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General Information
Symbol
Dmel\Ptp69DD1689
Species
D. melanogaster
Name
FlyBase ID
FBal0104731
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Nature of the Allele
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
point mutation
Nucleotide change:

G12736121A

Reported nucleotide change:

G?A

Amino acid change:

W54term | Ptp69D-PA; W54term | Ptp69D-PB

Reported amino acid change:

W54term

Comment:

G to A nucleotide change at the second or third position of the Trp codon leads to a nonsense mutation (exact site of mutation unspecified).

Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference

Amino acid replacement: W54term.

Mutation is predicted to result in a protein truncated in the first Ig domain (before the catalytic domain).

Nucleotide substitution: G?A.

Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In

photoreceptor cell & axon | somatic clone

photoreceptor cell R7 & axon | somatic clone

Detailed Description
Statement
Reference

At 25oC, the survival rates of homozygotes are: adult survival - 0%, eclosion - 5%, pupation 26%.

Mutant R7 axons show targeting defects.

Photoreceptor fates are correctly specified, but their axons project abnormally into the optic lobes in homozygous clones in the eye.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Suppressed by
Statement
Reference

Ptp69DD1689 has photoreceptor cell R7 & axon | somatic clone phenotype, suppressible by Lar::Ptp69DLP.GMR.Tag:SS(wg),Tag:HA

Ptp69DD1689 has photoreceptor cell R7 & axon | somatic clone phenotype, suppressible by Lar::Ptp69DPL.GMR.Tag:SS(wg),Tag:HA

Ptp69DD1689 has photoreceptor cell R7 & axon | somatic clone phenotype, suppressible by LarGMR.Tag:SS(wg),Tag:HA

Additional Comments
Genetic Interactions
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (4)
Reported As
Symbol Synonym
Name Synonyms
Secondary FlyBase IDs
    References (5)