required for meiotic cell division: An analysis of G2/M arrest in Drosophila spermatogenesis. [FBrf0083884] Warrior, 1994, Dev. Biol. 166(1): 180--194 Primordial germ cell migration and the assembly of the Drosophila embryonic gonad. [FBrf0076121] Jijakli and Ghysen, 1992, Int. J. Dev. Biol. 36(1): 93--99 Segmental determination in Drosophila central nervous system: analysis of the abdominal-A region of the Bithorax complex. [FBrf0056377] Cumberledge et al., 1990, Proc. Natl. Acad. Sci. U.S.A. 87: 3259--3263 Characterization of two RNAs transcribed from the cis-regulatory region of the abd-A domain within the Drosophila bithorax complex. [FBrf0052838] Karch et al., 1985, Cell 43: 81--96 The abdominal region of the Bithorax complex. [FBrf0042053]

Allele Dmel\iab-4166

Allele Dmel\iab-4¹⁶⁶