FlyBase Allele Report: Scer\GAL4[Ddc.PL]

ScerGAL4^Ddc.PL drives expression in a subset of the dopaminergic PPL2ab neurons and in the majority of the PAM neurons (includes MB-M3 and MB-MP1 neurons).

(Aso et al., 2012)

Expression observed in neurons that innervate the mushroom body horizontal lobes and the subsesophageal ganglion.

(Yarali and Gerber, 2010)

Expression in the midgut is found in a distinct group of Dh31-expressing enteroendocrine cells located at the junction region of the anterior midgut and the acid-secreting portion of the larval midgut. This junction region occurs at a conspicuous and characteristic U-shaped bend in the gut. These are referred to as the "midgut junction Dh31-expressing cells".

(Lajeunesse et al., 2010)

Expression is seen in dopaminergic and serotonergic neurons and their precursors, totalling 9-11 neurons per abdominal half-neuromere by larval stage L1. A precise pattern can be found in FBrf0160715.

(Landgraf et al., 2003)

Expression is observed in Ddc-expressing neurons.

(Li et al., 2000)

Marker for

dopaminergic neuron

(Joshi et al., 2004, Sykes et al., 2004, Monastirioti, 2003, Yang et al., 2003, Auluck et al., 2002, Feany and Bender, 2000, Li et al., 2000)

serotonergic neuron

(Joshi et al., 2004, Sykes et al., 2004, Monastirioti, 2003, Li et al., 2000)

Reflects expression of

Ddc

(Riemensperger et al., 2013, Aso et al., 2012, Chen et al., 2012, Agrawal et al., 2010, Alekseyenko et al., 2010, Haywood and Staveley, 2004, Joshi et al., 2004, Sykes et al., 2004, Landgraf et al., 2003, Monastirioti, 2003, Yang et al., 2003, Auluck et al., 2002, Haywood et al., 2002, Feany and Bender, 2000, Li et al., 2000)

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal behavior, with Trhn^UAS.cYa

(Yuan et al., 2006)

abnormal behavior | heat sensitive, with shi^1.UAS

(Alekseyenko et al., 2010, Zhang et al., 2007)

abnormal behavior | male, with Trhn^UAS.cDa

(Dierick and Greenspan, 2007)

abnormal body size, with Itpr^UAS.cVa, Itpr^sv35/Itpr^ug3

(Agrawal et al., 2009)

abnormal courtship behavior | :chemical conditional | heat sensitive, with shi^1.UAS

(Lee et al., 2008)

abnormal courtship behavior | female, with Hsap\ATXN3^{tr.Q78.UAS.Tag:HA}

(Kadener et al., 2006)

abnormal developmental rate, with Ns3^GD8441

(Kaplan et al., 2008)

abnormal developmental rate, with Ns3^{K350N.UAS.Venus}

(Hartl et al., 2013)

abnormal flight, with Ctet\tetX^{TNT-LC.UAS.cKa}

(Banerjee et al., 2004)

abnormal flight, with elgi^UAS.Tag:HA

(Tan et al., 2011)

abnormal grooming behavior, with Vmat^{UAS.Ex.Tag:HA}

(Chang et al., 2006)

abnormal locomotor behavior, with Hsap\LRRK2^{G2019S.UAS.Tag:FLAG}

(Liu et al., 2008)

abnormal locomotor behavior, with Hsap\LRRK2^UAS.Tag:FLAG

(Liu et al., 2008)

abnormal locomotor behavior, with Uch^GD11265

(Tran et al., 2018)

abnormal locomotor behavior | adult stage, with Buffy^RNAi.UAS

(M'Angale and Staveley, 2016)

abnormal locomotor behavior | adult stage, with Buffy^UAS.cQa

(M'Angale and Staveley, 2016)

abnormal locomotor behavior | adult stage, with DJ-1α^RNAi.UAS

(Faust et al., 2009)

abnormal locomotor behavior | adult stage, with Hsap\GBA1^{84GG.UAS.Tag:MYC,Tag:polyHis}

(Maor et al., 2016)

abnormal locomotor behavior | adult stage, with Hsap\LRRK2^{G2019S.UAS.Tag:FLAG}

(Liu et al., 2011)

abnormal locomotor behavior | adult stage, with Hsap\LRRK2^{G2019S.UAS.Tag:MYC}

(Ng et al., 2017, Ng et al., 2012)

abnormal locomotor behavior | adult stage, with Hsap\SNCA^A30P.UAS

(Riemensperger et al., 2013)

abnormal locomotor behavior | adult stage, with Hsap\SNCA^A53T.UAS.cKa

(Karpinar et al., 2009)

abnormal locomotor behavior | adult stage, with Hsap\SNCA^UAS.cFa

(M'Angale and Staveley, 2016, M'Angale and Staveley, 2016)

abnormal locomotor behavior | adult stage, with Lfg^HMS00225

(M'Angale and Staveley, 2016)

abnormal locomotor behavior | adult stage, with Lfg^KK104535

(M'Angale and Staveley, 2016)

abnormal locomotor behavior | adult stage, with MICU1^GD4927

(M'Angale and Staveley, 2017)

abnormal locomotor behavior | adult stage, with park^RNAi.UAS

(M'Angale and Staveley, 2017)

abnormal locomotor behavior | adult stage, with Pink1^RNAi.UAS.cYa

(M'Angale and Staveley, 2017)

abnormal locomotor behavior | adult stage, with Scer\GAL4^ple.PF, ple², ple^FS.UAS

(Riemensperger et al., 2011)

abnormal locomotor behavior | adult stage, with Vmat^{UAS.Ex.Tag:HA}

(Chang et al., 2006)

abnormal locomotor behavior | adult stage | conditional, with Hsap\SNCA^A53T.UAS.cKa

(Butler et al., 2012)

abnormal locomotor behavior | adult stage | progressive, with Atg6^GD11647

(M'Angale and Staveley, 2016)

abnormal locomotor behavior | adult stage | progressive, with Hsap\GBA1^{L444P.UAS.Tag:MYC,Tag:polyHis}

(Maor et al., 2013)

abnormal locomotor behavior | adult stage | progressive, with Hsap\GBA1^{N370S.UAS.Tag:MYC,Tag:polyHis}

(Maor et al., 2013)

abnormal locomotor behavior | adult stage | progressive, with Hsap\LRRK2^{G2019S.UAS.Tag:MYC}

(Ng et al., 2009)

abnormal locomotor behavior | adult stage | progressive, with Hsap\LRRK2^{R1441C.UAS.cIa.Tag:FLAG}

(Islam et al., 2016)

abnormal locomotor behavior | adult stage | progressive, with Hsap\LRRK2^{UAS.cIa.Tag:FLAG}

(Islam et al., 2016)

abnormal locomotor behavior | adult stage | progressive, with Hsap\LRRK2^{Y1699C.UAS.Tag:MYC}

(Ng et al., 2009)

abnormal locomotor behavior | adult stage | progressive, with Hsap\PRKN^R275W.UAS

(Wang et al., 2007)

abnormal locomotor behavior | adult stage | progressive, with Hsap\SNCA^E46K.UAS.cJa

(Jahromi et al., 2021)

abnormal locomotor behavior | adult stage | progressive, with Hsap\SNCA^UAS.cFa

(M'Angale and Staveley, 2016, Todd and Staveley, 2008)

abnormal locomotor behavior | adult stage | progressive, with Hsap\SNCA^UAS.cJb

(Jahromi et al., 2021)

abnormal locomotor behavior | adult stage | progressive, with Pi3K59F^KK107602

(M'Angale and Staveley, 2016)

abnormal locomotor behavior | chemical conditional, with Hsap\LRRK2^{G2019S.UAS.Tag:FLAG}

(Yang et al., 2012)

abnormal locomotor behavior | chemical conditional, with Hsap\LRRK2^UAS.Tag:FLAG

(Yang et al., 2012)

abnormal locomotor behavior | heat sensitive, with Hsap\TOR1A^ΔE.UAS

(Koh et al., 2004)

abnormal locomotor behavior | progressive, with Debcl^UAS.Tag:HA

(M'Angale and Staveley, 2016)

abnormal locomotor behavior | progressive, with Hsap\LRRK2^{G2019S.UAS.cLa.Tag:FLAG}

(Lin et al., 2010)

abnormal locomotor behavior | progressive, with Hsap\LRRK2^{G2019S.UAS.Tag:FLAG}

(Martin et al., 2014)

abnormal locomotor behavior | third instar larval stage, with Ctet\tetX^TNT-LC.UAS

(Suster et al., 2003)

abnormal locomotor rhythm, with Hsap\SNCA^A53T.UAS.cKa

(Gajula Balija et al., 2011)

abnormal locomotor rhythm, with Hsap\SNCA^TP.UAS.cKa

(Gajula Balija et al., 2011)

abnormal locomotor rhythm, with Hsap\SNCA^UAS.cKa

(Gajula Balija et al., 2011)

abnormal locomotor rhythm, with Scer\GAL4^ple.PF, ple², ple^FS.UAS

(Riemensperger et al., 2011)

abnormal locomotor rhythm | adult stage, with Hsap\SNCA^A30P.UAS

(Dhanushkodi et al., 2023)

abnormal locomotor rhythm | adult stage, with Hsap\SNCA^A53T.UAS

(Dhanushkodi et al., 2023)

abnormal memory, with Ctet\tetX^TNT-LC.UAS

(Sitaraman et al., 2008)

abnormal memory, with Ctet\tetX^TNT-LC.UAS, Scer\GAL4^ple.PF

(Sitaraman et al., 2008)

abnormal memory, with per^RNAi.PAS.UAS

(Chen et al., 2012)

abnormal memory, with Rcom\RT^A-cs2.UAS

(Chen et al., 2012)

abnormal memory, with w^RNAi.UAS.cKa

(Sitaraman et al., 2008)

abnormal memory | adult stage | :heat sensitive | conditional, with shi^1.UAS

(Vogt et al., 2014)

abnormal memory | adult stage | :heat sensitive | nutrition conditional, with TrpA1^UAS.(B).cKa

(Liu et al., 2012)

abnormal memory | adult stage | conditional, with Ctet\tetX^TNT-LC.UAS

(Sitaraman et al., 2017)

abnormal memory | adult stage | heat sensitive, with Scer\GAL80^ple.PK, TrpA1^UAS.(B).cKa

(Liu et al., 2012)

abnormal memory | adult stage | heat sensitive, with shi^1.UAS

(Liu et al., 2012)

abnormal memory | adult stage | heat sensitive, with shi^{ts1.IVS.p10.20xUAS}

(Shyu et al., 2017)

abnormal memory | adult stage | heat sensitive, with TrpA1^UAS.(B).cKa

(Shyu et al., 2017)

abnormal memory | heat sensitive, with TrpA1^UAS.(B).cKa

(Aso et al., 2012)

abnormal neuroanatomy, with Hsap\GPR37^UAS.cYa

(Yang et al., 2003)

abnormal neuroanatomy, with Hsap\LRRK2^{G2019S.UAS.cLa.Tag:FLAG}

(Lin et al., 2010)

abnormal neuroanatomy, with Hsap\LRRK2^{G2019S.UAS.Tag:FLAG}

(Liu et al., 2011)

abnormal neuroanatomy, with Hsap\SNCA^A30P.UAS

(Yang et al., 2003, Auluck et al., 2002)

abnormal neuroanatomy, with Hsap\SNCA^A53T.UAS

(Yang et al., 2003, Auluck et al., 2002)

abnormal neuroanatomy, with Hsap\SNCA^UAS.cFa

(Yang et al., 2003, Auluck et al., 2002)

abnormal neuroanatomy, with Hsc70-4^K71S.UAS

(Auluck et al., 2002)

abnormal neuroanatomy, with Pink1^RNAi.UAS.cWa

(Wang et al., 2006)

abnormal neuroanatomy | adult stage, with elgi^UAS.Tag:HA

(Tan et al., 2011)

abnormal neuroanatomy | adult stage, with Hsap\AP2M1^{TA.UAS.Tag:HA}

(Liu et al., 2021)

abnormal neuroanatomy | adult stage, with Hsap\AP2M1^UAS.Tag:HA

(Liu et al., 2021)

abnormal neuroanatomy | adult stage, with Hsap\LRRK2^GS.UAS.cLa

(Liu et al., 2021)

abnormal neuroanatomy | adult stage, with Hsap\LRRK2^{R1441C.UAS.cIa.Tag:FLAG}

(Islam et al., 2016)

abnormal neuroanatomy | adult stage, with Hsap\LRRK2^{UAS.cIa.Tag:FLAG}

(Islam et al., 2016)

abnormal neuroanatomy | adult stage, with Hsap\LRRK2^UAS.cLa

(Liu et al., 2021)

abnormal neuroanatomy | adult stage, with Hsap\SNCA^A53T.UAS.cKa

(Butler et al., 2012)

abnormal neuroanatomy | adult stage, with Hsap\SNCA^E46K.UAS.cJa

(Jahromi et al., 2021)

abnormal neuroanatomy | adult stage, with Hsap\SNCA^UAS.cJb

(Jahromi et al., 2021)

abnormal neuroanatomy | adult stage, with Septin4^UAS.cMa

(Muñoz-Soriano and Paricio, 2007)

abnormal neuroanatomy | adult stage | progressive, with DJ-1α^RNAi.UAS

(Faust et al., 2009)

abnormal neuroanatomy | adult stage | progressive, with Hsap\GBA1^{L444P.UAS.Tag:MYC,Tag:polyHis}

(Maor et al., 2016)

abnormal neuroanatomy | adult stage | progressive, with Hsap\GBA1^{N370S.UAS.Tag:MYC,Tag:polyHis}

(Maor et al., 2016)

abnormal neuroanatomy | adult stage | progressive, with Hsap\LRRK2^{G2019S.UAS.Tag:MYC}

(Ng et al., 2009)

abnormal neuroanatomy | adult stage | progressive, with Hsap\LRRK2^{G2385R.UAS.Tag:MYC}

(Ng et al., 2009)

abnormal neuroanatomy | adult stage | progressive, with Hsap\LRRK2^{Y1699C.UAS.Tag:MYC}

(Ng et al., 2009)

abnormal neuroanatomy | adult stage | progressive, with Hsap\PRKN^R275W.UAS

(Wang et al., 2007)

abnormal neuroanatomy | chemical conditional, with Hsap\LRRK2^{G2019S.UAS.Tag:FLAG}

(Yang et al., 2012)

abnormal neuroanatomy | chemical conditional, with Hsap\LRRK2^UAS.Tag:FLAG

(Yang et al., 2012)

abnormal neuroanatomy | progressive, with Hsap\LRRK2^{G2019S.UAS.cLa.Tag:FLAG}

(Martin et al., 2014)

abnormal neuroanatomy | progressive, with Hsap\LRRK2^{G2019S.UAS.Tag:FLAG}

(Martin et al., 2014)

abnormal neurophysiology, with Ctet\tetX^{TNT-LC.UAS.cKa}

(Banerjee et al., 2004)

abnormal neurophysiology, with Itpr^NIG.1063R

(Agrawal et al., 2010)

abnormal oxidative stress response | chemical conditional, with Usp30^NIG.3016R

(Bingol et al., 2014)

abnormal phototaxis, with Scer\GAL4^ple.PF, ple², ple^FS.UAS

(Riemensperger et al., 2011)

abnormal phototaxis, with Scer\GAL4^ple.PF, ple², ple^UAS.cFa

(Riemensperger et al., 2011)

abnormal sleep, with Scer\GAL4^ple.PF, ple², ple^FS.UAS

(Riemensperger et al., 2011)

abnormal sleep | adult stage, with anne^KK107621

(Dhanushkodi et al., 2023)

abnormal smell perception, with Scer\GAL4^ple.PF, ple², ple^FS.UAS

(Riemensperger et al., 2011)

abnormal smell perception | heat sensitive, with shi^1.UAS

(Kaun et al., 2011)

abnormal song, with Vmat^{UAS.Ex.Tag:HA}

(Chang et al., 2006)

abnormal starvation stress response | adult stage, with Hsap\SNCAIP^UAS.cLa

(Liu et al., 2012)

abnormal starvation stress response | female limited, with Same\Laz^UAS.cRa

(Ruiz et al., 2012)

abnormal stress response, with Mrp4^EP3177

(Huang and Haddad, 2007)

abnormal stress response, with Same\Laz^UAS.cRa

(Ruiz et al., 2012)

abnormal thermotaxis | adult stage | conditional, with Ctet\tetX^TNT-LC.UAS

(Sitaraman et al., 2017)

abnormal visual behavior, with Scer\GAL4^ple.PF, ple², ple^FS.UAS

(Riemensperger et al., 2011)

abnormal visual behavior, with Scer\GAL4^ple.PF, ple², ple^UAS.cFa

(Riemensperger et al., 2011)

abnormal visual behavior | heat sensitive, with shi^1.UAS

(Andretic et al., 2005)

chemical resistant, with Hsap\PRKN^WT.UAS

(Wang et al., 2007)

chemical resistant, with Usp30^NIG.3016R

(Bingol et al., 2014)

chemical resistant | female, with Same\Laz^UAS.cRa

(Ruiz et al., 2012)

chemical sensitive | adult stage, with Hsap\LRRK2^{G2019S.UAS.Tag:MYC}

(Ng et al., 2009)

chemical sensitive | adult stage, with Hsap\LRRK2^{G2385R.UAS.Tag:MYC}

(Ng et al., 2009)

chemical sensitive | adult stage, with Hsap\PRKN^R275W.UAS

(Wang et al., 2007)

chemical sensitive | male, with Same\Laz^UAS.cRa

(Ruiz et al., 2012)

decreased body size, with Ns3^GD8441

(Kaplan et al., 2008)

decreased cell death, with BacA\p35^UAS.cHa

(Sykes et al., 2004)

decreased cell number | adult stage, with Hsap\AP2M1^{TA.UAS.Tag:HA}

(Liu et al., 2021)

decreased cell number | adult stage, with Hsap\AP2M1^UAS.Tag:HA

(Liu et al., 2021)

decreased cell number | adult stage, with Hsap\LRRK2^{G2019S.UAS.Tag:MYC}

(Ng et al., 2017)

decreased cell number | adult stage, with Hsap\LRRK2^GS.UAS.cLa

(Liu et al., 2021)

decreased cell number | adult stage, with Hsap\LRRK2^{R1441C.UAS.cIa.Tag:FLAG}

(Islam et al., 2016)

decreased cell number | adult stage, with Hsap\LRRK2^{UAS.cIa.Tag:FLAG}

(Islam et al., 2016)

decreased cell number | adult stage, with Hsap\LRRK2^UAS.cLa

(Liu et al., 2021)

decreased cell number | adult stage, with Hsap\SNCA^E46K.UAS.cJa

(Jahromi et al., 2021)

decreased cell number | adult stage, with Hsap\SNCA^UAS.cJb

(Jahromi et al., 2021)

decreased cell number | adult stage, with srl^KK100201

(Ng et al., 2017)

decreased cell number | adult stage | progressive, with Hsap\GBA1^{L444P.UAS.Tag:MYC,Tag:polyHis}

(Maor et al., 2016)

decreased cell number | adult stage | progressive, with Hsap\GBA1^{N370S.UAS.Tag:MYC,Tag:polyHis}

(Maor et al., 2016)

decreased efficacy of learning | adult stage, with LIMK1^UAS.Tag:HA

(Zhuravlev et al., 2024)

decreased rate of adult locomotory behavior, with Arl8^NIG.7891R

(Szinyákovics et al., 2023)

decreased rate of adult locomotory behavior, with Arl8^UAS.cRa

(Szinyákovics et al., 2023)

decreased rate of adult locomotory behavior, with Rab2^KK107630

(Szinyákovics et al., 2023)

decreased rate of adult locomotory behavior, with Rab2^UAS.YFP

(Szinyákovics et al., 2023)

decreased rate of adult locomotory behavior | progressive, with Hsap\SNCA^A53T.UAS

(Szinyákovics et al., 2023)

decreased rate of adult locomotory behavior | progressive, with Rab7^GD11800

(Szinyákovics et al., 2023)

decreased rate of adult locomotory behavior | progressive, with Rab7^{Q67L.UASp.YFP}

(Szinyákovics et al., 2023)

decreased rate of movement, with Scer\GAL4^ple.PF, ple², ple^FS.UAS

(Riemensperger et al., 2011)

decreased rate of movement | adult stage, with Octα2R^HMC03079

(Nakagawa et al., 2022)

decreased sleep | adult stage, with mRpL15^GD11582

(Gokhale et al., 2021)

decreased sleep | adult stage, with mRpL40^GD16738

(Gokhale et al., 2021)

flightless | partially, with Gαq^RNAi.UAS.1f1

(Banerjee et al., 2006)

increased cell number | adult stage, with Hsap\SNCA^A53T.UAS.cKa

(Butler et al., 2012)

increased cell size | third instar larval stage, with Hsap\SNCAIP^UAS.cLa

(Liu et al., 2012)

increased rate of adult locomotory behavior, with anne^KK107621

(Dhanushkodi et al., 2023)

increased rate of adult locomotory behavior | progressive, with Arl8^Q75L.UAS

(Szinyákovics et al., 2023)

increased rate of adult locomotory behavior | progressive, with Rab2^{Q65L.UASp.YFP}

(Szinyákovics et al., 2023)

lethal, with EndoB^GD14693

(Zhu et al., 2013)

lethal, with sgg^UAS.cBa

(Trostnikov et al., 2019)

lethal - all die during pupal stage, with spg^{RNAi.1447-1632.UAS}

(Eguchi et al., 2013)

long lived, with Arl8^Q75L.UAS

(Szinyákovics et al., 2023)

long lived, with Buffy^UAS.cQa

(M'Angale and Staveley, 2016)

long lived, with Rab2^{Q65L.UASp.YFP}

(Szinyákovics et al., 2023)

long lived, with Same\Laz^UAS.cRa

(Ruiz et al., 2012)

long lived | chemical conditional, with Same\Laz^UAS.cRa

(Ruiz et al., 2012)

majority die during pupal stage, with Hsc70-5^KK100233

(Zhu et al., 2013)

partially lethal - majority die, with Pngl^PL, Pngl^UASp.cFa

(Hope et al., 2022)

partially lethal - majority live, with Mmus\Prnp^P101L.UAS

(Gavin et al., 2006)

short lived

(Haywood et al., 2002)

short lived, with Arl8^NIG.7891R

(Szinyákovics et al., 2023)

short lived, with Atg6^GD11647

(M'Angale and Staveley, 2016)

short lived, with Buffy^RNAi.UAS

(M'Angale and Staveley, 2016)

short lived, with Debcl^UAS.Tag:HA

(M'Angale and Staveley, 2016)

short lived, with Hsap\GBA1^{84GG.UAS.Tag:MYC,Tag:polyHis}

(Maor et al., 2016)

short lived, with Hsap\GBA1^{L444P.UAS.Tag:MYC,Tag:polyHis}

(Maor et al., 2016)

short lived, with Hsap\GBA1^{N370S.UAS.Tag:MYC,Tag:polyHis}

(Maor et al., 2016)

short lived, with Hsap\LRRK2^{G2019S.UAS.cMa}

(Macleod et al., 2013)

short lived, with Hsap\LRRK2^{G2019S.UAS.Tag:FLAG}

(Liu et al., 2011, Liu et al., 2008)

short lived, with Hsap\LRRK2^{G2019S.UAS.Tag:MYC}

(Ng et al., 2009)

short lived, with Hsap\LRRK2^{G2385R.UAS.Tag:MYC}

(Ng et al., 2009)

short lived, with Hsap\LRRK2^{R1441C.UAS.cIa.Tag:FLAG}

(Islam et al., 2016)

short lived, with Hsap\LRRK2^{UAS.cIa.Tag:FLAG}

(Islam et al., 2016)

short lived, with Hsap\LRRK2^UAS.Tag:FLAG

(Liu et al., 2008)

short lived, with Hsap\LRRK2^{Y1699C.UAS.Tag:MYC}

(Ng et al., 2009)

short lived, with Hsap\SNCA^A53T.UAS.cKa

(Butler et al., 2012, Karpinar et al., 2009)

short lived, with Hsap\SNCA^A53T.UAS

(Szinyákovics et al., 2023)

short lived, with Hsap\SNCA^A56P.UAS.cKa

(Karpinar et al., 2009)

short lived, with Hsap\SNCA^TP.UAS.cKa

(Karpinar et al., 2009)

short lived, with Hsap\SNCA^UAS.cFa

(M'Angale and Staveley, 2016, M'Angale and Staveley, 2016, M'Angale and Staveley, 2016)

short lived, with Lfg^HMS00225

(M'Angale and Staveley, 2016)

short lived, with Lfg^KK104535

(M'Angale and Staveley, 2016)

short lived, with MICU1^GD4927

(M'Angale and Staveley, 2017)

short lived, with Mmus\Prnp^P101L.UAS

(Gavin et al., 2006)

short lived, with park^RNAi.UAS

(M'Angale and Staveley, 2017)

short lived, with Pi3K59F^KK107602

(M'Angale and Staveley, 2016)

short lived, with Pink1^RNAi.UAS.cYa

(M'Angale and Staveley, 2017)

short lived, with Rab2^KK107630

(Szinyákovics et al., 2023)

short lived, with Rab7^GD11800

(Szinyákovics et al., 2023)

short lived, with Rab7^{Q67L.UASp.YFP}

(Szinyákovics et al., 2023)

short lived | chemical conditional, with Hsap\LRRK2^{G2019S.UAS.Tag:FLAG}

(Yang et al., 2012)

short lived | chemical conditional, with Hsap\LRRK2^UAS.Tag:FLAG

(Yang et al., 2012)

short lived | progressive, with Hsap\LRRK2^{G2019S.UAS.cLa.Tag:FLAG}

(Lin et al., 2010)

some die during larval stage, with Mmus\Prnp^P101L.UAS

(Gavin et al., 2006)

uncoordinated | adult stage, with Mmus\Prnp^P101L.UAS

(Gavin et al., 2006)

viable, with COX5B^GD6659

(Kemppainen et al., 2014)

viable, with COX6B^GD13061

(Kemppainen et al., 2014)

viable, with fh^RNAi.UAS.cLa

(Llorens et al., 2007)

viable, with fh^UAS.cLa

(Llorens et al., 2007)

Phenotype Manifest In

adult dopaminergic neuron | decreased number, with Hsap\SNCA^E46K.UAS.cJa

(Jahromi et al., 2021)

adult dopaminergic neuron | decreased number, with Hsap\SNCA^UAS.cJb

(Jahromi et al., 2021)

adult dopaminergic PAM neuron | adult stage, with Hsap\PRKN^R275W.UAS

(Wang et al., 2007)

autophagosome | adult stage, with Rab7^{Q67L.UASp.YFP}

(Szinyákovics et al., 2023)

axon | progressive, with Hsap\LRRK2^{G2019S.UAS.cLa.Tag:FLAG}

(Lin et al., 2010)

dendrite, with Hsap\LRRK2^{G2019S.UAS.cLa.Tag:FLAG}

(Lin et al., 2010)

dopamine neuron & adult brain, with Pink1^RNAi.UAS.cWa

(Wang et al., 2006)

dopaminergic neuron, with DJ-1α^RNAi.UAS

(Yang et al., 2005)

dopaminergic neuron, with Hsap\GPR37^UAS.cYa

(Yang et al., 2003)

dopaminergic neuron, with Hsap\LRRK2^{G2019S.UAS.cLa.Tag:FLAG}

(Lin et al., 2010)

dopaminergic neuron, with Hsap\LRRK2^{G2019S.UAS.Tag:FLAG}

(Liu et al., 2011, Liu et al., 2008)

dopaminergic neuron, with Hsap\LRRK2^{G2019S.UAS.Tag:MYC}

(Ng et al., 2012)

dopaminergic neuron, with Hsap\LRRK2^UAS.Tag:FLAG

(Liu et al., 2008)

dopaminergic neuron, with Hsap\SNCA^A30P.UAS

(Yang et al., 2003, Auluck et al., 2002)

dopaminergic neuron, with Hsap\SNCA^A53T.UAS

(Yang et al., 2003, Auluck et al., 2002)

dopaminergic neuron, with Hsap\SNCA^UAS.cFa

(Lee et al., 2009, Yang et al., 2003, Auluck et al., 2002)

dopaminergic neuron, with Hsc70-4^K71S.UAS

(Auluck et al., 2002)

dopaminergic neuron & adult brain, with Septin4^UAS.cMa

(Muñoz-Soriano and Paricio, 2007)

dopaminergic neuron | adult stage, with elgi^UAS.Tag:HA

(Tan et al., 2011)

dopaminergic neuron | adult stage, with Hsap\SNCA^A53T.UAS.cKa

(Butler et al., 2012)

dopaminergic neuron | adult stage | progressive, with DJ-1α^RNAi.UAS

(Faust et al., 2009)

dopaminergic neuron | adult stage | progressive, with Hsap\GBA1^{L444P.UAS.Tag:MYC,Tag:polyHis}

(Maor et al., 2016)

dopaminergic neuron | adult stage | progressive, with Hsap\GBA1^{N370S.UAS.Tag:MYC,Tag:polyHis}

(Maor et al., 2016)

dopaminergic neuron | increased number, with BacA\p35^UAS.cHa

(Sykes et al., 2004)

dopaminergic neuron | progressive, with Hsap\LRRK2^{G2019S.UAS.Tag:FLAG}

(Martin et al., 2014)

dopaminergic PAL neuron | adult stage, with Hsap\LRRK2^{R1441C.UAS.cIa.Tag:FLAG}

(Islam et al., 2016)

dopaminergic PAL neuron | adult stage, with Hsap\LRRK2^{UAS.cIa.Tag:FLAG}

(Islam et al., 2016)

dopaminergic PAL neuron | adult stage | chemical conditional, with Hsap\LRRK2^{G2385R.UAS.Tag:MYC}

(Ng et al., 2009)

dopaminergic PPL1 neuron, with Hsap\LRRK2^{G2019S.UAS.Tag:MYC}

(Ng et al., 2012)

dopaminergic PPL1 neuron | adult stage, with Hsap\LRRK2^{G2019S.UAS.Tag:MYC}

(Ng et al., 2017)

dopaminergic PPL1 neuron | adult stage, with Hsap\LRRK2^{R1441C.UAS.cIa.Tag:FLAG}

(Islam et al., 2016)

dopaminergic PPL1 neuron | adult stage, with Hsap\LRRK2^{UAS.cIa.Tag:FLAG}

(Islam et al., 2016)

dopaminergic PPL1 neuron | adult stage, with srl^KK100201

(Ng et al., 2017)

dopaminergic PPL1 neuron | adult stage | chemical conditional, with Hsap\LRRK2^{G2385R.UAS.Tag:MYC}

(Ng et al., 2009)

dopaminergic PPL1 neuron | adult stage | progressive, with Hsap\GBA1^{L444P.UAS.Tag:MYC,Tag:polyHis}

(Maor et al., 2016)

dopaminergic PPL1 neuron | adult stage | progressive, with Hsap\GBA1^{N370S.UAS.Tag:MYC,Tag:polyHis}

(Maor et al., 2016)

dopaminergic PPL1 neuron | adult stage | progressive, with Hsap\PRKN^R275W.UAS

(Wang et al., 2007)

dopaminergic PPL1 neuron | decreased number, with Hsap\AP2M1^{TA.UAS.Tag:HA}

(Liu et al., 2021)

dopaminergic PPL1 neuron | decreased number, with Hsap\LRRK2^GS.UAS.cLa

(Liu et al., 2021)

dopaminergic PPL2ab neuron | adult stage, with Hsap\LRRK2^{R1441C.UAS.cIa.Tag:FLAG}

(Islam et al., 2016)

dopaminergic PPL2ab neuron | adult stage, with Hsap\LRRK2^{UAS.cIa.Tag:FLAG}

(Islam et al., 2016)

dopaminergic PPM1 neuron | adult stage, with Hsap\LRRK2^{R1441C.UAS.cIa.Tag:FLAG}

(Islam et al., 2016)

dopaminergic PPM1 neuron | adult stage, with Hsap\LRRK2^{UAS.cIa.Tag:FLAG}

(Islam et al., 2016)

dopaminergic PPM1 neuron | adult stage | progressive, with Hsap\GBA1^{L444P.UAS.Tag:MYC,Tag:polyHis}

(Maor et al., 2016)

dopaminergic PPM1 neuron | adult stage | progressive, with Hsap\GBA1^{N370S.UAS.Tag:MYC,Tag:polyHis}

(Maor et al., 2016)

dopaminergic PPM1 neuron | adult stage | progressive, with Hsap\LRRK2^{G2019S.UAS.Tag:MYC}

(Ng et al., 2009)

dopaminergic PPM1 neuron | adult stage | progressive, with Hsap\LRRK2^{G2385R.UAS.Tag:MYC}

(Ng et al., 2009)

dopaminergic PPM1 neuron | adult stage | progressive, with Hsap\LRRK2^{Y1699C.UAS.Tag:MYC}

(Ng et al., 2009)

dopaminergic PPM1 neuron | decreased number, with Hsap\AP2M1^{TA.UAS.Tag:HA}

(Liu et al., 2021)

dopaminergic PPM1 neuron | decreased number, with Hsap\LRRK2^GS.UAS.cLa

(Liu et al., 2021)

dopaminergic PPM1 neuron | decreased number, with Hsap\LRRK2^UAS.cLa

(Liu et al., 2021)

dopaminergic PPM2 neuron | adult stage, with Hsap\LRRK2^{R1441C.UAS.cIa.Tag:FLAG}

(Islam et al., 2016)

dopaminergic PPM2 neuron | adult stage, with Hsap\LRRK2^{UAS.cIa.Tag:FLAG}

(Islam et al., 2016)

dopaminergic PPM2 neuron | adult stage | chemical conditional, with Hsap\LRRK2^{G2019S.UAS.Tag:MYC}

(Ng et al., 2009)

dopaminergic PPM2 neuron | adult stage | chemical conditional, with Hsap\LRRK2^{G2385R.UAS.Tag:MYC}

(Ng et al., 2009)

dopaminergic PPM2 neuron | adult stage | progressive, with Hsap\GBA1^{L444P.UAS.Tag:MYC,Tag:polyHis}

(Maor et al., 2016)

dopaminergic PPM2 neuron | adult stage | progressive, with Hsap\GBA1^{N370S.UAS.Tag:MYC,Tag:polyHis}

(Maor et al., 2016)

dopaminergic PPM2 neuron | decreased number, with Hsap\AP2M1^{TA.UAS.Tag:HA}

(Liu et al., 2021)

dopaminergic PPM2 neuron | decreased number, with Hsap\AP2M1^UAS.Tag:HA

(Liu et al., 2021)

dopaminergic PPM2 neuron | decreased number, with Hsap\LRRK2^GS.UAS.cLa

(Liu et al., 2021)

dopaminergic PPM2 neuron | decreased number, with Hsap\LRRK2^UAS.cLa

(Liu et al., 2021)

dopaminergic PPM3 neuron | adult stage | chemical conditional, with Hsap\LRRK2^{G2019S.UAS.Tag:MYC}

(Ng et al., 2009)

dopaminergic PPM3 neuron | adult stage | chemical conditional, with Hsap\LRRK2^{G2385R.UAS.Tag:MYC}

(Ng et al., 2009)

dopaminergic PPM3 neuron | adult stage | progressive, with Hsap\GBA1^{L444P.UAS.Tag:MYC,Tag:polyHis}

(Maor et al., 2016)

dopaminergic PPM3 neuron | adult stage | progressive, with Hsap\GBA1^{N370S.UAS.Tag:MYC,Tag:polyHis}

(Maor et al., 2016)

dopaminergic PPM3 neuron | adult stage | progressive, with Hsap\LRRK2^{G2019S.UAS.Tag:MYC}

(Ng et al., 2009)

dopaminergic PPM3 neuron | adult stage | progressive, with Hsap\LRRK2^{G2385R.UAS.Tag:MYC}

(Ng et al., 2009)

dopaminergic PPM3 neuron | adult stage | progressive, with Hsap\LRRK2^{Y1699C.UAS.Tag:MYC}

(Ng et al., 2009)

dopaminergic PPM3 neuron | decreased number, with Hsap\AP2M1^{TA.UAS.Tag:HA}

(Liu et al., 2021)

dopaminergic PPM3 neuron | decreased number, with Hsap\LRRK2^GS.UAS.cLa

(Liu et al., 2021)

dopaminergic PPM3 neuron | decreased number, with Hsap\LRRK2^UAS.cLa

(Liu et al., 2021)

dorso-lateral dopaminergic neuron, with Hsap\LRRK2^{G2019S.UAS.cLa.Tag:FLAG}

(Lin et al., 2010)

dorso-lateral dopaminergic neuron, with Hsap\SNCA^A30P.UAS

(Auluck et al., 2002)

dorso-lateral dopaminergic neuron, with Hsap\SNCA^A53T.UAS

(Auluck et al., 2002)

dorso-lateral dopaminergic neuron, with Hsap\SNCA^UAS.cFa

(Auluck et al., 2002)

embryonic/larval fat body | third instar larval stage, with Hsap\SNCAIP^UAS.cLa

(Liu et al., 2012)

flight muscle cell | adult stage, with srl^KK100201

(Ng et al., 2017)

indirect flight muscle cell, with Ctet\tetX^{TNT-LC.UAS.cKa}

(Banerjee et al., 2004)

lipid droplet, with Hsap\SNCAIP^UAS.cLa

(Liu et al., 2012)

mitochondrion, with Hsap\LRRK2^{G2019S.UAS.Tag:MYC}

(Ng et al., 2012)

mitochondrion | adult stage, with Hsap\LRRK2^{G2019S.UAS.Tag:MYC}

(Ng et al., 2017)

mitochondrion | adult stage, with srl^KK100201

(Ng et al., 2017)

neuron | progressive, with Hsap\LRRK2^{G2019S.UAS.cLa.Tag:FLAG}

(Lin et al., 2010)

wing, with Gαq^UAS.cRa

(Banerjee et al., 2006)

Detailed Description

Statement

Reference

Inhibition (using shi^{ts1.IVS.p10.20xUAS} at 32[o]C) of Scer\GAL4^Ddc.PL cells in adults significantly reduces 3-min associative olfactory water-reward memory, compared to controls; inhibition during acquisition alone also significantly reduces 3-hour and 24-hour memory.

Thermogenetic activation (using TrpA1^UAS.(B).cKa at 31[o]C) of Scer\GAL4^Ddc.PL cells in thirsty or water-sated adults, in combination with a paired odor, results in a significant increase in 3-min, 3-hour and 24-hour associative attractive olfactory memory, compared to controls.

(Shyu et al., 2017)

Inhibition (using Ctet\tetX^TNT.UAS) of a subset of Scer\GAL4^Ddc.PL cells (expression restricted using Scer\GAL80^ple.PK) does not affect latency of escape from heat or associative aversive (heat) place memory, compared to controls; the increases in escape latency and aversive memory due to unexpected high (41[o]C) temperature pre-exposure are significantly lower than those of controls.

(Sitaraman et al., 2017)

Inhibition (using Hsap\KCNJ2^UAS.EGFP) of Scer\GAL4^Ddc.PL cells, in combination with a Gal80[ts] transgene to restrict expression to the adult stage, does not affect aversive temperature or shock olfactory memory, compared to controls, and there is no effect on temperature avoidance.

(Galili et al., 2014)

Inhibition (using shi^1.UAS at 33[o]C) of Scer\GAL4^Ddc.PL cells in adults significantly reduces appetitive, but not aversive, 1-min visual memory, compared to controls; inhibition during training alone, but not testing, significantly reduces appetitive, but not aversive, 30-min visual memory, compared to controls; inhibition does not significantly affect sugar preference, compared to controls.

(Vogt et al., 2014)

Thermogenetic activation (using TrpA1^UAS.(B).cKa at 30[o]C) of Scer\GAL4^Ddc.PL cells in starved, but not fed, adults, in combination with a paired odor, results in a significant increase in 2-min associative attractive olfactory memory, compared to controls; this memory increase is still seen when activation is restricted to a smaller number of Scer\GAL4^Ddc.PL cells using Scer\GAL80^ple.PK, but not Scer\GAL80^R58E02; a significant increase in 12-hour memory also occurs when flies are starved or fed prior to training, but not if they are fed immediately before testing.

Inhibition (using shi^1.UAS at 32[o]C) of Scer\GAL4^Ddc.PL cells in adults fed immediately before training does not significantly affect 3-hour associative appetitive olfactory memory, compared to controls; inhibition before and during training, but not after training and during testing, significantly reduces 30-min associative appetitive olfactory memory, compared to controls; inhibition also significantly reduces short-term associative appetitive olfactory memory, compared to controls, but not when restricted to a smaller subset of Scer\GAL4^Ddc.PL cells using Scer\GAL80^R58E02; inhibition has no effect on naive sugar preference, compared to controls.

(Liu et al., 2012)

Animals expressing two copies of Scer\GAL4^Ddc.PL exhibit a greatly reduced lifespan, compared to wild-type. their locomotion remains normal.

(Haywood et al., 2002)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhanced by

Statement

Reference

Hsap\LRRK2^GS.UAS.cLa, Scer\GAL4^Ddc.PL has abnormal neuroanatomy | adult stage phenotype, enhanceable by Hsap\AP2M1^{TA.UAS.Tag:HA}, Scer\GAL4^Ddc.PL

(Liu et al., 2021)

Hsap\LRRK2^GS.UAS.cLa, Scer\GAL4^Ddc.PL has decreased cell number | adult stage phenotype, enhanceable by Hsap\AP2M1^{TA.UAS.Tag:HA}, Scer\GAL4^Ddc.PL

(Liu et al., 2021)

Hsap\LRRK2^UAS.cLa, Scer\GAL4^Ddc.PL has abnormal neuroanatomy | adult stage phenotype, enhanceable by Hsap\AP2M1^UAS.Tag:HA, Scer\GAL4^Ddc.PL

(Liu et al., 2021)

Hsap\LRRK2^UAS.cLa, Scer\GAL4^Ddc.PL has decreased cell number | adult stage phenotype, enhanceable by Hsap\AP2M1^UAS.Tag:HA, Scer\GAL4^Ddc.PL

(Liu et al., 2021)

Scer\GAL4^Ddc.PL, park^RNAi.UAS has short lived phenotype, enhanceable by Buffy^UAS.cQa, Scer\GAL4^Ddc.PL

(M'Angale and Staveley, 2017)

Scer\GAL4^Ddc.PL, park^RNAi.UAS has abnormal locomotor behavior | adult stage phenotype, enhanceable by Buffy^UAS.cQa, Scer\GAL4^Ddc.PL

(M'Angale and Staveley, 2017)

Hsap\SNCA^UAS.cFa, Scer\GAL4^Ddc.PL has abnormal locomotor behavior | adult stage phenotype, enhanceable by Buffy^RNAi.UAS, Scer\GAL4^Ddc.PL

(M'Angale and Staveley, 2016)

Hsap\SNCA^UAS.cFa, Scer\GAL4^Ddc.PL has short lived phenotype, enhanceable by Buffy^RNAi.UAS, Scer\GAL4^Ddc.PL

(M'Angale and Staveley, 2016)

Atg6^GD11647, Scer\GAL4^Ddc.PL has short lived phenotype, enhanceable by Buffy^UAS.cQa, Scer\GAL4^Ddc.PL

(M'Angale and Staveley, 2016)

Atg6^GD11647, Scer\GAL4^Ddc.PL has abnormal locomotor behavior | adult stage | progressive phenotype, enhanceable by Buffy^UAS.cQa, Scer\GAL4^Ddc.PL

(M'Angale and Staveley, 2016)

Hsap\SNCA^UAS.cFa, Scer\GAL4^Ddc.PL has short lived phenotype, enhanceable by Pi3K59F^KK107602, Scer\GAL4^Ddc.PL

(M'Angale and Staveley, 2016)

Hsap\SNCA^UAS.cFa, Scer\GAL4^Ddc.PL has short lived phenotype, enhanceable by Atg6^GD11647, Scer\GAL4^Ddc.PL

(M'Angale and Staveley, 2016)

Hsap\SNCA^UAS.cFa, Scer\GAL4^Ddc.PL has short lived phenotype, enhanceable by Debcl^UAS.Tag:HA, Scer\GAL4^Ddc.PL

(M'Angale and Staveley, 2016)

Hsap\SNCA^UAS.cFa, Scer\GAL4^Ddc.PL has abnormal locomotor behavior | adult stage phenotype, enhanceable by Debcl^UAS.Tag:HA, Scer\GAL4^Ddc.PL

(M'Angale and Staveley, 2016)

Hsap\LRRK2^{G2019S.UAS.Tag:MYC}, Scer\GAL4^Ddc.PL has abnormal locomotor behavior | adult stage phenotype, enhanceable by AMPKα^GD736, Scer\GAL4^Ddc.PL

(Ng et al., 2012)

Scer\GAL4^Ddc.PL, Septin4^UAS.cMa has abnormal neuroanatomy | adult stage phenotype, enhanceable by park^Δ21/park[+]

(Muñoz-Soriano and Paricio, 2007)

DJ-1α^RNAi.UAS, Scer\GAL4^Ddc.PL has increased cell death phenotype, enhanceable by Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^Ddc.PL

(Yang et al., 2005)

Hsap\GPR37^UAS.cYa, Scer\GAL4^Ddc.PL has abnormal neuroanatomy phenotype, enhanceable by park^RNAi.UAS, Scer\GAL4^Ddc.PL

(Yang et al., 2003)

Hsap\SNCA^UAS.cFa, Scer\GAL4^Ddc.PL has abnormal neuroanatomy phenotype, enhanceable by Hsc70-4^K71S.UAS, Scer\GAL4^Ddc.PL

(Auluck et al., 2002)

NOT Enhanced by

Statement

Reference

Hsap\LRRK2^UAS.cLa, Scer\GAL4^Ddc.PL has abnormal neuroanatomy | adult stage phenotype, non-enhanceable by Hsap\AP2M1^{TA.UAS.Tag:HA}, Scer\GAL4^Ddc.PL

(Liu et al., 2021)

Hsap\LRRK2^UAS.cLa, Scer\GAL4^Ddc.PL has decreased cell number | adult stage phenotype, non-enhanceable by Hsap\AP2M1^{TA.UAS.Tag:HA}, Scer\GAL4^Ddc.PL

(Liu et al., 2021)

Hsap\LRRK2^GS.UAS.cLa, Scer\GAL4^Ddc.PL has abnormal neuroanatomy | adult stage phenotype, non-enhanceable by Hsap\AP2M1^UAS.Tag:HA, Scer\GAL4^Ddc.PL

(Liu et al., 2021)

Hsap\LRRK2^GS.UAS.cLa, Scer\GAL4^Ddc.PL has decreased cell number | adult stage phenotype, non-enhanceable by Hsap\AP2M1^UAS.Tag:HA, Scer\GAL4^Ddc.PL

(Liu et al., 2021)

Hsap\SNCA^UAS.cFa, Scer\GAL4^Ddc.PL has abnormal locomotor behavior | adult stage | progressive phenotype, non-enhanceable by Pi3K59F^KK107602, Scer\GAL4^Ddc.PL

(M'Angale and Staveley, 2016)

Hsap\SNCA^UAS.cFa, Scer\GAL4^Ddc.PL has abnormal locomotor behavior | adult stage | progressive phenotype, non-enhanceable by Atg6^GD11647, Scer\GAL4^Ddc.PL

(M'Angale and Staveley, 2016)

Hsap\LRRK2^{G2019S.UAS.cLa.Tag:FLAG}, Scer\GAL4^Ddc.PL has abnormal neuroanatomy phenotype, non-enhanceable by sgg^UAS.cBa, Scer\GAL4^Ddc.PL

(Lin et al., 2010)

Suppressed by

Statement

Reference

Hsap\SNCA^A30P.UAS, Scer\GAL4^Ddc.PL has abnormal locomotor rhythm | adult stage phenotype, suppressible by anne^KK107621, Scer\GAL4^Ddc.PL

(Dhanushkodi et al., 2023)

Hsap\SNCA^A53T.UAS, Scer\GAL4^Ddc.PL has abnormal locomotor rhythm | adult stage phenotype, suppressible by anne^KK107621, Scer\GAL4^Ddc.PL

(Dhanushkodi et al., 2023)

Hsap\SNCA^A53T.UAS, Scer\GAL4^Ddc.PL has short lived phenotype, suppressible | partially by Rab2^{Q65L.UASp.YFP}, Scer\GAL4^Ddc.PL

(Szinyákovics et al., 2023)

Hsap\SNCA^A53T.UAS, Scer\GAL4^Ddc.PL has decreased rate of adult locomotory behavior | progressive phenotype, suppressible | partially by Rab2^{Q65L.UASp.YFP}, Scer\GAL4^Ddc.PL

(Szinyákovics et al., 2023)

Hsap\SNCA^A53T.UAS, Scer\GAL4^Ddc.PL has decreased rate of adult locomotory behavior | progressive phenotype, suppressible | partially by Arl8^Q75L.UAS, Scer\GAL4^Ddc.PL

(Szinyákovics et al., 2023)

MICU1^GD4927, Scer\GAL4^Ddc.PL has short lived phenotype, suppressible | partially by Buffy^UAS.cQa, Scer\GAL4^Ddc.PL

(M'Angale and Staveley, 2017)

MICU1^GD4927, Scer\GAL4^Ddc.PL has abnormal locomotor behavior | adult stage phenotype, suppressible | partially by Buffy^UAS.cQa, Scer\GAL4^Ddc.PL

(M'Angale and Staveley, 2017)

Pink1^RNAi.UAS.cYa, Scer\GAL4^Ddc.PL has short lived phenotype, suppressible | partially by Buffy^UAS.cQa, Scer\GAL4^Ddc.PL

(M'Angale and Staveley, 2017)

Pink1^RNAi.UAS.cYa, Scer\GAL4^Ddc.PL has abnormal locomotor behavior | adult stage phenotype, suppressible by Buffy^UAS.cQa, Scer\GAL4^Ddc.PL

(M'Angale and Staveley, 2017)

Hsap\LRRK2^{G2019S.UAS.Tag:MYC}, Scer\GAL4^Ddc.PL has abnormal locomotor behavior | adult stage phenotype, suppressible by AMPKα^TD.UAS, Scer\GAL4^Ddc.PL

(Ng et al., 2017)

Hsap\LRRK2^{G2019S.UAS.Tag:MYC}, Scer\GAL4^Ddc.PL has decreased cell number | adult stage phenotype, suppressible by AMPKα^TD.UAS, Scer\GAL4^Ddc.PL

(Ng et al., 2017)

Hsap\LRRK2^{G2019S.UAS.Tag:MYC}, Scer\GAL4^Ddc.PL has abnormal locomotor behavior | adult stage phenotype, suppressible | partially by srl^UAS.cTa, Scer\GAL4^Ddc.PL

(Ng et al., 2017)

Hsap\LRRK2^{G2019S.UAS.Tag:MYC}, Scer\GAL4^Ddc.PL has decreased cell number | adult stage phenotype, suppressible by srl^UAS.cTa, Scer\GAL4^Ddc.PL

(Ng et al., 2017)

Hsap\SNCA^UAS.cFa, Scer\GAL4^Ddc.PL has abnormal locomotor behavior | adult stage phenotype, suppressible by Buffy^UAS.cQa, Scer\GAL4^Ddc.PL

(M'Angale and Staveley, 2016)

Hsap\SNCA^UAS.cFa, Scer\GAL4^Ddc.PL has short lived phenotype, suppressible by Buffy^UAS.cQa, Scer\GAL4^Ddc.PL

(M'Angale and Staveley, 2016)

Lfg^KK104535, Scer\GAL4^Ddc.PL has short lived phenotype, suppressible by Buffy^UAS.cQa, Scer\GAL4^Ddc.PL

(M'Angale and Staveley, 2016)

Lfg^KK104535, Scer\GAL4^Ddc.PL has abnormal locomotor behavior | adult stage phenotype, suppressible by Buffy^UAS.cQa, Scer\GAL4^Ddc.PL

(M'Angale and Staveley, 2016)

Lfg^HMS00225, Scer\GAL4^Ddc.PL has short lived phenotype, suppressible by Buffy^UAS.cQa, Scer\GAL4^Ddc.PL

(M'Angale and Staveley, 2016)

Lfg^HMS00225, Scer\GAL4^Ddc.PL has abnormal locomotor behavior | adult stage phenotype, suppressible by Buffy^UAS.cQa, Scer\GAL4^Ddc.PL

(M'Angale and Staveley, 2016)

Pi3K59F^KK107602, Scer\GAL4^Ddc.PL has short lived phenotype, suppressible by Buffy^UAS.cQa, Scer\GAL4^Ddc.PL

(M'Angale and Staveley, 2016)

Pi3K59F^KK107602, Scer\GAL4^Ddc.PL has abnormal locomotor behavior | adult stage | progressive phenotype, suppressible by Buffy^UAS.cQa, Scer\GAL4^Ddc.PL

(M'Angale and Staveley, 2016)

Debcl^UAS.Tag:HA, Scer\GAL4^Ddc.PL has short lived phenotype, suppressible | partially by Buffy^UAS.cQa, Scer\GAL4^Ddc.PL

(M'Angale and Staveley, 2016)

Debcl^UAS.Tag:HA, Scer\GAL4^Ddc.PL has abnormal locomotor behavior | progressive phenotype, suppressible | partially by Buffy^UAS.cQa, Scer\GAL4^Ddc.PL

(M'Angale and Staveley, 2016)

Hsap\SNCA^UAS.cFa, Scer\GAL4^Ddc.PL has short lived phenotype, suppressible by Debcl^JF02429, Scer\GAL4^Ddc.PL

(M'Angale and Staveley, 2016)

Hsap\SNCA^UAS.cFa, Scer\GAL4^Ddc.PL has abnormal locomotor behavior | adult stage phenotype, suppressible by Debcl^JF02429, Scer\GAL4^Ddc.PL

(M'Angale and Staveley, 2016)

Scer\GAL4^Ddc.PL, Usp30^NIG.3016R has abnormal oxidative stress response | chemical conditional phenotype, suppressible by Hsap\USP30^UAS.cBa, Scer\GAL4^Ddc.PL

(Bingol et al., 2014)

Scer\GAL4^Ddc.PL, Usp30^NIG.3016R has chemical resistant phenotype, suppressible by Hsap\USP30^UAS.cBa, Scer\GAL4^Ddc.PL

(Bingol et al., 2014)

Hsap\LRRK2^{G2019S.UAS.Tag:FLAG}, Scer\GAL4^Ddc.PL has abnormal neuroanatomy | progressive phenotype, suppressible by Hsap\RPS15^T136A.UAS, Scer\GAL4^Ddc.PL

(Martin et al., 2014)

Hsap\LRRK2^{G2019S.UAS.Tag:FLAG}, Scer\GAL4^Ddc.PL has abnormal locomotor behavior | progressive phenotype, suppressible by Hsap\RPS15^T136A.UAS, Scer\GAL4^Ddc.PL

(Martin et al., 2014)

Hsap\LRRK2^{G2019S.UAS.cLa.Tag:FLAG}, Scer\GAL4^Ddc.PL has abnormal neuroanatomy | progressive phenotype, suppressible by Hsap\RPS15^T136A.UAS, Scer\GAL4^Ddc.PL

(Martin et al., 2014)

Hsap\SNCA^A53T.UAS.cKa, Scer\GAL4^Ddc.PL has increased cell number | adult stage phenotype, suppressible by Hsap\TRAP1^UAS.cBa, Scer\GAL4^Ddc.PL

(Butler et al., 2012)

Hsap\SNCA^A53T.UAS.cKa, Scer\GAL4^Ddc.PL has abnormal neuroanatomy | adult stage phenotype, suppressible by Hsap\TRAP1^UAS.cBa, Scer\GAL4^Ddc.PL

(Butler et al., 2012)

Hsap\SNCA^A53T.UAS.cKa, Scer\GAL4^Ddc.PL has abnormal gravitaxis | adult stage | conditional phenotype, suppressible | partially by Hsap\TRAP1^UAS.cBa, Scer\GAL4^Ddc.PL

(Butler et al., 2012)

Scer\GAL4^Ddc.PL, elgi^UAS.Tag:HA has abnormal neuroanatomy | adult stage phenotype, suppressible | partially by Hsap\PRKN^UAS.cYa, Scer\GAL4^Ddc.PL

(Tan et al., 2011)

Scer\GAL4^Ddc.PL, elgi^UAS.Tag:HA has abnormal flight phenotype, suppressible | partially by Hsap\PRKN^UAS.cYa, Scer\GAL4^Ddc.PL

(Tan et al., 2011)

Hsap\LRRK2^{G2019S.UAS.cLa.Tag:FLAG}, Scer\GAL4^Ddc.PL has abnormal neuroanatomy phenotype, suppressible by sgg^A81T.UAS, Scer\GAL4^Ddc.PL

(Lin et al., 2010)

Hsap\LRRK2^{G2019S.UAS.cLa.Tag:FLAG}, Scer\GAL4^Ddc.PL has abnormal locomotor behavior | progressive phenotype, suppressible by sgg^A81T.UAS, Scer\GAL4^Ddc.PL

(Lin et al., 2010)

Hsap\LRRK2^{G2019S.UAS.cLa.Tag:FLAG}, Scer\GAL4^Ddc.PL has short lived | progressive phenotype, suppressible by sgg^A81T.UAS, Scer\GAL4^Ddc.PL

(Lin et al., 2010)

DJ-1α^RNAi.UAS, Scer\GAL4^Ddc.PL has abnormal neuroanatomy | adult stage | progressive phenotype, suppressible by Hsap\PARK7^UAS.cYa, Scer\GAL4^Ddc.PL

(Faust et al., 2009)

DJ-1α^RNAi.UAS, Scer\GAL4^Ddc.PL has abnormal locomotor behavior | adult stage phenotype, suppressible by Hsap\PARK7^UAS.cYa, Scer\GAL4^Ddc.PL

(Faust et al., 2009)

Hsap\SNCA^UAS.cFa, Scer\GAL4^Ddc.PL has abnormal locomotor behavior | adult stage | progressive phenotype, suppressible by Pink1^UAS.cTa, Scer\GAL4^Ddc.PL

(Todd and Staveley, 2008)

Scer\GAL4^Ddc.PL, Septin4^UAS.cMa has abnormal neuroanatomy | adult stage phenotype, suppressible | partially by park^UAS.cMa/Scer\GAL4^Ddc.PL

(Muñoz-Soriano and Paricio, 2007)

Pink1^RNAi.UAS.cWa, Scer\GAL4^Ddc.PL has abnormal neuroanatomy phenotype, suppressible by Hsap\PINK1^UAS.Tag:FLAG, Scer\GAL4^Ddc.PL

(Wang et al., 2006)

DJ-1α^RNAi.UAS, Scer\GAL4^Ddc.PL has increased cell death phenotype, suppressible by Pi3K92E^UAS.Tag:MYC, Scer\GAL4^Ddc.PL

(Yang et al., 2005)

Hsap\SNCA^A30P.UAS, Scer\GAL4^Ddc.PL has abnormal neuroanatomy phenotype, suppressible by Hsap\PRKN^UAS.cYa, Scer\GAL4^Ddc.PL

(Yang et al., 2003)

Hsap\SNCA^UAS.cFa, Scer\GAL4^Ddc.PL has abnormal neuroanatomy phenotype, suppressible by Hsap\PRKN^UAS.cYa, Scer\GAL4^Ddc.PL

(Yang et al., 2003)

Hsap\SNCA^A53T.UAS, Scer\GAL4^Ddc.PL has abnormal neuroanatomy phenotype, suppressible by Hsap\PRKN^UAS.cYa, Scer\GAL4^Ddc.PL

(Yang et al., 2003)

Hsap\GPR37^UAS.cYa, Scer\GAL4^Ddc.PL has abnormal neuroanatomy phenotype, suppressible by Hsap\PRKN^UAS.cYa, Scer\GAL4^Ddc.PL

(Yang et al., 2003)

Hsap\SNCA^UAS.cFa, Scer\GAL4^Ddc.PL has abnormal neuroanatomy phenotype, suppressible by Hsap\HSPA1L^UAS.cWa, Scer\GAL4^Ddc.PL

(Auluck et al., 2002)

NOT suppressed by

Statement

Reference

Hsap\SNCA^A53T.UAS, Scer\GAL4^Ddc.PL has short lived phenotype, non-suppressible by Arl8^Q75L.UAS, Scer\GAL4^Ddc.PL

(Szinyákovics et al., 2023)

Scer\GAL4^Ddc.PL, srl^KK100201 has decreased cell number | adult stage phenotype, non-suppressible by AMPKα^TD.UAS, Scer\GAL4^Ddc.PL

(Ng et al., 2017)

Hsap\LRRK2^{G2019S.UAS.Tag:MYC}, Scer\GAL4^Ddc.PL has abnormal locomotor behavior | adult stage phenotype, non-suppressible by AMPKα^TD.UAS/srl^KK100201, Scer\GAL4^Ddc.PL

(Ng et al., 2017)

Hsap\LRRK2^{G2019S.UAS.Tag:MYC}, Scer\GAL4^Ddc.PL has decreased cell number | adult stage phenotype, non-suppressible by AMPKα^TD.UAS/srl^KK100201, Scer\GAL4^Ddc.PL

(Ng et al., 2017)

Hsap\LRRK2^{G2019S.UAS.Tag:FLAG}, Scer\GAL4^Ddc.PL has abnormal locomotor behavior | progressive phenotype, non-suppressible by Hsap\RPS15^UAS.cMa, Scer\GAL4^Ddc.PL

(Martin et al., 2014)

Hsap\LRRK2^{G2019S.UAS.Tag:FLAG}, Scer\GAL4^Ddc.PL has abnormal neuroanatomy | progressive phenotype, non-suppressible by Hsap\RPS15^UAS.cMa, Scer\GAL4^Ddc.PL

(Martin et al., 2014)

Hsap\SNCA^A53T.UAS.cKa, Scer\GAL4^Ddc.PL has short lived phenotype, non-suppressible by Hsap\TRAP1^UAS.cBa, Scer\GAL4^Ddc.PL

(Butler et al., 2012)

Hsap\LRRK2^{G2019S.UAS.cLa.Tag:FLAG}, Scer\GAL4^Ddc.PL has abnormal neuroanatomy phenotype, non-suppressible by sgg^UAS.cBa, Scer\GAL4^Ddc.PL

(Lin et al., 2010)

Enhancer of

Statement

Reference

Hsap\AP2M1^{TA.UAS.Tag:HA}, Scer\GAL4^Ddc.PL is an enhancer of abnormal neuroanatomy | adult stage phenotype of Hsap\LRRK2^GS.UAS.cLa, Scer\GAL4^Ddc.PL

(Liu et al., 2021)

Hsap\AP2M1^{TA.UAS.Tag:HA}, Scer\GAL4^Ddc.PL is an enhancer of decreased cell number | adult stage phenotype of Hsap\LRRK2^GS.UAS.cLa, Scer\GAL4^Ddc.PL

(Liu et al., 2021)

Hsap\AP2M1^UAS.Tag:HA, Scer\GAL4^Ddc.PL is an enhancer of abnormal neuroanatomy | adult stage phenotype of Hsap\LRRK2^UAS.cLa, Scer\GAL4^Ddc.PL

(Liu et al., 2021)

Hsap\AP2M1^UAS.Tag:HA, Scer\GAL4^Ddc.PL is an enhancer of decreased cell number | adult stage phenotype of Hsap\LRRK2^UAS.cLa, Scer\GAL4^Ddc.PL

(Liu et al., 2021)

Buffy^UAS.cQa, Scer\GAL4^Ddc.PL is an enhancer of abnormal locomotor behavior | adult stage phenotype of Scer\GAL4^Ddc.PL, park^RNAi.UAS

(M'Angale and Staveley, 2017)

Buffy^UAS.cQa, Scer\GAL4^Ddc.PL is an enhancer of short lived phenotype of Scer\GAL4^Ddc.PL, park^RNAi.UAS

(M'Angale and Staveley, 2017)

Buffy^RNAi.UAS/Scer\GAL4^Ddc.PL is an enhancer of visible phenotype of Hsap\SNCA^UAS.cFa, Scer\GAL4^GMR.PU

(M'Angale and Staveley, 2016)

Buffy^RNAi.UAS, Scer\GAL4^Ddc.PL is an enhancer of abnormal locomotor behavior | adult stage phenotype of Hsap\SNCA^UAS.cFa, Scer\GAL4^Ddc.PL

(M'Angale and Staveley, 2016)

Buffy^RNAi.UAS, Scer\GAL4^Ddc.PL is an enhancer of short lived phenotype of Hsap\SNCA^UAS.cFa, Scer\GAL4^Ddc.PL

(M'Angale and Staveley, 2016)

Buffy^UAS.cQa, Scer\GAL4^Ddc.PL is an enhancer of short lived phenotype of Atg6^GD11647, Scer\GAL4^Ddc.PL

(M'Angale and Staveley, 2016)

Buffy^UAS.cQa, Scer\GAL4^Ddc.PL is an enhancer of abnormal locomotor behavior | adult stage | progressive phenotype of Atg6^GD11647, Scer\GAL4^Ddc.PL

(M'Angale and Staveley, 2016)

Pi3K59F^KK107602, Scer\GAL4^Ddc.PL is an enhancer of short lived phenotype of Hsap\SNCA^UAS.cFa, Scer\GAL4^Ddc.PL

(M'Angale and Staveley, 2016)

Atg6^GD11647, Scer\GAL4^Ddc.PL is an enhancer of short lived phenotype of Hsap\SNCA^UAS.cFa, Scer\GAL4^Ddc.PL

(M'Angale and Staveley, 2016)

Debcl^UAS.Tag:HA, Scer\GAL4^Ddc.PL is an enhancer of short lived phenotype of Hsap\SNCA^UAS.cFa, Scer\GAL4^Ddc.PL

(M'Angale and Staveley, 2016)

Debcl^UAS.Tag:HA, Scer\GAL4^Ddc.PL is an enhancer of abnormal locomotor behavior | adult stage phenotype of Hsap\SNCA^UAS.cFa, Scer\GAL4^Ddc.PL

(M'Angale and Staveley, 2016)

AMPKα^GD736, Scer\GAL4^Ddc.PL is an enhancer of abnormal locomotor behavior | adult stage phenotype of Hsap\LRRK2^{G2019S.UAS.Tag:MYC}, Scer\GAL4^Ddc.PL

(Ng et al., 2012)

Hsap\PRKN^R275W.UAS/Scer\GAL4^Ddc.PL is an enhancer of abnormal locomotor behavior | adult stage phenotype of park¹

(Wang et al., 2007)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^Ddc.PL is an enhancer of increased cell death phenotype of DJ-1α^RNAi.UAS, Scer\GAL4^Ddc.PL

(Yang et al., 2005)

park^RNAi.UAS, Scer\GAL4^Ddc.PL is an enhancer of abnormal neuroanatomy phenotype of Hsap\GPR37^UAS.cYa, Scer\GAL4^Ddc.PL

(Yang et al., 2003)

Hsc70-4^K71S.UAS, Scer\GAL4^Ddc.PL is an enhancer of abnormal neuroanatomy phenotype of Hsap\SNCA^UAS.cFa, Scer\GAL4^Ddc.PL

(Auluck et al., 2002)

NOT Enhancer of

Statement

Reference

Hsap\AP2M1^{TA.UAS.Tag:HA}, Scer\GAL4^Ddc.PL is a non-enhancer of abnormal neuroanatomy | adult stage phenotype of Hsap\LRRK2^UAS.cLa, Scer\GAL4^Ddc.PL

(Liu et al., 2021)

Hsap\AP2M1^{TA.UAS.Tag:HA}, Scer\GAL4^Ddc.PL is a non-enhancer of decreased cell number | adult stage phenotype of Hsap\LRRK2^UAS.cLa, Scer\GAL4^Ddc.PL

(Liu et al., 2021)

Hsap\AP2M1^UAS.Tag:HA, Scer\GAL4^Ddc.PL is a non-enhancer of abnormal neuroanatomy | adult stage phenotype of Hsap\LRRK2^GS.UAS.cLa, Scer\GAL4^Ddc.PL

(Liu et al., 2021)

Hsap\AP2M1^UAS.Tag:HA, Scer\GAL4^Ddc.PL is a non-enhancer of decreased cell number | adult stage phenotype of Hsap\LRRK2^GS.UAS.cLa, Scer\GAL4^Ddc.PL

(Liu et al., 2021)

Pi3K59F^KK107602, Scer\GAL4^Ddc.PL is a non-enhancer of abnormal locomotor behavior | adult stage | progressive phenotype of Hsap\SNCA^UAS.cFa, Scer\GAL4^Ddc.PL

(M'Angale and Staveley, 2016)

Atg6^GD11647, Scer\GAL4^Ddc.PL is a non-enhancer of abnormal locomotor behavior | adult stage | progressive phenotype of Hsap\SNCA^UAS.cFa, Scer\GAL4^Ddc.PL

(M'Angale and Staveley, 2016)

sgg^UAS.cBa, Scer\GAL4^Ddc.PL is a non-enhancer of abnormal neuroanatomy phenotype of Hsap\LRRK2^{G2019S.UAS.cLa.Tag:FLAG}, Scer\GAL4^Ddc.PL

(Lin et al., 2010)

Suppressor of

Statement

Reference

anne^KK107621, Scer\GAL4^Ddc.PL is a suppressor of abnormal locomotor rhythm | adult stage phenotype of Hsap\SNCA^A30P.UAS, Scer\GAL4^Ddc.PL

(Dhanushkodi et al., 2023)

anne^KK107621, Scer\GAL4^Ddc.PL is a suppressor of abnormal locomotor rhythm | adult stage phenotype of Hsap\SNCA^A53T.UAS, Scer\GAL4^Ddc.PL

(Dhanushkodi et al., 2023)

Rab2^{Q65L.UASp.YFP}, Scer\GAL4^Ddc.PL is a suppressor | partially of short lived phenotype of Hsap\SNCA^A53T.UAS, Scer\GAL4^Ddc.PL

(Szinyákovics et al., 2023)

Rab2^{Q65L.UASp.YFP}, Scer\GAL4^Ddc.PL is a suppressor | partially of decreased rate of adult locomotory behavior | progressive phenotype of Hsap\SNCA^A53T.UAS, Scer\GAL4^Ddc.PL

(Szinyákovics et al., 2023)

Arl8^Q75L.UAS, Scer\GAL4^Ddc.PL is a suppressor | partially of decreased rate of adult locomotory behavior | progressive phenotype of Hsap\SNCA^A53T.UAS, Scer\GAL4^Ddc.PL

(Szinyákovics et al., 2023)

NUCB1^NIG.32190R/Scer\GAL4^Ddc.PL is a suppressor of visible | adult stage phenotype of Itpr^wc703/Itpr^ug3

(Balasubramanian and Srinivasan, 2020)

Orai[+], NUCB1^NIG.32190R, Orai^k11505, Scer\GAL4^Ddc.PL is a suppressor of abnormal flight phenotype of Itpr^wc703/Itpr^ug3

(Balasubramanian and Srinivasan, 2020)

NUCB1^NIG.32190R/Scer\GAL4^Ddc.PL is a suppressor of visible | adult stage phenotype of Itpr^wc361/Itpr^ug3

(Balasubramanian and Srinivasan, 2020)

Orai[+], NUCB1^NIG.32190R, Orai^k11505, Scer\GAL4^Ddc.PL is a suppressor of abnormal flight phenotype of Itpr^wc361/Itpr^ug3

(Balasubramanian and Srinivasan, 2020)

Buffy^UAS.cQa, Scer\GAL4^Ddc.PL is a suppressor | partially of short lived phenotype of MICU1^GD4927, Scer\GAL4^Ddc.PL

(M'Angale and Staveley, 2017)

Buffy^UAS.cQa, Scer\GAL4^Ddc.PL is a suppressor | partially of abnormal locomotor behavior | adult stage phenotype of MICU1^GD4927, Scer\GAL4^Ddc.PL

(M'Angale and Staveley, 2017)

Buffy^UAS.cQa, Scer\GAL4^Ddc.PL is a suppressor | partially of short lived phenotype of Pink1^RNAi.UAS.cYa, Scer\GAL4^Ddc.PL

(M'Angale and Staveley, 2017)

Buffy^UAS.cQa, Scer\GAL4^Ddc.PL is a suppressor of abnormal locomotor behavior | adult stage phenotype of Pink1^RNAi.UAS.cYa, Scer\GAL4^Ddc.PL

(M'Angale and Staveley, 2017)

AMPKα^TD.UAS, Scer\GAL4^Ddc.PL is a suppressor of abnormal locomotor behavior | adult stage phenotype of Hsap\LRRK2^{G2019S.UAS.Tag:MYC}, Scer\GAL4^Ddc.PL

(Ng et al., 2017)

AMPKα^TD.UAS, Scer\GAL4^Ddc.PL is a suppressor of decreased cell number | adult stage phenotype of Hsap\LRRK2^{G2019S.UAS.Tag:MYC}, Scer\GAL4^Ddc.PL

(Ng et al., 2017)

srl^UAS.cTa, Scer\GAL4^Ddc.PL is a suppressor | partially of abnormal locomotor behavior | adult stage phenotype of Hsap\LRRK2^{G2019S.UAS.Tag:MYC}, Scer\GAL4^Ddc.PL

(Ng et al., 2017)

srl^UAS.cTa, Scer\GAL4^Ddc.PL is a suppressor of decreased cell number | adult stage phenotype of Hsap\LRRK2^{G2019S.UAS.Tag:MYC}, Scer\GAL4^Ddc.PL

(Ng et al., 2017)

Buffy^UAS.cQa, Scer\GAL4^Ddc.PL is a suppressor of abnormal locomotor behavior | adult stage phenotype of Hsap\SNCA^UAS.cFa, Scer\GAL4^Ddc.PL

(M'Angale and Staveley, 2016)

Buffy^UAS.cQa, Scer\GAL4^Ddc.PL is a suppressor of short lived phenotype of Hsap\SNCA^UAS.cFa, Scer\GAL4^Ddc.PL

(M'Angale and Staveley, 2016)

Buffy^UAS.cQa/Scer\GAL4^Ddc.PL is a suppressor of visible phenotype of Hsap\SNCA^UAS.cFa, Scer\GAL4^GMR.PU

(M'Angale and Staveley, 2016)

Buffy^UAS.cQa, Scer\GAL4^Ddc.PL is a suppressor of short lived phenotype of Lfg^KK104535, Scer\GAL4^Ddc.PL

(M'Angale and Staveley, 2016)

Buffy^UAS.cQa, Scer\GAL4^Ddc.PL is a suppressor of abnormal locomotor behavior | adult stage phenotype of Lfg^KK104535, Scer\GAL4^Ddc.PL

(M'Angale and Staveley, 2016)

Buffy^UAS.cQa/Scer\GAL4^Ddc.PL is a suppressor of visible | adult stage phenotype of Lfg^KK104535, Scer\GAL4^GMR.PF

(M'Angale and Staveley, 2016)

Buffy^UAS.cQa, Scer\GAL4^Ddc.PL is a suppressor of short lived phenotype of Lfg^HMS00225, Scer\GAL4^Ddc.PL

(M'Angale and Staveley, 2016)

Buffy^UAS.cQa, Scer\GAL4^Ddc.PL is a suppressor of abnormal locomotor behavior | adult stage phenotype of Lfg^HMS00225, Scer\GAL4^Ddc.PL

(M'Angale and Staveley, 2016)

Buffy^UAS.cQa/Scer\GAL4^Ddc.PL is a suppressor of visible | adult stage phenotype of Lfg^HMS00225, Scer\GAL4^GMR.PF

(M'Angale and Staveley, 2016)

Buffy^UAS.cQa, Scer\GAL4^Ddc.PL is a suppressor of short lived phenotype of Pi3K59F^KK107602, Scer\GAL4^Ddc.PL

(M'Angale and Staveley, 2016)

Buffy^UAS.cQa, Scer\GAL4^Ddc.PL is a suppressor of abnormal locomotor behavior | adult stage | progressive phenotype of Pi3K59F^KK107602, Scer\GAL4^Ddc.PL

(M'Angale and Staveley, 2016)

Buffy^UAS.cQa, Scer\GAL4^Ddc.PL is a suppressor | partially of short lived phenotype of Debcl^UAS.Tag:HA, Scer\GAL4^Ddc.PL

(M'Angale and Staveley, 2016)

Buffy^UAS.cQa, Scer\GAL4^Ddc.PL is a suppressor | partially of abnormal locomotor behavior | progressive phenotype of Debcl^UAS.Tag:HA, Scer\GAL4^Ddc.PL

(M'Angale and Staveley, 2016)

Debcl^JF02429, Scer\GAL4^Ddc.PL is a suppressor of short lived phenotype of Hsap\SNCA^UAS.cFa, Scer\GAL4^Ddc.PL

(M'Angale and Staveley, 2016)

Debcl^JF02429, Scer\GAL4^Ddc.PL is a suppressor of abnormal locomotor behavior | adult stage phenotype of Hsap\SNCA^UAS.cFa, Scer\GAL4^Ddc.PL

(M'Angale and Staveley, 2016)

Hsap\USP30^UAS.cBa, Scer\GAL4^Ddc.PL is a suppressor of abnormal oxidative stress response | chemical conditional phenotype of Scer\GAL4^Ddc.PL, Usp30^NIG.3016R

(Bingol et al., 2014)

Hsap\USP30^UAS.cBa, Scer\GAL4^Ddc.PL is a suppressor of chemical resistant phenotype of Scer\GAL4^Ddc.PL, Usp30^NIG.3016R

(Bingol et al., 2014)

Hsap\RPS15^T136A.UAS, Scer\GAL4^Ddc.PL is a suppressor of abnormal neuroanatomy | progressive phenotype of Hsap\LRRK2^{G2019S.UAS.Tag:FLAG}, Scer\GAL4^Ddc.PL

(Martin et al., 2014)

Hsap\RPS15^T136A.UAS, Scer\GAL4^Ddc.PL is a suppressor of abnormal locomotor behavior | progressive phenotype of Hsap\LRRK2^{G2019S.UAS.Tag:FLAG}, Scer\GAL4^Ddc.PL

(Martin et al., 2014)

Hsap\RPS15^T136A.UAS, Scer\GAL4^Ddc.PL is a suppressor of abnormal neuroanatomy | progressive phenotype of Hsap\LRRK2^{G2019S.UAS.cLa.Tag:FLAG}, Scer\GAL4^Ddc.PL

(Martin et al., 2014)

Hsap\TRAP1^UAS.cBa, Scer\GAL4^Ddc.PL is a suppressor of increased cell number | adult stage phenotype of Hsap\SNCA^A53T.UAS.cKa, Scer\GAL4^Ddc.PL

(Butler et al., 2012)

Hsap\TRAP1^UAS.cBa, Scer\GAL4^Ddc.PL is a suppressor of abnormal neuroanatomy | adult stage phenotype of Hsap\SNCA^A53T.UAS.cKa, Scer\GAL4^Ddc.PL

(Butler et al., 2012)

Hsap\TRAP1^UAS.cBa, Scer\GAL4^Ddc.PL is a suppressor | partially of abnormal gravitaxis | adult stage | conditional phenotype of Hsap\SNCA^A53T.UAS.cKa, Scer\GAL4^Ddc.PL

(Butler et al., 2012)

Hsap\PRKN^UAS.cYa, Scer\GAL4^Ddc.PL is a suppressor | partially of abnormal neuroanatomy | adult stage phenotype of Scer\GAL4^Ddc.PL, elgi^UAS.Tag:HA

(Tan et al., 2011)

Hsap\PRKN^UAS.cYa, Scer\GAL4^Ddc.PL is a suppressor | partially of abnormal flight phenotype of Scer\GAL4^Ddc.PL, elgi^UAS.Tag:HA

(Tan et al., 2011)

Stim^UAS.cAa/Scer\GAL4^Ddc.PL is a suppressor of visible phenotype of Itpr^ug3/Itpr^ka1091

(Agrawal et al., 2010)

Stim^UAS.cAa/Scer\GAL4^Ddc.PL is a suppressor of abnormal neurophysiology phenotype of Itpr^ug3/Itpr^ka1091

(Agrawal et al., 2010)

Stim^UAS.cAa/Scer\GAL4^Ddc.PL is a suppressor of abnormal flight phenotype of Itpr^ug3/Itpr^ka1091

(Agrawal et al., 2010)

sgg^A81T.UAS, Scer\GAL4^Ddc.PL is a suppressor of abnormal neuroanatomy phenotype of Hsap\LRRK2^{G2019S.UAS.cLa.Tag:FLAG}, Scer\GAL4^Ddc.PL

(Lin et al., 2010)

sgg^A81T.UAS, Scer\GAL4^Ddc.PL is a suppressor of abnormal locomotor behavior | progressive phenotype of Hsap\LRRK2^{G2019S.UAS.cLa.Tag:FLAG}, Scer\GAL4^Ddc.PL

(Lin et al., 2010)

sgg^A81T.UAS, Scer\GAL4^Ddc.PL is a suppressor of short lived | progressive phenotype of Hsap\LRRK2^{G2019S.UAS.cLa.Tag:FLAG}, Scer\GAL4^Ddc.PL

(Lin et al., 2010)

Hsap\PARK7^UAS.cYa, Scer\GAL4^Ddc.PL is a suppressor of abnormal neuroanatomy | adult stage | progressive phenotype of DJ-1α^RNAi.UAS, Scer\GAL4^Ddc.PL

(Faust et al., 2009)

Hsap\PARK7^UAS.cYa, Scer\GAL4^Ddc.PL is a suppressor of abnormal locomotor behavior | adult stage phenotype of DJ-1α^RNAi.UAS, Scer\GAL4^Ddc.PL

(Faust et al., 2009)

Pink1^UAS.cTa, Scer\GAL4^Ddc.PL is a suppressor of abnormal locomotor behavior | adult stage | progressive phenotype of Hsap\SNCA^UAS.cFa, Scer\GAL4^Ddc.PL

(Todd and Staveley, 2008)

park^UAS.cMa/Scer\GAL4^Ddc.PL is a suppressor | partially of abnormal neuroanatomy | adult stage phenotype of Scer\GAL4^Ddc.PL, Septin4^UAS.cMa

(Muñoz-Soriano and Paricio, 2007)

Gαq^UAS.cRa/Scer\GAL4^Ddc.PL is a suppressor | partially of flightless | partially phenotype of Gα49B[+]/Gαq^221c, Itpr^wc703/Itpr^wc361

(Banerjee et al., 2006)

Gαq^UAS.cRa/Scer\GAL4^Ddc.PL is a suppressor | partially of abnormal neurophysiology phenotype of Gα49B[+]/Gαq^221c, Itpr^wc703/Itpr^wc361

(Banerjee et al., 2006)

Hsap\PINK1^UAS.Tag:FLAG, Scer\GAL4^Ddc.PL is a suppressor of abnormal neuroanatomy phenotype of Pink1^RNAi.UAS.cWa, Scer\GAL4^Ddc.PL

(Wang et al., 2006)

bsk^K53R.UAS/Scer\GAL4^Ddc.PL is a suppressor of abnormal neuroanatomy phenotype of hep¹

(Cha et al., 2005)

Pi3K92E^UAS.Tag:MYC, Scer\GAL4^Ddc.PL is a suppressor of increased cell death phenotype of DJ-1α^RNAi.UAS, Scer\GAL4^Ddc.PL

(Yang et al., 2005)

Hsap\PRKN^UAS.cYa, Scer\GAL4^Ddc.PL is a suppressor of abnormal neuroanatomy phenotype of Hsap\SNCA^A30P.UAS, Scer\GAL4^Ddc.PL

(Yang et al., 2003)

Hsap\PRKN^UAS.cYa, Scer\GAL4^Ddc.PL is a suppressor of abnormal neuroanatomy phenotype of Hsap\SNCA^UAS.cFa, Scer\GAL4^Ddc.PL

(Yang et al., 2003)

Hsap\PRKN^UAS.cYa, Scer\GAL4^Ddc.PL is a suppressor of abnormal neuroanatomy phenotype of Hsap\SNCA^A53T.UAS, Scer\GAL4^Ddc.PL

(Yang et al., 2003)

Hsap\PRKN^UAS.cYa, Scer\GAL4^Ddc.PL is a suppressor of abnormal neuroanatomy phenotype of Hsap\GPR37^UAS.cYa, Scer\GAL4^Ddc.PL

(Yang et al., 2003)

Hsap\HSPA1L^UAS.cWa, Scer\GAL4^Ddc.PL is a suppressor of abnormal neuroanatomy phenotype of Hsap\SNCA^UAS.cFa, Scer\GAL4^Ddc.PL

(Auluck et al., 2002)

NOT Suppressor of

Statement

Reference

Arl8^Q75L.UAS, Scer\GAL4^Ddc.PL is a non-suppressor of short lived phenotype of Hsap\SNCA^A53T.UAS, Scer\GAL4^Ddc.PL

(Szinyákovics et al., 2023)

SERCA[+], NUCB1^NIG.32190R, Scer\GAL4^Ddc.PL, SERCA^Kum170 is a non-suppressor of abnormal flight phenotype of Itpr^wc703/Itpr^ug3

(Balasubramanian and Srinivasan, 2020)

SERCA[+], NUCB1^NIG.32190R, Scer\GAL4^Ddc.PL, SERCA^Kum170 is a non-suppressor of abnormal flight phenotype of Itpr^wc361/Itpr^ug3

(Balasubramanian and Srinivasan, 2020)

AMPKα^TD.UAS, Scer\GAL4^Ddc.PL is a non-suppressor of decreased cell number | adult stage phenotype of Scer\GAL4^Ddc.PL, srl^KK100201

(Ng et al., 2017)

AMPKα^TD.UAS/srl^KK100201, Scer\GAL4^Ddc.PL is a non-suppressor of abnormal locomotor behavior | adult stage phenotype of Hsap\LRRK2^{G2019S.UAS.Tag:MYC}, Scer\GAL4^Ddc.PL

(Ng et al., 2017)

AMPKα^TD.UAS/srl^KK100201, Scer\GAL4^Ddc.PL is a non-suppressor of decreased cell number | adult stage phenotype of Hsap\LRRK2^{G2019S.UAS.Tag:MYC}, Scer\GAL4^Ddc.PL

(Ng et al., 2017)

Hsap\RPS15^UAS.cMa, Scer\GAL4^Ddc.PL is a non-suppressor of abnormal locomotor behavior | progressive phenotype of Hsap\LRRK2^{G2019S.UAS.Tag:FLAG}, Scer\GAL4^Ddc.PL

(Martin et al., 2014)

Hsap\RPS15^UAS.cMa, Scer\GAL4^Ddc.PL is a non-suppressor of abnormal neuroanatomy | progressive phenotype of Hsap\LRRK2^{G2019S.UAS.Tag:FLAG}, Scer\GAL4^Ddc.PL

(Martin et al., 2014)

Scer\LSG1^UAS.cHa/Scer\GAL4^Ddc.PL is a non-suppressor of abnormal developmental rate | male phenotype of Ns3^G0431

(Hartl et al., 2013)

Hsap\TRAP1^UAS.cBa, Scer\GAL4^Ddc.PL is a non-suppressor of short lived phenotype of Hsap\SNCA^A53T.UAS.cKa, Scer\GAL4^Ddc.PL

(Butler et al., 2012)

sgg^UAS.cBa, Scer\GAL4^Ddc.PL is a non-suppressor of abnormal neuroanatomy phenotype of Hsap\LRRK2^{G2019S.UAS.cLa.Tag:FLAG}, Scer\GAL4^Ddc.PL

(Lin et al., 2010)

Phenotype Manifest In

Enhanced by

Statement

Reference

Hsap\LRRK2^GS.UAS.cLa, Scer\GAL4^Ddc.PL has dopaminergic PPM1 neuron | decreased number phenotype, enhanceable by Hsap\AP2M1^{TA.UAS.Tag:HA}, Scer\GAL4^Ddc.PL

(Liu et al., 2021)

Hsap\LRRK2^GS.UAS.cLa, Scer\GAL4^Ddc.PL has dopaminergic PPM2 neuron | decreased number phenotype, enhanceable by Hsap\AP2M1^{TA.UAS.Tag:HA}, Scer\GAL4^Ddc.PL

(Liu et al., 2021)

Hsap\LRRK2^UAS.cLa, Scer\GAL4^Ddc.PL has dopaminergic PPM3 neuron | decreased number phenotype, enhanceable by Hsap\AP2M1^UAS.Tag:HA, Scer\GAL4^Ddc.PL

(Liu et al., 2021)

Hsap\LRRK2^GS.UAS.cLa, Scer\GAL4^Ddc.PL has dopaminergic PPL1 neuron | decreased number phenotype, enhanceable by Hsap\AP2M1^UAS.Tag:HA, Scer\GAL4^Ddc.PL

(Liu et al., 2021)

Scer\GAL4^Ddc.PL, Septin4^UAS.cMa has dopaminergic neuron & adult brain phenotype, enhanceable by park^Δ21/park[+]

(Muñoz-Soriano and Paricio, 2007)

DJ-1α^RNAi.UAS, Scer\GAL4^Ddc.PL has dopaminergic neuron phenotype, enhanceable by Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^Ddc.PL

(Yang et al., 2005)

Hsap\GPR37^UAS.cYa, Scer\GAL4^Ddc.PL has dopaminergic neuron phenotype, enhanceable by park^RNAi.UAS, Scer\GAL4^Ddc.PL

(Yang et al., 2003)

Hsap\SNCA^UAS.cFa, Scer\GAL4^Ddc.PL has dopaminergic neuron phenotype, enhanceable by Hsc70-4^K71S.UAS, Scer\GAL4^Ddc.PL

(Auluck et al., 2002)

NOT Enhanced by

Statement

Reference

Hsap\LRRK2^GS.UAS.cLa, Scer\GAL4^Ddc.PL has dopaminergic PPM3 neuron | decreased number phenotype, non-enhanceable by Hsap\AP2M1^{TA.UAS.Tag:HA}, Scer\GAL4^Ddc.PL

(Liu et al., 2021)

Hsap\LRRK2^GS.UAS.cLa, Scer\GAL4^Ddc.PL has dopaminergic PPL1 neuron | decreased number phenotype, non-enhanceable by Hsap\AP2M1^{TA.UAS.Tag:HA}, Scer\GAL4^Ddc.PL

(Liu et al., 2021)

Hsap\LRRK2^UAS.cLa, Scer\GAL4^Ddc.PL has dopaminergic PPM3 neuron | decreased number phenotype, non-enhanceable by Hsap\AP2M1^UAS.Tag:HA, Scer\GAL4^Ddc.PL

(Liu et al., 2021)

Hsap\LRRK2^UAS.cLa, Scer\GAL4^Ddc.PL has dopaminergic PPM1 neuron | decreased number phenotype, non-enhanceable by Hsap\AP2M1^UAS.Tag:HA, Scer\GAL4^Ddc.PL

(Liu et al., 2021)

Hsap\LRRK2^UAS.cLa, Scer\GAL4^Ddc.PL has dopaminergic PPM2 neuron | decreased number phenotype, non-enhanceable by Hsap\AP2M1^UAS.Tag:HA, Scer\GAL4^Ddc.PL

(Liu et al., 2021)

Hsap\LRRK2^UAS.cLa, Scer\GAL4^Ddc.PL has dopaminergic PPM3 neuron | decreased number phenotype, non-enhanceable by Hsap\AP2M1^{TA.UAS.Tag:HA}, Scer\GAL4^Ddc.PL

(Liu et al., 2021)

Hsap\LRRK2^UAS.cLa, Scer\GAL4^Ddc.PL has dopaminergic PPM1 neuron | decreased number phenotype, non-enhanceable by Hsap\AP2M1^{TA.UAS.Tag:HA}, Scer\GAL4^Ddc.PL

(Liu et al., 2021)

Hsap\LRRK2^UAS.cLa, Scer\GAL4^Ddc.PL has dopaminergic PPM2 neuron | decreased number phenotype, non-enhanceable by Hsap\AP2M1^{TA.UAS.Tag:HA}, Scer\GAL4^Ddc.PL

(Liu et al., 2021)

Hsap\LRRK2^GS.UAS.cLa, Scer\GAL4^Ddc.PL has dopaminergic PPM1 neuron | decreased number phenotype, non-enhanceable by Hsap\AP2M1^UAS.Tag:HA, Scer\GAL4^Ddc.PL

(Liu et al., 2021)

Hsap\LRRK2^GS.UAS.cLa, Scer\GAL4^Ddc.PL has dopaminergic PPM2 neuron | decreased number phenotype, non-enhanceable by Hsap\AP2M1^UAS.Tag:HA, Scer\GAL4^Ddc.PL

(Liu et al., 2021)

Hsap\LRRK2^GS.UAS.cLa, Scer\GAL4^Ddc.PL has dopaminergic PPM3 neuron | decreased number phenotype, non-enhanceable by Hsap\AP2M1^UAS.Tag:HA, Scer\GAL4^Ddc.PL

(Liu et al., 2021)

Hsap\LRRK2^{G2019S.UAS.Tag:MYC}, Scer\GAL4^Ddc.PL has dopaminergic PPL1 neuron phenotype, non-enhanceable by AMPKα^GD736, Scer\GAL4^Ddc.PL

(Ng et al., 2012)

Hsap\LRRK2^{G2019S.UAS.cLa.Tag:FLAG}, Scer\GAL4^Ddc.PL has dendrite phenotype, non-enhanceable by sgg^UAS.cBa, Scer\GAL4^Ddc.PL

(Lin et al., 2010)

Suppressed by

Statement

Reference

Hsap\LRRK2^{G2019S.UAS.Tag:MYC}, Scer\GAL4^Ddc.PL has dopaminergic PPL1 neuron | adult stage phenotype, suppressible by AMPKα^TD.UAS, Scer\GAL4^Ddc.PL

(Ng et al., 2017)

Hsap\LRRK2^{G2019S.UAS.Tag:MYC}, Scer\GAL4^Ddc.PL has mitochondrion | adult stage phenotype, suppressible by srl^UAS.cTa, Scer\GAL4^Ddc.PL

(Ng et al., 2017)

Hsap\LRRK2^{G2019S.UAS.Tag:MYC}, Scer\GAL4^Ddc.PL has dopaminergic PPL1 neuron | adult stage phenotype, suppressible by srl^UAS.cTa, Scer\GAL4^Ddc.PL

(Ng et al., 2017)

Hsap\LRRK2^{G2019S.UAS.Tag:FLAG}, Scer\GAL4^Ddc.PL has dopaminergic neuron | progressive phenotype, suppressible by Hsap\RPS15^T136A.UAS, Scer\GAL4^Ddc.PL

(Martin et al., 2014)

Hsap\SNCA^A53T.UAS.cKa, Scer\GAL4^Ddc.PL has dopaminergic neuron | adult stage phenotype, suppressible by Hsap\TRAP1^UAS.cBa, Scer\GAL4^Ddc.PL

(Butler et al., 2012)

Hsap\LRRK2^{G2019S.UAS.Tag:MYC}, Scer\GAL4^Ddc.PL has dopaminergic neuron phenotype, suppressible by Hsap\PRKN^WT.UAS, Scer\GAL4^Ddc.PL

(Ng et al., 2012)

Hsap\LRRK2^{G2019S.UAS.Tag:MYC}, Scer\GAL4^Ddc.PL has mitochondrion phenotype, suppressible by Hsap\PRKN^WT.UAS, Scer\GAL4^Ddc.PL

(Ng et al., 2012)

Scer\GAL4^Ddc.PL, elgi^UAS.Tag:HA has dopaminergic neuron | adult stage phenotype, suppressible | partially by Hsap\PRKN^UAS.cYa, Scer\GAL4^Ddc.PL

(Tan et al., 2011)

Hsap\LRRK2^{G2019S.UAS.cLa.Tag:FLAG}, Scer\GAL4^Ddc.PL has dendrite phenotype, suppressible by sgg^A81T.UAS, Scer\GAL4^Ddc.PL

(Lin et al., 2010)

DJ-1α^RNAi.UAS, Scer\GAL4^Ddc.PL has dopaminergic neuron | adult stage | progressive phenotype, suppressible by Hsap\PARK7^UAS.cYa, Scer\GAL4^Ddc.PL

(Faust et al., 2009)

Hsap\SNCA^UAS.cFa, Scer\GAL4^Ddc.PL has dopaminergic neuron phenotype, suppressible by Hsap\UBC^UAS.Tag:HA, Scer\GAL4^Ddc.PL

(Lee et al., 2009)

Hsap\LRRK2^{G2019S.UAS.Tag:MYC}, Scer\GAL4^Ddc.PL has dopaminergic PPM2 neuron | adult stage | chemical conditional phenotype, suppressible by Hsap\PRKN^WT.UAS, Scer\GAL4^Ddc.PL

(Ng et al., 2009)

Hsap\LRRK2^{G2019S.UAS.Tag:MYC}, Scer\GAL4^Ddc.PL has dopaminergic PPM3 neuron | adult stage | chemical conditional phenotype, suppressible by Hsap\PRKN^WT.UAS, Scer\GAL4^Ddc.PL

(Ng et al., 2009)

Hsap\LRRK2^{G2019S.UAS.Tag:MYC}, Scer\GAL4^Ddc.PL has dopaminergic PPM1 neuron | adult stage | progressive phenotype, suppressible by Hsap\PRKN^WT.UAS, Scer\GAL4^Ddc.PL

(Ng et al., 2009)

Hsap\LRRK2^{G2019S.UAS.Tag:MYC}, Scer\GAL4^Ddc.PL has dopaminergic PPM3 neuron | adult stage | progressive phenotype, suppressible by Hsap\PRKN^WT.UAS, Scer\GAL4^Ddc.PL

(Ng et al., 2009)

Scer\GAL4^Ddc.PL, Septin4^UAS.cMa has dopaminergic neuron & adult brain phenotype, suppressible | partially by park^UAS.cMa/Scer\GAL4^Ddc.PL

(Muñoz-Soriano and Paricio, 2007)

Pink1^RNAi.UAS.cWa, Scer\GAL4^Ddc.PL has dopamine neuron & adult brain phenotype, suppressible by Hsap\PINK1^UAS.Tag:FLAG, Scer\GAL4^Ddc.PL

(Wang et al., 2006)

DJ-1α^RNAi.UAS, Scer\GAL4^Ddc.PL has dopaminergic neuron phenotype, suppressible by Pi3K92E^UAS.Tag:MYC, Scer\GAL4^Ddc.PL

(Yang et al., 2005)

Hsap\SNCA^A30P.UAS, Scer\GAL4^Ddc.PL has dopaminergic neuron phenotype, suppressible by Hsap\PRKN^UAS.cYa, Scer\GAL4^Ddc.PL

(Yang et al., 2003)

Hsap\SNCA^UAS.cFa, Scer\GAL4^Ddc.PL has dopaminergic neuron phenotype, suppressible by Hsap\PRKN^UAS.cYa, Scer\GAL4^Ddc.PL

(Yang et al., 2003)

Hsap\SNCA^A53T.UAS, Scer\GAL4^Ddc.PL has dopaminergic neuron phenotype, suppressible by Hsap\PRKN^UAS.cYa, Scer\GAL4^Ddc.PL

(Yang et al., 2003)

Hsap\GPR37^UAS.cYa, Scer\GAL4^Ddc.PL has dopaminergic neuron phenotype, suppressible by Hsap\PRKN^UAS.cYa, Scer\GAL4^Ddc.PL

(Yang et al., 2003)

Hsap\SNCA^UAS.cFa, Scer\GAL4^Ddc.PL has dopaminergic neuron phenotype, suppressible by Hsap\HSPA1L^UAS.cWa, Scer\GAL4^Ddc.PL

(Auluck et al., 2002)

NOT suppressed by

Statement

Reference

Scer\GAL4^Ddc.PL, srl^KK100201 has dopaminergic PPL1 neuron | adult stage phenotype, non-suppressible by AMPKα^TD.UAS, Scer\GAL4^Ddc.PL

(Ng et al., 2017)

Hsap\LRRK2^{G2019S.UAS.Tag:MYC}, Scer\GAL4^Ddc.PL has dopaminergic PPL1 neuron | adult stage phenotype, non-suppressible by AMPKα^TD.UAS/srl^KK100201, Scer\GAL4^Ddc.PL

(Ng et al., 2017)

Hsap\LRRK2^{G2019S.UAS.Tag:FLAG}, Scer\GAL4^Ddc.PL has dopaminergic neuron | progressive phenotype, non-suppressible by Hsap\RPS15^UAS.cMa, Scer\GAL4^Ddc.PL

(Martin et al., 2014)

Hsap\LRRK2^{G2019S.UAS.cLa.Tag:FLAG}, Scer\GAL4^Ddc.PL has dendrite phenotype, non-suppressible by sgg^UAS.cBa, Scer\GAL4^Ddc.PL

(Lin et al., 2010)

Enhancer of

Statement

Reference

Hsap\AP2M1^{TA.UAS.Tag:HA}, Scer\GAL4^Ddc.PL is an enhancer of dopaminergic PPM1 neuron | decreased number phenotype of Hsap\LRRK2^GS.UAS.cLa, Scer\GAL4^Ddc.PL

(Liu et al., 2021)

Hsap\AP2M1^{TA.UAS.Tag:HA}, Scer\GAL4^Ddc.PL is an enhancer of dopaminergic PPM2 neuron | decreased number phenotype of Hsap\LRRK2^GS.UAS.cLa, Scer\GAL4^Ddc.PL

(Liu et al., 2021)

Hsap\AP2M1^UAS.Tag:HA, Scer\GAL4^Ddc.PL is an enhancer of dopaminergic PPM3 neuron | decreased number phenotype of Hsap\LRRK2^UAS.cLa, Scer\GAL4^Ddc.PL

(Liu et al., 2021)

Hsap\AP2M1^UAS.Tag:HA, Scer\GAL4^Ddc.PL is an enhancer of dopaminergic PPL1 neuron | decreased number phenotype of Hsap\LRRK2^GS.UAS.cLa, Scer\GAL4^Ddc.PL

(Liu et al., 2021)

Buffy^RNAi.UAS/Scer\GAL4^Ddc.PL is an enhancer of eye phenotype of Hsap\SNCA^UAS.cFa, Scer\GAL4^GMR.PU

(M'Angale and Staveley, 2016)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^Ddc.PL is an enhancer of dopaminergic neuron phenotype of DJ-1α^RNAi.UAS, Scer\GAL4^Ddc.PL

(Yang et al., 2005)

park^RNAi.UAS, Scer\GAL4^Ddc.PL is an enhancer of dopaminergic neuron phenotype of Hsap\GPR37^UAS.cYa, Scer\GAL4^Ddc.PL

(Yang et al., 2003)

Hsc70-4^K71S.UAS, Scer\GAL4^Ddc.PL is an enhancer of dopaminergic neuron phenotype of Hsap\SNCA^UAS.cFa, Scer\GAL4^Ddc.PL

(Auluck et al., 2002)

NOT Enhancer of

Statement

Reference

Hsap\AP2M1^{TA.UAS.Tag:HA}, Scer\GAL4^Ddc.PL is a non-enhancer of dopaminergic PPM3 neuron | decreased number phenotype of Hsap\LRRK2^GS.UAS.cLa, Scer\GAL4^Ddc.PL

(Liu et al., 2021)

Hsap\AP2M1^{TA.UAS.Tag:HA}, Scer\GAL4^Ddc.PL is a non-enhancer of dopaminergic PPL1 neuron | decreased number phenotype of Hsap\LRRK2^GS.UAS.cLa, Scer\GAL4^Ddc.PL

(Liu et al., 2021)

Hsap\AP2M1^UAS.Tag:HA, Scer\GAL4^Ddc.PL is a non-enhancer of dopaminergic PPM3 neuron | decreased number phenotype of Hsap\LRRK2^UAS.cLa, Scer\GAL4^Ddc.PL

(Liu et al., 2021)

Hsap\AP2M1^UAS.Tag:HA, Scer\GAL4^Ddc.PL is a non-enhancer of dopaminergic PPM1 neuron | decreased number phenotype of Hsap\LRRK2^UAS.cLa, Scer\GAL4^Ddc.PL

(Liu et al., 2021)

Hsap\AP2M1^UAS.Tag:HA, Scer\GAL4^Ddc.PL is a non-enhancer of dopaminergic PPM2 neuron | decreased number phenotype of Hsap\LRRK2^UAS.cLa, Scer\GAL4^Ddc.PL

(Liu et al., 2021)

Hsap\AP2M1^{TA.UAS.Tag:HA}, Scer\GAL4^Ddc.PL is a non-enhancer of dopaminergic PPM3 neuron | decreased number phenotype of Hsap\LRRK2^UAS.cLa, Scer\GAL4^Ddc.PL

(Liu et al., 2021)

Hsap\AP2M1^{TA.UAS.Tag:HA}, Scer\GAL4^Ddc.PL is a non-enhancer of dopaminergic PPM1 neuron | decreased number phenotype of Hsap\LRRK2^UAS.cLa, Scer\GAL4^Ddc.PL

(Liu et al., 2021)

Hsap\AP2M1^{TA.UAS.Tag:HA}, Scer\GAL4^Ddc.PL is a non-enhancer of dopaminergic PPM2 neuron | decreased number phenotype of Hsap\LRRK2^UAS.cLa, Scer\GAL4^Ddc.PL

(Liu et al., 2021)

Hsap\AP2M1^UAS.Tag:HA, Scer\GAL4^Ddc.PL is a non-enhancer of dopaminergic PPM1 neuron | decreased number phenotype of Hsap\LRRK2^GS.UAS.cLa, Scer\GAL4^Ddc.PL

(Liu et al., 2021)

Hsap\AP2M1^UAS.Tag:HA, Scer\GAL4^Ddc.PL is a non-enhancer of dopaminergic PPM2 neuron | decreased number phenotype of Hsap\LRRK2^GS.UAS.cLa, Scer\GAL4^Ddc.PL

(Liu et al., 2021)

Hsap\AP2M1^UAS.Tag:HA, Scer\GAL4^Ddc.PL is a non-enhancer of dopaminergic PPM3 neuron | decreased number phenotype of Hsap\LRRK2^GS.UAS.cLa, Scer\GAL4^Ddc.PL

(Liu et al., 2021)

AMPKα^GD736, Scer\GAL4^Ddc.PL is a non-enhancer of dopaminergic PPL1 neuron phenotype of Hsap\LRRK2^{G2019S.UAS.Tag:MYC}, Scer\GAL4^Ddc.PL

(Ng et al., 2012)

sgg^UAS.cBa, Scer\GAL4^Ddc.PL is a non-enhancer of dendrite phenotype of Hsap\LRRK2^{G2019S.UAS.cLa.Tag:FLAG}, Scer\GAL4^Ddc.PL

(Lin et al., 2010)

Hsap\PRKN^R275W.UAS/Scer\GAL4^Ddc.PL is a non-enhancer of dopaminergic PPL1 neuron | adult stage phenotype of park¹

(Wang et al., 2007)

Hsap\PRKN^R275W.UAS/Scer\GAL4^Ddc.PL is a non-enhancer of adult dopaminergic PAM neuron | adult stage phenotype of park¹

(Wang et al., 2007)

Suppressor of

Statement

Reference

NUCB1^NIG.32190R/Scer\GAL4^Ddc.PL is a suppressor of wing phenotype of Itpr^wc703/Itpr^ug3

(Balasubramanian and Srinivasan, 2020)

NUCB1^NIG.32190R/Scer\GAL4^Ddc.PL is a suppressor of wing phenotype of Itpr^wc361/Itpr^ug3

(Balasubramanian and Srinivasan, 2020)

AMPKα^TD.UAS, Scer\GAL4^Ddc.PL is a suppressor of dopaminergic PPL1 neuron | adult stage phenotype of Hsap\LRRK2^{G2019S.UAS.Tag:MYC}, Scer\GAL4^Ddc.PL

(Ng et al., 2017)

srl^UAS.cTa, Scer\GAL4^Ddc.PL is a suppressor of mitochondrion | adult stage phenotype of Hsap\LRRK2^{G2019S.UAS.Tag:MYC}, Scer\GAL4^Ddc.PL

(Ng et al., 2017)

srl^UAS.cTa, Scer\GAL4^Ddc.PL is a suppressor of dopaminergic PPL1 neuron | adult stage phenotype of Hsap\LRRK2^{G2019S.UAS.Tag:MYC}, Scer\GAL4^Ddc.PL

(Ng et al., 2017)

Buffy^UAS.cQa/Scer\GAL4^Ddc.PL is a suppressor of eye phenotype of Hsap\SNCA^UAS.cFa, Scer\GAL4^GMR.PU

(M'Angale and Staveley, 2016)

Buffy^UAS.cQa/Scer\GAL4^Ddc.PL is a suppressor of eye phenotype of Lfg^KK104535, Scer\GAL4^GMR.PF

(M'Angale and Staveley, 2016)

Buffy^UAS.cQa/Scer\GAL4^Ddc.PL is a suppressor of eye phenotype of Lfg^HMS00225, Scer\GAL4^GMR.PF

(M'Angale and Staveley, 2016)

Hsap\RPS15^T136A.UAS, Scer\GAL4^Ddc.PL is a suppressor of dopaminergic neuron | progressive phenotype of Hsap\LRRK2^{G2019S.UAS.Tag:FLAG}, Scer\GAL4^Ddc.PL

(Martin et al., 2014)

Hsap\TRAP1^UAS.cBa, Scer\GAL4^Ddc.PL is a suppressor of dopaminergic neuron | adult stage phenotype of Hsap\SNCA^A53T.UAS.cKa, Scer\GAL4^Ddc.PL

(Butler et al., 2012)

Hsap\PRKN^WT.UAS, Scer\GAL4^Ddc.PL is a suppressor of dopaminergic neuron phenotype of Hsap\LRRK2^{G2019S.UAS.Tag:MYC}, Scer\GAL4^Ddc.PL

(Ng et al., 2012)

Hsap\PRKN^WT.UAS, Scer\GAL4^Ddc.PL is a suppressor of mitochondrion phenotype of Hsap\LRRK2^{G2019S.UAS.Tag:MYC}, Scer\GAL4^Ddc.PL

(Ng et al., 2012)

Hsap\PRKN^UAS.cYa, Scer\GAL4^Ddc.PL is a suppressor | partially of dopaminergic neuron | adult stage phenotype of Scer\GAL4^Ddc.PL, elgi^UAS.Tag:HA

(Tan et al., 2011)

Stim^UAS.cAa/Scer\GAL4^Ddc.PL is a suppressor of wing phenotype of Itpr^ug3/Itpr^ka1091

(Agrawal et al., 2010)

sgg^A81T.UAS, Scer\GAL4^Ddc.PL is a suppressor of dendrite phenotype of Hsap\LRRK2^{G2019S.UAS.cLa.Tag:FLAG}, Scer\GAL4^Ddc.PL

(Lin et al., 2010)

Hsap\PARK7^UAS.cYa, Scer\GAL4^Ddc.PL is a suppressor of dopaminergic neuron | adult stage | progressive phenotype of DJ-1α^RNAi.UAS, Scer\GAL4^Ddc.PL

(Faust et al., 2009)

Hsap\UBC^UAS.Tag:HA, Scer\GAL4^Ddc.PL is a suppressor of dopaminergic neuron phenotype of Hsap\SNCA^UAS.cFa, Scer\GAL4^Ddc.PL

(Lee et al., 2009)

Hsap\PRKN^WT.UAS, Scer\GAL4^Ddc.PL is a suppressor of dopaminergic PPM2 neuron | adult stage | chemical conditional phenotype of Hsap\LRRK2^{G2019S.UAS.Tag:MYC}, Scer\GAL4^Ddc.PL

(Ng et al., 2009)

Hsap\PRKN^WT.UAS, Scer\GAL4^Ddc.PL is a suppressor of dopaminergic PPM3 neuron | adult stage | chemical conditional phenotype of Hsap\LRRK2^{G2019S.UAS.Tag:MYC}, Scer\GAL4^Ddc.PL

(Ng et al., 2009)

Hsap\PRKN^WT.UAS, Scer\GAL4^Ddc.PL is a suppressor of dopaminergic PPM1 neuron | adult stage | progressive phenotype of Hsap\LRRK2^{G2019S.UAS.Tag:MYC}, Scer\GAL4^Ddc.PL

(Ng et al., 2009)

Hsap\PRKN^WT.UAS, Scer\GAL4^Ddc.PL is a suppressor of dopaminergic PPM3 neuron | adult stage | progressive phenotype of Hsap\LRRK2^{G2019S.UAS.Tag:MYC}, Scer\GAL4^Ddc.PL

(Ng et al., 2009)

park^UAS.cMa/Scer\GAL4^Ddc.PL is a suppressor | partially of dopaminergic neuron & adult brain phenotype of Scer\GAL4^Ddc.PL, Septin4^UAS.cMa

(Muñoz-Soriano and Paricio, 2007)

Hsap\PRKN^WT.UAS/Scer\GAL4^Ddc.PL is a suppressor of dopaminergic PPL1 neuron | adult stage phenotype of park¹

(Wang et al., 2007)

Hsap\PRKN^WT.UAS/Scer\GAL4^Ddc.PL is a suppressor of adult dopaminergic PAM neuron | adult stage phenotype of park¹

(Wang et al., 2007)

Gαq^UAS.cRa/Scer\GAL4^Ddc.PL is a suppressor | partially of wing phenotype of Gα49B[+]/Gαq^221c, Itpr^wc703/Itpr^wc361

(Banerjee et al., 2006)

Hsap\PINK1^UAS.Tag:FLAG, Scer\GAL4^Ddc.PL is a suppressor of dopamine neuron & adult brain phenotype of Pink1^RNAi.UAS.cWa, Scer\GAL4^Ddc.PL

(Wang et al., 2006)

bsk^K53R.UAS/Scer\GAL4^Ddc.PL is a suppressor of insulin secreting cell of pars intercerebralis phenotype of hep¹

(Cha et al., 2005)

Pi3K92E^UAS.Tag:MYC, Scer\GAL4^Ddc.PL is a suppressor of dopaminergic neuron phenotype of DJ-1α^RNAi.UAS, Scer\GAL4^Ddc.PL

(Yang et al., 2005)

Hsap\PRKN^UAS.cYa, Scer\GAL4^Ddc.PL is a suppressor of dopaminergic neuron phenotype of Hsap\SNCA^A30P.UAS, Scer\GAL4^Ddc.PL

(Yang et al., 2003)

Hsap\PRKN^UAS.cYa, Scer\GAL4^Ddc.PL is a suppressor of dopaminergic neuron phenotype of Hsap\SNCA^UAS.cFa, Scer\GAL4^Ddc.PL

(Yang et al., 2003)

Hsap\PRKN^UAS.cYa, Scer\GAL4^Ddc.PL is a suppressor of dopaminergic neuron phenotype of Hsap\SNCA^A53T.UAS, Scer\GAL4^Ddc.PL

(Yang et al., 2003)

Hsap\PRKN^UAS.cYa, Scer\GAL4^Ddc.PL is a suppressor of dopaminergic neuron phenotype of Hsap\GPR37^UAS.cYa, Scer\GAL4^Ddc.PL

(Yang et al., 2003)

Hsap\HSPA1L^UAS.cWa, Scer\GAL4^Ddc.PL is a suppressor of dopaminergic neuron phenotype of Hsap\SNCA^UAS.cFa, Scer\GAL4^Ddc.PL

(Auluck et al., 2002)

NOT Suppressor of

Statement

Reference

AMPKα^TD.UAS, Scer\GAL4^Ddc.PL is a non-suppressor of dopaminergic PPL1 neuron | adult stage phenotype of Scer\GAL4^Ddc.PL, srl^KK100201

(Ng et al., 2017)

AMPKα^TD.UAS/srl^KK100201, Scer\GAL4^Ddc.PL is a non-suppressor of dopaminergic PPL1 neuron | adult stage phenotype of Hsap\LRRK2^{G2019S.UAS.Tag:MYC}, Scer\GAL4^Ddc.PL

(Ng et al., 2017)

Hsap\RPS15^UAS.cMa, Scer\GAL4^Ddc.PL is a non-suppressor of dopaminergic neuron | progressive phenotype of Hsap\LRRK2^{G2019S.UAS.Tag:FLAG}, Scer\GAL4^Ddc.PL

(Martin et al., 2014)

sgg^UAS.cBa, Scer\GAL4^Ddc.PL is a non-suppressor of dendrite phenotype of Hsap\LRRK2^{G2019S.UAS.cLa.Tag:FLAG}, Scer\GAL4^Ddc.PL

(Lin et al., 2010)

Hsap\PRKN^R275W.UAS/Scer\GAL4^Ddc.PL is a non-suppressor of dopaminergic PPL1 neuron | adult stage phenotype of park¹

(Wang et al., 2007)

Hsap\PRKN^R275W.UAS/Scer\GAL4^Ddc.PL is a non-suppressor of adult dopaminergic PAM neuron | adult stage phenotype of park¹

(Wang et al., 2007)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Rescues

hig^UAS.GFP/Scer\GAL4^Ddc.PL rescues hig^dd37

(Nakayama et al., 2014)

Scer\GAL4^ple.PF, ple^UAS.cFa, Scer\GAL4^Ddc.PL rescues ple²

(Riemensperger et al., 2011)

Scer\GAL4^ple.PF, ple^FS.UAS, Scer\GAL4^Ddc.PL rescues ple²

(Riemensperger et al., 2011)

park^UAS.Tag:MYC/Scer\GAL4^Ddc.PL rescues park¹

(Cha et al., 2005)

Scer\GAL4^Ddc.PL/Itpr^UAS.cVa rescues Itpr^ug3/Itpr^ka1091

(Banerjee et al., 2004)

Scer\GAL4^Ddc.PL/Itpr^UAS.cVa rescues Itpr^wc703/Itpr^ug3

(Banerjee et al., 2004)

Partially rescues

Pngl^UASp.cFa/Scer\GAL4^Ddc.PL partially rescues Pngl^PL

(Hope et al., 2022)

mbt^UAS.cMa/Scer\GAL4^Ddc.PL partially rescues mbt^P1

(Pütz et al., 2021)

Scer\GAL4^Ddc.PL/Ns3^UAS.Venus partially rescues Ns3^{K350N.UAS.Venus}

(Hartl et al., 2013)

Scer\GAL4^Ddc.PL/Itpr^UAS.cVa partially rescues Itpr^sv35/Itpr^ug3

(Agrawal et al., 2009)

Scer\GAL4^Ilp2.PR, Scer\GAL4^Ddc.PL, Itpr^UAS.cVa partially rescues Itpr^sv35/Itpr^ug3

(Agrawal et al., 2009)

fbl^L.UAS/Scer\GAL4^Ddc.PL partially rescues fbl¹

(Wu et al., 2009)

atl^UAS.cLa/Scer\GAL4^Ddc.PL partially rescues atl¹

(Lee et al., 2008)

Scer\GAL4^Ddc.PL/Itpr^UAS.cVa partially rescues Itpr^ka901/Itpr^ug3

(Joshi et al., 2004)

Fails to rescue

Pngl^C303A.UASp/Scer\GAL4^Ddc.PL fails to rescue Pngl^PL

(Hope et al., 2022)

Nf1^UAS.cdNa/Scer\GAL4^Ddc.PL fails to rescue Nf1^P2/Nf1^P1

(Bai et al., 2018)

Ns3^{K350N.UAS.Venus}/Scer\GAL4^Ddc.PL fails to rescue Ns3^G0431

(Hartl et al., 2013)

tutl^RE40452.UAS/Scer\GAL4^Ddc.PL fails to rescue tutl²³

(Zhou et al., 2012)

Adar^3.4.S.UAS/Scer\GAL4^Ddc.PL fails to rescue Adar^5G1

(Keegan et al., 2011)

Scer\GAL4^ple.PF, ple^FStrunc.UAS, Scer\GAL4^Ddc.PL fails to rescue ple²

(Riemensperger et al., 2011)

Nf1^UAS.cWa/Scer\GAL4^Ddc.PL fails to rescue Nf1^unspecified

(Walker et al., 2006)

sbb^UAS.cYa/Scer\GAL4^Ddc.PL fails to rescue sbb⁰³⁴³²

(Suster et al., 2004)

Tbh^UAS.cMa/Scer\GAL4^Ddc.PL fails to rescue Tbh^nM18

(Monastirioti, 2003)

Comments

Images (0)

Mutant

Wild-type

Stocks (2)

Bloomington

7010

w¹¹¹⁸; P{Ddc-GAL4.L}4.3D

7009

w¹¹¹⁸; P{Ddc-GAL4.L}Lmpt^4.36

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

Scer\GAL4^Ddc.PL

ddc-GAL4

(Sykes et al., 2004)

Name Synonyms

Secondary FlyBase IDs

References (194)

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