Allele Dmel\dos::Hsap\GAB1^{hs.T:Avic\GFP}

General Information
Symbol	Dmel\dos::Hsap\GAB1^{hs.T:Avic\GFP}	Species	D. melanogaster
Name		FlyBase ID	FBal0104657
Feature type	allele	Associated gene	Dmel\dos::Hsap\GAB1

Allele class
Mutagen	in vitro construct - coding region fusion, in vitro construct - deletion
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Nature of the Allele
Allele class
Mutagen	in vitro construct - coding region fusion (Bausenwein et al., 2000) in vitro construct - deletion (Bausenwein et al., 2000)
Mutations Mapped to the Genome

Type Location Additional Notes References
Associated Sequence Data
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name

UniProtKB/Swiss-Prot
UniProtKB/TrEMBL

Progenitor genotype	dos^{hs.T:Avic\GFP} (Bausenwein et al., 2000)
Nature of the lesion	Statement Reference Construct: The dos PH domain has been replaced by the dos::Hsap\GAB1 PH domain. (Bausenwein et al., 2000)
Carried in construct	P{hs-PH.GAB1-dos-GFP} (Bausenwein et al., 2000)
Tagged with	T:Avic\GFP (Bausenwein et al., 2000)
Cytology
Phenotypic Data
Phenotypic Class

Phenotype Manifest In

Detailed Description
	Statement Reference
External Data
Linkouts
Interactions
	Show the genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Enhancer of
Statement Reference dos::Hsap\GAB1^{hs.T:Avic\GFP} is an enhancer of photoreceptor cell R7 phenotype of dos^R31, sev^{S11.T:Hsap\MYC} (Bausenwein et al., 2000)
Additional Comments
Genetic Interactions
Statement Reference The addition of dos::Hsap\GAB1^{hs.T:Avic\GFP} to dos^R31/sev^{S11.T:Hsap\MYC} flies restores the multiple R7 phenotype suppressed in sev^{S11.T:Hsap\MYC} flies when dos^R31 is added. The addition of dos::Hsap\GAB1^{hs.T:Avic\GFP} to dos^R31 or dos^P115 homozygotes or dos^P115/dos^R31 flies leads to the recovery of fully viable flies. (Bausenwein et al., 2000)
Xenogenetic Interactions
Statement Reference The addition of dos::Hsap\GAB1^{hs.T:Avic\GFP} to dos^R31/sev^{S11.T:Hsap\MYC} flies restores the multiple R7 phenotype suppressed in sev^{S11.T:Hsap\MYC} flies when dos^R31 is added. The addition of dos::Hsap\GAB1^{hs.T:Avic\GFP} to dos^R31 or dos^P115 homozygotes or dos^P115/dos^R31 flies leads to the recovery of fully viable flies. (Bausenwein et al., 2000)
Complementation & Rescue Data
Comments
Stocks ( 0 )

Notes on Origin
Discoverer

External Crossreferences & Linkouts
Other Crossreferences

Linkouts

Synonyms & Secondary IDs ( 1 )
Reported As
Symbol Synonym	dos::Hsap\GAB1^{hs.T:Avic\GFP}
Name Synonym
Secondary FlyBase IDs

References ( 1 )
Research paper	Bausenwein et al., 2000, Mech. Dev. 90(2): 205--215 In vivo functional analysis of the daughter of sevenless protein in receptor tyrosine kinase signaling. [FBrf0126713]

Allele Dmel\dos::Hsap\GAB1hs.T:Avic\GFP

Allele Dmel\dos::Hsap\GAB1^{hs.T:Avic\GFP}