|Name||Saccharomyces cerevisiae UAS construct a of Schock||FlyBase ID||FBal0103887|
|Feature type||allele||Associated gene||Dmel\btd|
|Mutagen||in vitro construct - regulatory fusion|
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|Nature of the Allele|
|Mutations Mapped to the Genome|
|Associated Sequence Data|
|Nature of the lesion|
|Carried in construct|
|Phenotype Manifest In|
Clones expressing btd[Scer\UAS.cSa], generated under the control of Scer\GAL4[tub.PU] using the MARCM system, show ectopic leg tissues in the wing. Both proximal and distal leg structures can be seen.
Expression of btdScer\UAS.cSa under the control of Scer\GAL4btd-MD808 causes the Keilin's organs to develop more than the the wild-type number of three sensory hairs.
When btdScer\UAS.cSa is driven by Scer\GAL4ey.PH, the original eye disappears and is replaced by an ectopic antenna, which often fuses with the normal one. When btdScer\UAS.cSa is driven by Scer\GAL4nub-AC-62, wings and halteres differentiate leg tissue. The leg tissue in these flies is not arranged in segments but it is possible to recognise pattern elements distal markers such as claws are found as well as tarsal and tibia-like bristles. The amount of leg tissue produced in each of these appendages is greater than the corresponding individual legs. When btdScer\UAS.cSa is driven by Scer\GAL4MD743 or Scer\GAL4bi-omb-Gal4 sets of leg structures are seen in the wing disc derivatives. btdScer\UAS.cSa clones (driven by Scer\GAL4Act5C.PP) in the haltere and wing differentiate leg tissue. These clones normally appear as either vesicles of tissue segregated from the wing and the haltere, or as protruding tissue. They tend to form leg patterns resembling normal ones, which include the formation of various leg segments. Moreover, these clones develop nearly complete leg patterns independently of the wing region where they localise.
|Phenotype Manifest In|
Scer\GAL4tub.PU, btdScer\UAS.cSa has leg | distal | ectopic | somatic clone phenotype, suppressible by Dll17
|NOT suppressed by|
A Dll mutant background partially suppresses the ectopic leg tissue phenotype seen when btd[Scer\UAS.cSa] clones are generated under the control of Scer\GAL4[tub.PU] using the MARCM system. These clones cannot generate distal leg fates, but are able to produce what appears to be proximal leg tissue.
|Complementation & Rescue Data|
|Fails to rescue|
Expression of btd[Scer\UAS.cSa] (using the MARCM system under the control of Scer\GAL4[tub.PU]) fails to rescue the growth defects seen in Df(1)btd-Sp1 leg disc clones generated in second instar larvae. Expression of btd[Scer\UAS.cSa] fails to rescue the growth defects seen in Df(1)btd-Sp1 mutant leg clones generated in a minute background during embryogenesis using Scer\FLP1[Scer\UAS.cUa] under the control of Scer\GAL4[Dll-em212].
|Stocks ( 1 )|
|Notes on Origin|
|External Crossreferences & Linkouts|
|Synonyms & Secondary IDs ( 2 )|
Saccharomyces cerevisiae UAS construct a of Schock
|Secondary FlyBase IDs|
|References ( 4 )|