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General Information
Symbol
Dmel\Dcp-1ΔN.GMR
Species
D. melanogaster
Name
FlyBase ID
FBal0105227
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
GMR-ΔN-dcp-1
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference

A truncated Dcp-1, missing the N-terminal prodomain, is driven by GMR sequences.

Allele components
Product class / Tool use(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Dcp-1DeltaN.GMR eyes show complete loss of ommatidial integrity. 52% of Dcp-1DeltaN.GMR differentiated pupae die.

Dcp-1ΔN.GMR flies have a "spotted" eye phenotype.

Dcp-1ΔN.GMR flies show a small and rough eye phenotype with pigment cell death. When two copies of P{GMR-ΔN-Dcp-1} are present the phenotype becomes stronger. The combination of Dcp-1ΔN.GMR and Dcp-1fl.GMR show an additive effect on the eye phenotype.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
NOT Enhanced by
Statement
Reference

Dcp-1ΔN.GMR has phenotype, non-enhanceable by DriceΔN.GMR

Dcp-1ΔN.GMR has phenotype, non-enhanceable by Dricefl.GMR

Suppressed by
NOT suppressed by
Statement
Reference

Dcp-1ΔN.GMR has eye phenotype, non-suppressible by Drice17/Drice17

NOT Enhancer of
Statement
Reference

Dcp-1ΔN.GMR is a non-enhancer of phenotype of DriceΔN.GMR

Dcp-1ΔN.GMR is a non-enhancer of phenotype of Dricefl.GMR

Additional Comments
Genetic Interactions
Statement
Reference

Scer\GAL4GMR.PF-mediated expression of P{Sym-UAS-Hsrω} nearly completely restores ommatidial integrity and eye pigmentation of Dcp-1[DeltaN.GMR] eyes. Pupal lethality is also suppressed.

The "spotted" eye phenotype caused by Dcp-1ΔN.GMR is not suppressed by homozygosity for Ice17.

The rough eye phenotype is suppressed by the addition of BacA\p35GMR.PH. The addition of Dcp-1ΔN.GMR to Icefl.GMR or IceΔN.GMR flies has no effect on eye morphology.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments

The eye phenotype observed in Dcp-1ΔN.GMR animals is rescued by expression of Dcp-1dsRNA.Scer\UAS.cLa under the control of Scer\GAL4GMR.PF.

Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (1)
Reported As
Symbol Synonym
Dcp-1ΔN.GMR
Name Synonyms
Secondary FlyBase IDs
    References (5)