Allele Scer\GAL4^loco.1.3

General Information
Symbol	Scer\GAL4^loco.1.3	Species	S. cerevisiae
Name		FlyBase ID	FBal0104719
Feature type	allele	Associated gene	Scer\GAL4

Allele class
Mutagen	in vitro construct - regulatory fusion
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Nature of the Allele
Allele class
Mutagen	in vitro construct - regulatory fusion (Granderath et al., 2000)
Mutations Mapped to the Genome

Type Location Additional Notes References
Associated Sequence Data
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name

UniProtKB/Swiss-Prot
UniProtKB/TrEMBL

Progenitor genotype
Nature of the lesion	Statement Reference Construct: Scer\GAL4 expression is driven by 1.9kb of genomic sequences starting just 5' to the loco c1 transcription start. (Granderath et al., 2000)
Carried in construct	P{GAL4-loco.1.3} (Tschaepe et al., 2002, Jhaveri et al., 2004, Kuppers-Munther et al., 2004, Granderath et al., 2000, Muhlig-Versen et al., 2005, Schmidt et al., 2011, Edenfeld et al., 2006)
Cytology
Phenotypic Data
Phenotypic Class
	cell migration defective, with tgo^DN.Scer\UAS (Schmidt et al., 2011) neuroanatomy defective, with sws^Scer\UAS.cMa (Muhlig-Versen et al., 2005) neuroanatomy defective, with tgo^DN.Scer\UAS (Schmidt et al., 2011)
Phenotype Manifest In
	antennal lobe glomerulus \| ectopic, with sli^Scer\UAS.cKa (Jhaveri et al., 2004) CNS glial cell, with sws^Scer\UAS.cMa (Muhlig-Versen et al., 2005) epithelial glial cell, with sws^Scer\UAS.cMa (Muhlig-Versen et al., 2005) exit glial cell, with tgo^DN.Scer\UAS (Schmidt et al., 2011) glial cell, with tgo^DN.Scer\UAS (Schmidt et al., 2011)
Detailed Description
	Statement Reference
External Data
Linkouts
Interactions
	Show the genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Suppressor of
Statement Reference Scer\GAL4^loco.1.3/Mmus\NTE^Scer\UAS.cMa is a suppressor of neuroanatomy defective phenotype of sws¹ (Muhlig-Versen et al., 2005)
Phenotype Manifest In
Suppressor of
Statement Reference Scer\GAL4^loco.1.3/Mmus\NTE^Scer\UAS.cMa is a suppressor of CNS glial cell phenotype of sws¹ (Muhlig-Versen et al., 2005)
Additional Comments
Genetic Interactions
Statement Reference
Xenogenetic Interactions
Statement Reference
Complementation & Rescue Data
Rescues	sws^Scer\UAS.cMa/Scer\GAL4^loco.1.3 rescues sws¹ (Muhlig-Versen et al., 2005)
Partially rescues	Scer\GAL4^loco.1.3/crn^Scer\UAS.cEa partially rescues crn^unspecified (Edenfeld et al., 2006)
Fails to rescue	Scer\GAL4^loco.1.3/sws^{S985D.Scer\UAS} fails to rescue sws¹ (Muhlig-Versen et al., 2005)
Comments
Stocks ( 0 )

Notes on Origin
Discoverer

External Crossreferences & Linkouts
Other Crossreferences

Linkouts

Synonyms & Secondary IDs ( 1 )
Reported As
Symbol Synonym	Scer\GAL4^loco.1.3
Name Synonym
Secondary FlyBase IDs

References ( 7 )
Research paper	Schmidt et al., 2011, Glia 59(9): 1264--1272 Transcriptional regulation of peripheral glial cell differentiation in the embryonic nervous system of drosophila. [FBrf0214270] Edenfeld et al., 2006, Neuron 52(6): 969--980 The splicing factor crooked neck associates with the RNA-binding protein HOW to control glial cell maturation in Drosophila. [FBrf0194634] Muhlig-Versen et al., 2005, J. Neurosci. 25(11): 2865--2873 Loss of Swiss cheese/neuropathy target esterase activity causes disruption of phosphatidylcholine homeostasis and neuronal and glial death in adult Drosophila. [FBrf0184093] Jhaveri et al., 2004, Development 131(9): 1903--1912 Positioning sensory terminals in the olfactory lobe of Drosophila by Robo signaling. [FBrf0174568] Kuppers-Munther et al., 2004, Dev. Biol. 269(2): 459--478 A new culturing strategy optimises Drosophila primary cell cultures for structural and functional analyses. [FBrf0174530] Tschaepe et al., 2002, EMBO J. 21(23): 6367--6376 The neurodegeneration mutant lochrig interferes with cholesterol homeostasis and APPL processing. [FBrf0155731] Granderath et al., 2000, Mech. Dev. 91(1-2): 197--208 gcm and pointed synergistically control glial transcription of the Drosophila gene loco. [FBrf0127098]

Allele Scer\GAL4loco.1.3

Allele Scer\GAL4^loco.1.3