FlyBase Allele Report: Dmel\sbb[UAS.cYa]

General Information

Symbol

Dmel\sbb^UAS.cYa

Species

D. melanogaster

Name

Saccharomyces cerevisiae UAS construct a of Yang

FlyBase ID

FBal0117366

Feature type

allele

Associated gene

Dmel\sbb

Associated Insertion(s)

Carried in Construct

P{UAS-sbb.Y}

Key Links

Transgenic product class

cDNA

(Yang et al., 2000)

wild_type

(Yang et al., 2000)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

cDNA

(Yang et al., 2000)

wild_type

(Yang et al., 2000)

Mutagen

in vitro construct

(Yang et al., 2000)

Progenitor genotype

Carried in construct

P{UAS-sbb.Y}

Cytology

Description

UASt regulatory sequences drive expression of the sbb EST LD13770.

(Yang et al., 2000)

Allele components

Component

Use(s)

Regulatory region(s)

UASt

binary expression system - regulatory region

Encoded product / tool

sbb

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

haltere disc, with Scer\GAL4^Tub.PU, Scer\GAL4^vg.int2.1

(Crickmore and Mann, 2006)

Detailed Description

Statement

Reference

Expression of sbb^Scer\UAS.cYa under the control of Scer\GAL4^tub and Scer\GAL4^vg.int2.1 results in a larger appendage-forming domain within the haltere disc.

(Crickmore and Mann, 2006)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Rescues

Scer\GAL4^{elav.Switch.PO}/sbb^UAS.cYa rescues sbb⁰³⁴³²

(Suster et al., 2004)

Scer\GAL4^elav-C155/sbb^UAS.cYa rescues sbb⁰³⁴³²

(Suster et al., 2004)

sbb^UAS.cYa/Scer\GAL4^ChAT.7.4 rescues sbb⁰³⁴³²

(Suster et al., 2004)

Partially rescues

Scer\GAL4^elav-C155/sbb^UAS.cYa partially rescues sbb⁰³⁴³²

(Yang et al., 2000)

Fails to rescue

sbb^UAS.cYa/Scer\GAL4^Mz1060 fails to rescue sbb⁰³⁴³²

(Suster et al., 2004)

sbb^UAS.cYa/Scer\GAL4^{l(3)31-1-31-1} fails to rescue sbb⁰³⁴³²

(Suster et al., 2004)

sbb^UAS.cYa/Scer\GAL4^tsh-MD741 fails to rescue sbb⁰³⁴³²

(Suster et al., 2004)

sbb^UAS.cYa/Scer\GAL4^12.1 fails to rescue sbb⁰³⁴³²

(Suster et al., 2004)

Scer\GAL4^109(2)80/sbb^UAS.cYa fails to rescue sbb⁰³⁴³²

(Suster et al., 2004)

sbb^UAS.cYa/Scer\GAL4^152.1 fails to rescue sbb⁰³⁴³²

(Suster et al., 2004)

sbb^UAS.cYa/Scer\GAL4^ftz.ng fails to rescue sbb⁰³⁴³²

(Suster et al., 2004)

sbb^UAS.cYa/Scer\GAL4^Toll-6-D42 fails to rescue sbb⁰³⁴³²

(Suster et al., 2004)

sbb^UAS.cYa/Scer\GAL4^RapGAP1-OK6 fails to rescue sbb⁰³⁴³²

(Suster et al., 2004)

sbb^UAS.cYa/Scer\GAL4^Ddc.PL fails to rescue sbb⁰³⁴³²

(Suster et al., 2004)

Scer\GAL4^dimm-929/sbb^UAS.cYa fails to rescue sbb⁰³⁴³²

(Suster et al., 2004)

sbb^UAS.cYa/Scer\GAL4^386Y fails to rescue sbb⁰³⁴³²

(Suster et al., 2004)

sbb^UAS.cYa/Scer\GAL4^Kdm2-36Y fails to rescue sbb⁰³⁴³²

(Suster et al., 2004)

sbb^UAS.cYa/Scer\GAL4^Feb296 fails to rescue sbb⁰³⁴³²

(Suster et al., 2004)

sbb^UAS.cYa/Scer\GAL4^Kurs21 fails to rescue sbb⁰³⁴³²

(Suster et al., 2004)

Scer\GAL4^Mai53/sbb^UAS.cYa fails to rescue sbb⁰³⁴³²

(Suster et al., 2004)

Scer\GAL4^{CenB1A-Mai301}/sbb^UAS.cYa fails to rescue sbb⁰³⁴³²

(Suster et al., 2004)

sbb^UAS.cYa/Scer\GAL4^repo.PU fails to rescue sbb⁰³⁴³²

(Suster et al., 2004)

sbb^UAS.cYa/Scer\GAL4^Mz840 fails to rescue sbb⁰³⁴³²

(Suster et al., 2004)

sbb^UAS.cYa/Scer\GAL4^how-24B fails to rescue sbb⁰³⁴³²

(Suster et al., 2004)

sbb^UAS.cYa/Scer\GAL4^nrv1.PS fails to rescue sbb⁰³⁴³²

(Suster et al., 2004)

sbb^UAS.cYa/Scer\GAL4^Mhc.PW fails to rescue sbb⁰³⁴³²

(Suster et al., 2004)

sbb^UAS.cYa/Scer\GAL4^hh-Gal4 fails to rescue sbb⁰³⁴³²

(Suster et al., 2004)

Comments

Conditional expression of sbb^UAS.cYa under the combined control of Scer\GAL4^{elav.Switch.PO} and RU486 feeding, rescues the turning behavior defects of third instar larvae if feeding-induced from hatching upto 41h post hatching onwards, but not if feeding-induced from 54h post hatching onwards.

(Suster et al., 2004)

60% of the expected number of sbb⁰³⁴³² animals rescued by expression of sbb^Scer\UAS.cYa under the control of Scer\GAL4^elav-C155 emerge as fertile adults. The sbb⁰³⁴³² wing vein phenotype is not restored to normal in these flies. Expression of sbb^Scer\UAS.cYa under the control of Scer\GAL4^elav-C155 rescues the "scribbler" locomotor behaviour of sbb⁰³⁴³² larvae.

(Yang et al., 2000)

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

sbb^Scer\UAS.cYa

sbb^UAS.cYa

Name Synonyms

Saccharomyces cerevisiae UAS construct a of Yang

(Yang et al., 2000)

Secondary FlyBase IDs

References (3)

Report Sections

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