Allele Dmel\dos^{ΔPH.hs.T:Avic\GFP}

General Information
Symbol	Dmel\dos^{ΔPH.hs.T:Avic\GFP}	Species	D. melanogaster
Name		FlyBase ID	FBal0104655
Feature type	allele	Associated gene	Dmel\dos

Allele class
Mutagen	in vitro construct - deletion
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Nature of the Allele
Allele class
Mutagen	in vitro construct - deletion (Bausenwein et al., 2000)
Mutations Mapped to the Genome

Type Location Additional Notes References
Associated Sequence Data
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name

UniProtKB/Swiss-Prot
UniProtKB/TrEMBL

Progenitor genotype	dos^{hs.T:Avic\GFP} (Bausenwein et al., 2000)
Nature of the lesion	Statement Reference Construct: The N terminal PH domain has been removed. (Bausenwein et al., 2000)
Carried in construct	P{hs-dos.ΔPH-GFP} (Bausenwein et al., 2000)
Tagged with	T:Avic\GFP (Bausenwein et al., 2000)
Cytology
Phenotypic Data
Phenotypic Class

Phenotype Manifest In
	eye (Bausenwein et al., 2000) wing vein (Bausenwein et al., 2000)
Detailed Description
	Statement Reference The addition of dos^{ΔPH.hs.T:Avic\GFP} to dos^R31 or dos^P115 homozygotes or dos^P115/dos^R31 flies leads to pharate lethality. Escapers show defects in eye morphology and in wing vein formation. (Bausenwein et al., 2000)
External Data
Linkouts
Interactions
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement Reference
Xenogenetic Interactions
Statement Reference
Complementation & Rescue Data
Fails to rescue	dos^{ΔPH.hs.T:Avic\GFP} fails to rescue dos^P115 (Bausenwein et al., 2000) dos^{ΔPH.hs.T:Avic\GFP} fails to rescue dos^R31 (Bausenwein et al., 2000)
Comments	The addition of dos^{ΔPH.hs.T:Avic\GFP} to dos^R31, sev^{S11.T:Hsap\MYC} flies fails to restore the multiple R7 phenotype suppressed in sev^{S11.T:Hsap\MYC} flies when dos^R31 is added. The addition of dos^{ΔPH.hs.T:Avic\GFP} to dos^R31 or dos^P115 homozygotes or dos^P115/dos^R31 flies fails to produce viable flies. (Bausenwein et al., 2000)
Stocks ( 0 )

Notes on Origin
Discoverer

External Crossreferences & Linkouts
Other Crossreferences

Linkouts

Synonyms & Secondary IDs ( 1 )
Reported As
Symbol Synonym	dos^{ΔPH.hs.T:Avic\GFP}
Name Synonym
Secondary FlyBase IDs

References ( 1 )
Research paper	Bausenwein et al., 2000, Mech. Dev. 90(2): 205--215 In vivo functional analysis of the daughter of sevenless protein in receptor tyrosine kinase signaling. [FBrf0126713]

Allele Dmel\dosΔPH.hs.T:Avic\GFP

Allele Dmel\dos^{ΔPH.hs.T:Avic\GFP}