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General Information
Symbol
Hsap\RAF1Δ305.αTub84B.Tag:Myr(Src64B)
Species
H. sapiens
Name
FlyBase ID
FBal0104115
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Carried in construct
Cytology
Nature of the lesion
Statement
Reference

The FRT cassette has been excised, juxtaposing αTub84B promoter sequences with an activated form of Hsap\RAF1 (which contains a 305 amino acid N-terminal truncation), tagged with a myristoylation sequence (Tag:Myr(Src64B)).

Allele components
Product class / Tool use(s)
Regulatory region(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Clones of Hsap\RAF1Δ305.αTub84B.T:Myr1 in the adult abdomen do not show any consistent alterations of normal polarity.

Expression of Hsap\RAF1Δ305.αTub84B.T:Myr1 in the eye disc induces ectopic photoreceptor differentiation just anterior to the morphogenetic furrow.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (3)
Reported As
Symbol Synonym
Hsap\RAF1Δ305.αTub84B.T:Myr-Src64B
Hsap\RAF1Δ305.αTub84B.T:Myr1
Hsap\RAF1Δ305.αTub84B.Tag:Myr(Src64B)
Name Synonyms
Secondary FlyBase IDs
    References (3)