Allele Dmel\Su(H)^Scer\UAS.cGa

General Information
Symbol	Dmel\Su(H)^Scer\UAS.cGa	Species	D. melanogaster
Name	Saccharomyces cerevisiae UAS construct a of Go	FlyBase ID	FBal0102830
Feature type	allele	Associated gene	Dmel\Su(H)

Allele class
Mutagen	in vitro construct - regulatory fusion
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Nature of the Allele
Allele class
Mutagen	in vitro construct - regulatory fusion (Helms et al., 1999)
Mutations Mapped to the Genome

Type Location Additional Notes References
Associated Sequence Data
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name

UniProtKB/Swiss-Prot
UniProtKB/TrEMBL

Progenitor genotype
Nature of the lesion	Statement Reference
Carried in construct	P{UAS-Su(H).G} (Han and Bodmer, 2003, Yedvobnick et al., 2001, Kumar and Moses, 2001, Kumar and Moses, 2001, Helms et al., 1999, Koelzer and Klein, 2006, Kim et al., 2010)
Cytology
Phenotypic Data
Phenotypic Class

Phenotype Manifest In

Detailed Description
	Statement Reference When Su(H)^Scer\UAS.cGa is driven by Scer\GAL4^eve.eme no effect is seen on normal cardiac/muscle fate determination. (Han and Bodmer, 2003) Expression of Su(H)^Scer\UAS.cGa under the control of Scer\GAL4^ey.PB has no effect on either eye or antenna disc development. (Kumar and Moses, 2001)
External Data
Linkouts
Interactions
	Show the genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Suppressed by
Statement Reference Scer\GAL4^bbg-C96, Su(H)^Scer\UAS.cGa has wing sensillum phenotype, suppressible by mam^N.Scer\UAS/Scer\GAL4^bbg-C96 (Helms et al., 1999)
NOT Enhancer of
Statement Reference Su(H)^Scer\UAS.cGa/Scer\GAL4^bbg-C96 is a non-enhancer of wing phenotype of Scer\GAL4^bbg-C96, mam^N.Scer\UAS (Helms et al., 1999)
NOT Suppressor of
Statement Reference Su(H)^Scer\UAS.cGa/Scer\GAL4^bbg-C96 is a non-suppressor of wing phenotype of Scer\GAL4^bbg-C96, mam^N.Scer\UAS (Helms et al., 1999)
Additional Comments
Genetic Interactions
Statement Reference Has no effect on the wing nicking phenotype seen in mam^N.Scer\UAS, Scer\GAL4^C96 flies. The wing bristle phenotype seen in Su(H)^Scer\UAS.cGa, Scer\GAL4^C96 flies is mildly suppressed by the addition of mam^N.Scer\UAS. (Helms et al., 1999)
Xenogenetic Interactions
Statement Reference
Complementation & Rescue Data
Rescues	Su(H)^Scer\UAS.cGa/Scer\GAL4^tin.CΔ4 rescues Df(2L)Exel7007 (Kim et al., 2010)
Comments	Expression of Su(H)[Scer\UAS.cGa] under the control of Scer\GAL4[tin.CΔ4] rescues the abnormal cardiac function of Df(2L)Exel7007 flies. (Kim et al., 2010)
Stocks ( 0 )

Notes on Origin
Discoverer

External Crossreferences & Linkouts
Other Crossreferences

Linkouts

Synonyms & Secondary IDs ( 2 )
Reported As
Symbol Synonym	Su(H)^Scer\UAS.cGa
Name Synonym	Saccharomyces cerevisiae UAS construct a of Go (Helms et al., 1999)
Secondary FlyBase IDs

References ( 7 )
Research paper	Kim et al., 2010, Circulation Res. 106(7): 1233--1243 Gene deletion screen for cardiomyopathy in adult Drosophila identifies a new notch ligand. [FBrf0210603] Koelzer and Klein, 2006, Dev. Biol. 289(1): 77--90 Regulation of expression of Vg and establishment of the dorsoventral compartment boundary in the wing imaginal disc by Suppressor of Hairless. [FBrf0190133] Han and Bodmer, 2003, Development 130(13): 3039--3051 Myogenic cells fates are antagonized by Notch only in asymmetric lineages of the Drosophila heart, with or without cell division. [FBrf0160590] Kumar and Moses, 2001, Cell 104(5): 687--697 EGF receptor and Notch signaling act upstream of Eyeless/Pax6 to control eye specification. [FBrf0134490] Kumar and Moses, 2001, Development 128(14): 2689--2697 The EGF receptor and notch signaling pathways control the initiation of the morphogenetic furrow during Drosophila eye development. [FBrf0138358] Yedvobnick et al., 2001, genesis 30(4): 250--258 Identification of chromosomal deficiencies that modify Drosophila mastermind mutant phenotypes. [FBrf0138541] Helms et al., 1999, Dev. Biol. 215(2): 358--374 Engineered truncations in the Drosophila mastermind protein disrupt Notch pathway function. [FBrf0111904]

Allele Dmel\Su(H)Scer\UAS.cGa

Allele Dmel\Su(H)^Scer\UAS.cGa