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General Information
Symbol
Dmel\emb2
Species
D. melanogaster
Name
FlyBase ID
FBal0118251
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
point mutation
Nucleotide change:

T8405522G

Reported nucleotide change:

T?G

Amino acid change:

M412R | emb-PA; M412R | emb-PB

Reported amino acid change:

M413R

Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference

Amino acid replacement: M413R.

Nucleotide substitution: T?G.

Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Homozygous emb2 mutant larvae die at the 2nd instar stage (approximately 70 hours after egg laying).

The most advanced stage seen in emb2/Df(2L)N22-14 animals is the 2nd larval instar.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Suppressed by
Statement
Reference

emb2 has lethal phenotype, suppressible by mbo1

Phenotype Manifest In
Other
Additional Comments
Genetic Interactions
Statement
Reference

Removal of one copy of mbo1 from emb2 homozygous mutants prolongs the life span of 20% of the individuals to the 3rd instar larval stage (approximately 120 hours after egg laying). This prolonged survival is accompanied by eversion of the anterior spiracles, a morphological characteristic of progression through larval development.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
Name Synonyms
Secondary FlyBase IDs
    References (2)