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General Information
Symbol
Dmel\sisA3
Species
D. melanogaster
Name
FlyBase ID
FBal0117359
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
complex substitution
Comment:

The sisA3 allele is complex, consisting of a base substitution, an 8-bp frameshifting deletion, and a single-base deletion that restores the normal reading frame. 11 amino acids are replaced with 8 novel amino acids.

Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference

A base substitution, an 8bp frameshifting deletion and a single base deletion that restores the normal reading frame. The alteration replaces 11 amino acids with 8 novel residues prior to the restoration of the normal reading frame. The mutation is in an evolutionarily conserved N-terminal extension of the basic DNA-binding domain.

Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Male adult escapers are occasionally seen. These males are fertile and have normal morphology.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Fails to complement
Rescued by
Not rescued by
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (1)
Reported As
Symbol Synonym
sisA3
Name Synonyms
Secondary FlyBase IDs
    References (1)