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General Information
Symbol
Dmel\nkdUAS.Tag:MYC
Species
D. melanogaster
Name
FlyBase ID
FBal0104472
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
UAS-nkd
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference

UAS regulatory sequences drive expression of nkd tagged with Tag:MYC.

Allele components
Product class / Tool use(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Expression of a weakly expressing line of nkdScer\UAS.T:Hsap\MYC under the control of Scer\GAL4B119 results in a teardrop-shaped ventral eye and causes loss and lateral displacement of sternite bristles in the ventral abdomen. Expression of a more strongly expressing line of nkdScer\UAS.T:Hsap\MYC under the control of Scer\GAL4B119 results in ventral eye reduction and almost complete loss of sternite bristles in the ventral abdomen.

In nkdScer\UAS.T:Hsap\MYC; Scer\GAL4ap-md544 wing discs the dorsal compartment is reduced in size compared to the ventral compartment. These flies survive to adulthood and have wings with a reduced dorsal surface, which curls upwards.

nkdScer\UAS.T:Hsap\MYC when driven by Scer\GAL4GMR.PF has no visible effect on eye development.

Expression of nkdScer\UAS.T:Hsap\MYC when driven by Scer\GAL4hs.PB 24 h after puparium formation (APF) produces adult flies with wing hair polarity defects that are indistinguishable from those seen in dsh1 mutant adults.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments

Expression of nkdScer\UAS.T:Hsap\MYC under the control of Scer\GAL4da.G32 rescues the cuticle defects of nkd2/nkd3 embryos.

Images (0)
Mutant
Wild-type
Stocks (1)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (3)
Reported As
Symbol Synonym
nkdScer\UAS.T:Hsap\MYC
nkdUAS.Tag:MYC
Name Synonyms
Secondary FlyBase IDs
    References (5)