Border cells migrate normally when grkΔTC.Scer\UAS is expressed under the control of Scer\GAL4cb41 in follicle cell clones.
Expression of one copy of grkΔTC.Scer\UAS in the border cell cluster, driven by Scer\GAL4slbo.2.6, causes a defects in border cell migration in egg chambers with around a 30% penetrance. Increasing the number of copies of the grkΔTC.Scer\UAS transgene increases the penetrance and severity of the phenotype.
100% of border cell clusters migrate normally to the oocyte in egg chambers expressing grkΔTC.Scer\UAS under the control of Scer\GAL4Act5C.PI in anterior follicle cell clones.
When expressed in ovarian follicle cells under the control of Scer\GAL4CY2, eggs laid become dorsalised. When expressed in the wing disc under the control of Scer\GAL4CY2, extra wing veins are produced. When expressed under the control of Scer\GAL4en-e16E, very few flies survive, however in escapers, an expansion of wing vein 4 up to the compartment boundary is seen in both wings, though this expansion does not extend over the boundary.