FlyBase Allele Report: Dmel\capt[UAS.cBa]

General Information

Symbol

Dmel\capt^UAS.cBa

Species

D. melanogaster

Name

Saccharomyces cerevisiae UAS construct a of Benlali

FlyBase ID

FBal0117576

Feature type

allele

Associated gene

Dmel\capt

Associated Insertion(s)

Carried in Construct

P{UAS-capt.B}

Key Links

Allele class

Mutagen

in vitro construct - regulatory fusion

Nature of the Allele

Allele class

Mutagen

in vitro construct - regulatory fusion

(Benlali et al., 2000)

Mutations Mapped to the Genome

Type

Location

Additional Notes

References

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Progenitor genotype

Carried in construct

P{UAS-capt.B}

Cytology

Nature of the lesion

Statement

Reference

A full length capt cDNA is expressed under the control of UASt regulatory sequences.

(Benlali et al., 2000)

Allele components

Product class / Tool use(s)

Regulatory region(s)

UASt

binary expression system - regulatory region

Encoded product / tool

capt

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal neuroanatomy, with Scer\GAL4^109(2)80

(Medina et al., 2008)

Phenotype Manifest In

filopodium, with Scer\GAL4^109(2)80

(Medina et al., 2008)

Detailed Description

Statement

Reference

Expression of capt^Scer\UAS.cBa under the control of Scer\GAL4^109(2)80 suppresses formation of F-actin rich dendritic filopodia in the peripheral nervous system.

(Medina et al., 2008)

Expression of capt^Scer\UAS.cBa under the control of Scer\GAL4^ey.PH has no effect on photoreceptor differentiation.

(Benlali et al., 2000)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressor of

Statement

Reference

Scer\GAL4^109(2)80/capt^UAS.cBa is a suppressor of abnormal neuroanatomy phenotype of Scer\GAL4^109(2)80, tsr^UAS.cNa

(Medina et al., 2008)

Phenotype Manifest In

Suppressor of

Statement

Reference

Scer\GAL4^109(2)80/capt^UAS.cBa is a suppressor of dendrite phenotype of Scer\GAL4^109(2)80, tsr^UAS.cNa

(Medina et al., 2008)

Additional Comments

Genetic Interactions

Statement

Reference

No rod-like structures of Act5C^{Scer\UAS.T:Avic\GFP} accumulation are formed in the dendrites of animals expressing tsr^Scer\UAS.cNa under the control of Scer\GAL4^109(2)80 is they are also co-expressing capt^Scer\UAS.cBa.

(Medina et al., 2008)

Expression of capt^Scer\UAS.cBa under the control of Scer\GAL4^elav.PLu completely rescues the midline crossing defects seen in capt^E636 Abl² double heterozygotes.

(Wills et al., 2002)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Partially rescues

Scer\GAL4^da.G32/capt^UAS.cBa partially rescues capt^E636/capt^E593

(Benlali et al., 2000)

Comments

Expression of capt^Scer\UAS.cBa under the control of Scer\GAL4^da.G32 rescues capt^E593/capt^E636 animals to viability, although the rescued adults sometimes show wing or eye defects.

(Benlali et al., 2000)

Images (0)

Mutant

Wild-type

Stocks (2)

5943

108495

Notes on Origin