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General Information
Symbol
Scer\GAL4H24
Species
S. cerevisiae
Name
FlyBase ID
FBal0117654
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
H24-GAL4, H24
Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Mutations Mapped to the Genome
     
    Type
    Location
    Additional Notes
    References
    Associated Sequence Data
    DNA sequence
    Protein sequence
     
     
    Progenitor genotype
    Cytology
    Nature of the lesion
    Statement
    Reference
    Insertion components
    P{GawB}H24
    Product class / Tool use(s)
    Expression Data
    Reporter Expression
    distribution deduced from reporter (Gal4 UAS)
    Stage
    Tissue/Position (including subcellular localization)
    Reference
    Additional Information
    Statement
    Reference

    Drives expression in gamma lobe Kenyon cells in the mushroom body.

    Scer\GAL4H24 labels the mushroom body gamma neurons. Co-expression with presynaptic and postsynaptic markers labels distinct domains of Kenyon cell terminals in the calyx of the mushroom body.

    Expression of Scer\GAL4H24 is seen in cell bodies found in the local interneuron cluster located lateral and dorsolateral to the antennal lobe. Most labelled cells are ipsilaterally projecting interneurons.

    Scer\GAL4H24 drives expression in mostly GABAergic antennal lobe local interneurons, and in a subset of olfactory projection neurons and Kenyon cells.

    In the mushroom body, Scer\GAL4H24 drives expression in the whole of the gamma lobe, although with different intensities: the main body of the lobe stains stronger than the dorsomedial tip.

    Expression of Scer\GAL4H24 is seen in approximately 40 cells of the ellipsoid body neurons that arborize in the periphery of the ring neurons.

     
    Reflects expression of
    Reporter construct used in assay
    Human Disease Associations
    Disease Ontology (DO) Annotations
    Models Based on Experimental Evidence ( 0 )
    Disease
    Evidence
    References
    Modifiers Based on Experimental Evidence ( 0 )
    Disease
    Interaction
    References
    Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
     
    Phenotypic Data
    Phenotypic Class
    Phenotype Manifest In
    Detailed Description
    Statement
    Reference

    Inhibition (using shi1.UAS at 32[o]C) of Scer\GAL4H24 cells in adults does not affect startle-induced climbing behavior, compared to controls.

    Thermogenetic activation (using TrpA1UAS.(B).cKa at 32[o]C) of Scer\GAL4H24 cells in adults does not affect startle-induced climbing behavior, compared to controls.

    Inhibition (using shi1.UAS at 32[o]C) of Scer\GAL4H24 cells in adults significantly reduces 5 min (single-trial conditioned), but not 30 min (multiple-trial conditioned) aversive taste memory, compared to controls; inhibition of a subset of Scer\GAL4H24 cells (restricted using Scer\GAL80Mef2.mb247) does not affect 5 min (single-trial conditioned) or 30 min (multiple-trial conditioned) aversive taste memory, compared to controls.

    External Data
    Interactions
    Show genetic interaction network for Enhancers & Suppressors
    Phenotypic Class
    Phenotype Manifest In
    Additional Comments
    Genetic Interactions
    Statement
    Reference
    Xenogenetic Interactions
    Statement
    Reference
    Complementation and Rescue Data
    Images (0)
    Mutant
    Wild-type
    Stocks (1)
    Notes on Origin
    Discoverer
    External Crossreferences and Linkouts ( 0 )
    Synonyms and Secondary IDs (1)
    Reported As
    Symbol Synonym
    Scer\GAL4H24
    Name Synonyms
    Secondary FlyBase IDs
      References (28)