Allele Dmel\Inx3^Scer\UAS.cSa

General Information
Symbol	Dmel\Inx3^Scer\UAS.cSa	Species	D. melanogaster
Name	Saccharomyces cerevisiae UAS construct a of Stebbings	FlyBase ID	FBal0118190
Feature type	allele	Associated gene	Dmel\Inx3

Allele class
Mutagen	in vitro construct - regulatory fusion
Recent Updates
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FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Nature of the Allele
Allele class
Mutagen	in vitro construct - regulatory fusion (Stebbings et al., 2000)
Mutations Mapped to the Genome

Type Location Additional Notes References
Associated Sequence Data
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name

UniProtKB/Swiss-Prot
UniProtKB/TrEMBL

Progenitor genotype
Nature of the lesion	Statement Reference Construct: Scer\UAS regulatory sequences drive expression of inx3 EST LD17559. (Stebbings et al., 2000)
Carried in construct	P{UAS-inx3.S} (Stebbings et al., 2000)
Cytology
Phenotypic Data
Phenotypic Class

Phenotype Manifest In

Detailed Description
	Statement Reference Expression of inx3^Scer\UAS.cSa under the control of Scer\GAL4^how-24B results in similar hatch and eclosion rates as controls. (Stebbings et al., 2000)
External Data
Linkouts
Interactions
	Show the genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Enhancer of
Statement Reference Scer\GAL4^how-24B, Inx3^Scer\UAS.cSa, Scer\GAL4^how-24B is an enhancer of lethal phenotype of Scer\GAL4^how-24B/Scer\GAL4^how-24B, Inx2^Scer\UAS.cSa (Stebbings et al., 2000)
Other
Statement Reference Scer\GAL4^arm.PS, Inx2^Scer\UAS.cSa, Inx3^Scer\UAS.cSa has lethal phenotype (Stebbings et al., 2000, Stebbings et al., 2000)
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement Reference Co-expression of inx2^Scer\UAS.cSa and inx3^Scer\UAS.cSa under the control of Scer\GAL4^how-24B results in significantly lower viability than when inx2^Scer\UAS.cSa alone is expressed under the control of Scer\GAL4^how-24B; only 27% of embryos hatch and only 5.5% reach adulthood. Co-expression of inx2^Scer\UAS.cSa and inx3^Scer\UAS.cSa under the control of Scer\GAL4^arm.PS results in reduced survival rates compared to controls. (Stebbings et al., 2000)
Xenogenetic Interactions
Statement Reference
Complementation & Rescue Data
Comments
Stocks ( 0 )

Notes on Origin
Discoverer

External Crossreferences & Linkouts
Other Crossreferences

Linkouts

Synonyms & Secondary IDs ( 3 )
Reported As
Symbol Synonym	inx3^Scer\UAS.cSa Inx3^Scer\UAS.cSa
Name Synonym	Saccharomyces cerevisiae UAS construct a of Stebbings (Stebbings et al., 2000)
Secondary FlyBase IDs

References ( 1 )
Research paper	Stebbings et al., 2000, Mol. Biol. Cell 11(7): 2459--2470 Two Drosophila innexins are expressed in overlapping domains and cooperate to form gap-junction channels. [FBrf0128653]

Allele Dmel\Inx3Scer\UAS.cSa

Allele Dmel\Inx3^Scer\UAS.cSa