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General Information
Symbol
Dmel\Sp1UAS.cSa
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct a of Schock
FlyBase ID
FBal0103959
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
UAS-Sp1
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference

UAS regulatory sequences drive expression of Sp1.

Allele components
Product class / Tool use(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

The expression of Sp1Scer\UAS.cSa under the control of Scer\GAL4ptc.PU, in combination with gal80[ts] to induce expression from third instar larval stage onwards, leads to defects in joint formation both in prepupal leg discs and in adults, as compared to controls; expression under the control of Scer\GAL4Dll-em212 results in the conversion of the antennal segment 3 and the arista into a leg-like structure.

Ectopic expression of Sp1Scer\UAS.cSa driven by Scer\GAL4sca-537.4 causes development of mechanosensory stout bristles in ectopic places in the wing, including the posterior margin, veins and intervein regions.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments

Expression of Sp1Scer\UAS.cSa (using the MARCM system under the control of Scer\GAL4tub.PU) fully rescues the growth defects seen in Df(1)btd-Sp1 leg disc clones generated in second instar larvae.

Expression of Sp1Scer\UAS.cSa significantly rescues the growth defects seen in Df(1)btd-Sp1 mutant leg clones generated in a minute background during embryogenesis using Scer\FLP1Scer\UAS.cUa under the control of Scer\GAL4Dll-em212.

Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (3)
Reported As
Symbol Synonym
Sp1Scer\UAS.cSa
Sp1UAS.cSa
Name Synonyms
Saccharomyces cerevisiae UAS construct a of Schock
Secondary FlyBase IDs
    References (4)