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General Information
Symbol
Dmel\fngEP3082
Species
D. melanogaster
Name
FlyBase ID
FBal0103826
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
EP(3)3082, EP-fringe
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference
Insertion components
P{EP}fngEP3082
Product class / Tool use(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Expression of fngEP3082 under the control of Scer\GAL4ey.PH results in a small eye.

Expression of fngEP3082 under the control of Scer\GAL4ey.PH results in eyes that are strongly reduced in size. Flies expressing fngEP3082 under the control of Scer\GAL4hs.2sev have wild-type eyes. Flies expressing fngEP3082 under the control of Scer\GAL4en-e16E have reduced wings.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Suppressed by
Statement
Reference
Suppressor of
Other
Phenotype Manifest In
Suppressed by
Statement
Reference
Suppressor of
NOT Suppressor of
Other
Additional Comments
Genetic Interactions
Statement
Reference

Co-expression of CycEScer\UAS.cLa suppresses the small eye phenotype caused by expression of fngEP3082 under the control of Scer\GAL4ey.PH.

Expression of fngEP3082 under the control of Scer\GAL4ap-md544 does not restore a smooth boundary between the dorsal and ventral cells in apmd544/apUGO35 wing discs.

Growth of the wing and wing margin formation can be restored in apmd544/apUGO35 flies expressing fngEP3082 under the control of Scer\GAL4ap-md544. Both surfaces of the wing differentiate ventral structures; the anterior wing margin and alula differentiate ventral bristles on both surfaces and the pattern of vein corrugation is ventral. Co-expression of fngEP3082 and DrScer\UAS.cIa under the control of Scer\GAL4ap-md544 in apmd544/apUGO35 flies results in dorsal differentiation in bristles of the dorsal anterior wing margin.

aprK568/apmd544 flies expressing fngEP3082 under the control of Scer\GAL4ap-md544 have wing margin defects.

The severity of the BxhdpR590/Y wing phenotype is partially suppressed by expression of fngEP3082 under the control of Scer\GAL4Bx-hdpR590.

Expression of fngEP3082 under the control of Scer\GAL4ap-md544 rescues the phenotype of apmd544/apUGO35 flies. Patches of ectopic wing margin form and can be associated with outgrowth of the wing. Cells appear to violate the dorsoventral boundary in apmd544/apUGO35 wing discs which are also expressing fngEP3082 under the control of Scer\GAL4ap-md544. Expression of both SerScer\UAS.cSa and fngEP3082 under the control of Scer\GAL4ap-md544 in apmd544/apUGO35 flies results in well-developed wings which differentiate ventral features on both surfaces; the wing margin, veins and sense organs on the topologically dorsal surface have exclusively ventral identity.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Name Synonyms
Secondary FlyBase IDs
    References (9)