A Database of Drosophila Genes & Genomes

FB2013_03, released May 7th, 2013
 

Allele Dmel\Klp64DScer\UAS.cRa

General Information
SymbolDmel\Klp64DScer\UAS.cRaSpeciesD. melanogaster
NameSaccharomyces cerevisiae UAS construct a of RayFlyBase IDFBal0102966
Feature typealleleAssociated geneDmel\Klp64D
Allele class
Mutagenin vitro construct - regulatory fusion
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Description
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FB2013_03
FB2013_02
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Allele class
Mutagen
Mutations Mapped to the Genome
Type
Location
Additional Notes
References
Associated Sequence Data
DDBJ /
EMBL /
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DNA sequence
Protein sequence
Name
 
UniProtKB/Swiss-Prot
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Progenitor genotype
Nature of the lesion
Statement
Reference
Construct: An approximately 3.6kb genomic fragment containing the full length Klp64D coding sequence, 447bp of 5' upstream sequences including the TATA box and about 0.8kb of 3' sequences is fused downstream of Scer\UAS regulatory sequences.
Carried in construct
Cytology
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Rescues
Comments
Expression of Klp64D[Scer\UAS.cRa] under the control of Scer\GAL4[da.G32] rescues the reduced electroantennogram response of Klp64D[k5]/Klp64D[k1] adults in response to ethyl acetate, n-butanol, benzaldehyde or propionic acid.
Rescues the lethality and uncoordinated behaviour of Klp64Dk1 and Klp64Dk5, either in homozygous condition or in transheterozygous combination with Klp64Dn123, in the absence of a Scer\GAL4 driver.
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Bloomington
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Reported As
Symbol Synonym
Klp64DScer\UAS.cRa
 
Name Synonym
Saccharomyces cerevisiae UAS construct a of Ray
Secondary FlyBase IDs
hide References ( 4 )
Research paper
Jana et al., 2011, Mol. Biol. Cell 22(6): 769--781
Heterotrimeric kinesin-II is necessary and sufficient to promote different stepwise assembly of morphologically distinct bipartite cilia in Drosophila antenna. [FBrf0213262]
Baqri et al., 2006, J. Neurobiol. 66(4): 378--392
Kinesin-2 differentially regulates the anterograde axonal transports of acetylcholinesterase and choline acetyltransferase in Drosophila. [FBrf0191019]
Sarpal et al., 2003, Curr. Biol. 13(19): 1687--1696
Drosophila KAP interacts with the kinesin II motor subunit KLP64D to assemble chordotonal sensory cilia, but not sperm tails. [FBrf0167402]
Ray et al., 1999, J. Cell Biol. 147(3): 507--518
Kinesin-II is required for axonal transport of choline acetyltransferase in Drosophila. [FBrf0112015]